How do hormonal contraceptives work on endometriosis? Hormonal drugs for endometriosis. Side effects during treatment

Last update articles 07.12.2019

Endometriosis is a hormone-dependent pathology characterized by abnormal growth of the endometrium of the uterus inside and outside the organ. Gynecologists believe that the main reason for the development of the disease is a violation of the stability of the level of female sex hormones. Hormonal therapy is mainly used to treat the disease. The patient is recommended long time take various birth control pills for endometriosis.

Hormonal therapy is considered the most optimal in the treatment of endometriosis, since it not only helps eliminate the unpleasant symptoms of the pathology, but also, unlike surgical treatment methods, preserves the functions of childbearing. Hormonal contraceptives contain synthetic analogues of female sex hormones - estrogen and progesterone. Therefore, COCs not only reliably protect against unwanted pregnancy, but also have a therapeutic effect in the treatment of gynecological diseases.

COCs for endometriosis have the following positive effects:

reduce or completely remove premenstrual pain;
normalize the menstrual cycle, reduce the amount of blood loss;
reliably protect against unplanned conception;
suppress foci of endometriosis, reduce blood flow in them, and prevent the appearance of new growths;
eliminate pain syndrome;
prevent complications (endometrial hyperplasia, inflammation);
promote stable remission.

Due to the hormonal effect of the tablets, the patient’s own production of female sex hormones is reduced, slowing down the progression of the disease. As a result, the menstrual cycle is restored, heavy bleeding stops, hemoglobin levels normalize, and painful sensations and discomfort improves general state health.

It is important to remember that hormonal therapy only helps with endometriosis. initial stages development of pathology.

In addition, it is impossible to completely cure the disease; even after long-term treatment, relapses occur quite often. In the final stages, patients are advised surgery, during the operation, endometriotic tissue is removed. In particularly severe cases, the uterus must be completely removed.

What contraceptives are used to treat endometriosis?

The modern pharmaceutical market offers many drugs for hormonal therapy of endometriosis. Most of them are complete analogues of each other, differing only in the composition of the excipients, which ensure the most rapid absorption of hormones into the body.

Before prescribing treatment, the doctor must determine which hormones are missing or, on the contrary, too much in the patient’s body. The effectiveness of treatment depends on these indicators. Therefore, a thorough laboratory and instrumental diagnosis is first carried out, and only after that treatment tactics are selected and oral hormonal contraceptives for endometriosis are prescribed.

Gynecologists identify several of the most popular means. These drugs are time-tested and have earned recognition among doctors and patients due to their effectiveness and speed of action, as well as the safety of their use.

These hormonal agents combine several active substances that help normalize female hormonal levels and eliminate the symptoms of endometriosis.

List of the best hormonal drugs

Which birth control pills are best to take for endometriosis should be determined by your attending gynecologist. Self-treatment unacceptable, as it can seriously aggravate the disease, which is fraught with serious complications.

Utrozhestan, Duphaston

Preparations containing progesterone are prescribed when there is a deficiency of this hormone in the body. These medications reduce the production of estrogen, which suppresses the pathological growth of the endometrium. Pill therapy is especially effective in the initial stages of endometriosis.

The duration of treatment and dosage should be determined by the gynecologist. All hormonal medications are taken according to a strict schedule. When taking these particular hormonal drugs, you must follow all the doctor’s recommendations. This is explained by the narrow focus of action and the inability of the drug to influence severe forms of endometriosis. When treating women over 40 years of age, constant medical supervision is necessary.

When treating endometriosis with hormonal drugs of this group, the following may appear: adverse reactions, such as acyclic bleeding, amenorrhea, headache, bloating.

Among the main contraindications: tendency to thrombosis or thromboembolism, uterine bleeding unknown nature, incomplete abortion, malignant neoplasms, liver dysfunction, individual intolerance.

Janine and Yarina

New generation estrogen-gestagen drugs are effective on early stages endometriosis. Thanks to its complex composition, they compensate for the production of natural hormones estrogen and gestagens. These oral contraceptives are used for the purpose of hormonal correction, contribute to a significant inhibition of the progression of pathology, and also slow down ovulation, preventing endometriotic lesions from activating.

The use of these contraceptives helps to normalize menstrual cycle, reduces the pain of menstruation. Blood loss becomes less abundant, and the risk of developing anemia decreases. The drugs have antiandrogenic activity, due to which the oiliness of the skin and hair decreases, acne. In general, the drugs have a positive effect on women’s health and reduce the risk of developing hormone-dependent tumors, therefore they are often prescribed to women after 40 years of age.

A positive effect in the treatment of endometriosis is achieved after 6 months of regular use. mostly have positive statistics. Oral contraceptives are taken 1 tablet daily, for a course of 21 days, then take a seven-day break. Blisters are convenient to use, since the manufacturer puts the names of the days of the week according to the days of administration directly on the primary packaging above each tablet. According to indications, the doctor may choose a different treatment regimen.

Contraindications: thrombosis, diabetes, pancreatitis, kidney and liver pathologies. Please read the instructions before use.

Novinet

Novinet is a combined hormonal drug, mainly used as an oral contraceptive, but is considered an effective drug in the treatment of endometriosis. The main advantage of Novinet is that the drug can be used a few days after the birth of the child and during breastfeeding.

COC reduces the severity of menstrual periods pain syndrome, reduces the amount of bleeding, restores hormonal balance. It is worth noting that Novinet does not have a cumulative therapeutic effect for endometriosis, so improvements are observed only when taking the drug; relapses are possible after discontinuation. In the initial stages of the pathology, it can be recommended for women after 40 years of age, but with rapid progression of the disease, it is better to choose another medicine.

Zoely

Zoely is a microdose combination drug used for oral contraception. The active substances here are nomegestrol acetate and estradiol. These components are as identical as possible to natural female hormones. Therefore, side effects do not occur so often when taking Zoely. The positive effects of the drug include reliable contraception, reduction of pain during menstruation, restoration of the cycle, prevention female oncology, noticeable improvement in skin condition. Well suited for women over forty to reduce relapses of endometriosis.

Zoely for endometriosis is prescribed only in the initial stages; with advanced pathology, the drug is ineffective.

One blister contains 28 tablets, which are taken 1 tablet at the same time daily. After finishing the first pack, take the tablets from the second pack immediately without a break. After discontinuation, Zoely is quickly eliminated from the body and does not affect hormonal levels.

Regulon

Regulon is a monophasic hormonal contraceptive, that is, each tablet contains the same dose of hormones. The drug is effective in treating premenstrual syndrome, vaginal bleeding, endometriosis. The contraceptive gives positive dynamics, reducing the growth activity of pathological foci of the endometrium.

Regulon is a low-dose hormonal drug, it is well suited for women over 40 years of age. For endometriosis, Regulon helps stabilize and alleviate the patient's condition. The drug delays the process of proliferation of the uterine mucosa and normalizes the menstrual cycle. Therapy for endometriosis with this medicine lasts continuously for 6 to 9 months. Based on the results of the examination, the gynecologist determines the need to replace or discontinue the drug.

Jess and Silhouette

Jess and Silhouette are low-dose contraceptives, mainly prescribed to young nulliparous women. COCs contain minimum doses female hormones, are used only for complex treatment endometriosis. The drugs have a depressing effect on the ovulation process, making cervical mucus more viscous, protecting against unwanted pregnancy.

Endometriosis can be studied in detail in a separate article.

The positive effect in endometriosis is expressed in the stabilization of hormonal levels, reduction or complete removal pain syndrome, reducing blood loss during menstruation. Also, when taking these contraceptives, acne goes away, hair condition improves and skin, swelling in the periphery is eliminated. Due to the antimineralocorticoid effect, body weight does not increase while taking the tablets.

Intrauterine devices for the treatment of endometriosis

Mirena spiral has a pronounced gestagenic effect with the help of the levonorgestrel contained in it. The active substance acts directly on the cells of the uterus, reducing the sensitivity of endometrioid tissues to female sex hormones and stopping their pathological growth.

The Mirena spiral is used in fairly severe cases of endometriosis, when the affected endometriotic tissue has been surgically removed.

Spirals are usually prescribed to maintain the stability of the uterus and prevent subsequent uncontrolled proliferation of endometrial cells.

Mirena is distinguished not only by its unique shape and release process active substance, but also the duration of action. It does not need to be replaced for 5 years; the hormones it contains are released every day in a therapeutic dosage of 20 mg. In addition, unlike older intrauterine forms, Mirena does not grow into the uterine cavity due to its increased flexibility.

Ring NuvaRing has similar action, however, it has a very short period of use - 1 month. Then the doctor removes it, if necessary, waiting for the time for menstruation, then introduces a new one. The ring is prescribed in less severe cases of pathology. Used to treat cervical erosion. Well suited for women over 40 years old.

Important! All hormonal drugs can be taken only after consultation with a gynecologist. Self-medication leads to dire consequences, so don’t risk your health!

The effectiveness of any therapy largely depends not only on the stage of the pathology, but also on the patient’s attentiveness to her health. Timely consultation with a doctor will help reduce the risk of worsening the disease and speed up the process of getting rid of the disease.

Endometriosis is a pathological growth of endometrial tissue in or outside the uterus. One of the therapeutic methods for this pathology is the use of birth control pills not only to prevent pregnancy, but also to treat endometriosis.

To treat endometriosis, gynecologists prescribe injections, intrauterine devices, or birth control pills that can be taken at home.

The form of capsules and film-coated tablets is convenient for oral administration and has fewer undesirable effects and side effects.

Varieties

Traditionally, all contraceptives for the treatment of endometriosis are divided into groups:

mechanical (condoms, caps, spirals);
biological (pills with female hormones);
chemical (suppositories, tampons, vaginal creams).

The best drugs for the treatment of endometriosis are considered to be COCs - new generation combined oral contraceptives: Ciproperone acetate, Drospirenone, Gestodene, Desogestrel.

Tablets for age group 35

Thirty five years - new stage in a woman's life:

the functions of the reproductive system decline;
the synthesis of progesterone and estrogen decreases;
many chronic diseases are getting worse;
the risk of developing cardiovascular pathologies increases.

But sex life is still ongoing, so to avoid harm female body After 35 years, it is recommended to take reliable contraceptives.

How to choose the right one

Contraceptive drugs must meet the following requirements:

be safe, with a minimum of side effects;
well tolerated by the body.

Contraceptive selection scheme

The scheme for selecting contraceptives for the treatment of endometriosis is compiled individually for each woman. This takes into account:

age, characteristics of premenstrual or postmenstrual syndrome;
features of the menstrual cycle;
type of constitution of a woman, features of secondary sexual characteristics;
the presence of concomitant, general and gynecological diseases.

Antiprogestins

Antiprogestins are drugs that suppress progestin synthesis (Danazol, Bonzol, Mifegin, Mifepristone).

They are effective in the treatment of endometriosis, but have side effects - they cause weight gain and depression of the psycho-emotional state.

Danazol, Mifepristone belong to the group of potent medicines, therefore they are used only in hospital settings.

Gonadotropin-releasing antagonists

Gonadotropin-releasing hormone (GnRH) is produced by cells of the hypothalamus and affects the production of follicle-stimulating and luteinizing hormones.

A change in the time of physiological entry of GnRH into the blood leads to disruption of ovulation and the menstrual cycle. Created analogues of this hormone - Diferelin, Buserelin, Zoladex - are prescribed for the treatment of many female pathologies, for example, endometriosis.

Gestagens

Gestagens - a group of the most important steroid hormones, the action of which is aimed at achieving conception and maintaining a full course of pregnancy.

Hormones are produced mainly by the ovaries, the corpus luteum, partly the placenta and the adrenal cortex. Based on them, such dosage forms as Duphaston, Ovestin, Progesterone, Zhanin, Yarina are produced.

Oral contraceptives

COCs are combined oral contraceptives with estrogen and progestin components, considered the most harmless for the woman’s body:

reduce FSH (follicle-stimulating hormone) and LH (luteinizing hormone);
lead to the absence of ovulation and menstruation;
due to changes in natural hormonal levels, the progression of endometriosis is stopped.

The drugs are easy to use and are available in different price categories, so they are available to women of any income.

Like any dosage forms, they have some contraindications: they are not prescribed for organ diseases endocrine system, liver diseases, kidney diseases, heart pathologies, increased thrombus formation, pregnancy or lactation.

Janine and Yarina

Zhanin, Yarina - hormonal contraceptives from a German company, which have proven themselves in the treatment of endometriosis. The drugs are almost identical in composition, but still have some differences:

Yarina is a newer development, has a faster absorption period (about 1.5 hours);
has fewer contraindications, has a prolonged effect;
does not cause weight gain, reduces swelling;
Janine is not prescribed for impaired metabolism (metabolism).

Regulon

To treat endometriosis, if the patient has no contraindications, Regulon tablets are used. These birth control pills help especially well in the early stages of pathology:

inhibit ovulation;
reduce pain;
reduce blood loss and stop the growth of the uterine mucosa.

Qlaira drug

The drug is characterized by high efficiency:

prevents the transition of endometriosis to malignant formations;
contains an estrogen analogue;
does not provide negative influence to the liver.

The treatment is long-term. The first results can be observed after six months.

Mirena spiral and NuvaRing ring

For the treatment of endometriosis, in addition to tablets and injections, contraceptives in the form of spirals and special contraceptive rings are used:

the Mirena hormonal intrauterine device is valid for 5 years, contains the slowly released progesterone hormone, inhibits the spread and growth of endometrial lesions;
the NuvaRing ring contains a small amount of hormones, therefore it is considered practically safe, is inserted vaginally, protects the body from pathological growth endometrium.

Jess

Prescribed for the treatment of endometriosis in women before menopause. Not for pregnant and lactating women. Taking Jessa tablets can lead to the development of migraines, nausea, and pain in the genitals.

Contraceptive injections

Hormonal contraceptive injections are used not only for contraception, but also for the treatment of endometriosis:

inhibit ovulation processes;
block the growth and metastasis of the endometrium;
reduce the likelihood of relapse of the disease.

Depo Provera injections are most effective for endometriosis. The medicine is administered intramuscularly, maintaining its therapeutic effect for up to 12 days. It has contraindications: liver disease, epilepsy, cardiovascular pathologies.

Utrozhestan and Duphaston

Hormonal herbal preparation, available in capsules for oral or vaginal administration. Prescribed for the prevention and treatment of endometriosis, helps maintain pregnancy.

The treatment regimen (at least two weeks) is determined by the gynecologist. Utrozhestan and Duphaston are contraindicated in case of circulatory problems, liver or kidney pathology, or neoplasms.

Goserelin

Goreselin is injected with a special syringe into abdominal cavity every 28-30 days. The course of treatment is determined by a specialist. When treated with Goreselin, pain, size, and the number of affected areas decrease.

Contraindications: pregnancy, breast-feeding. One of the important side effects is a high likelihood of permanent menopause.

Danazol

Causes atrophy of endometrial tissue, effective for benign breast tumors. Not recommended for pediatric therapy or elderly patients.

Danazol tablets are prescribed with extreme caution when diabetes mellitus, since the drug reduces the effectiveness of insulin.

Dienogest

Reduces estrogen production, promotes atrophy of pathological endometriotic tissue. Treatment with the drug is long-term, at least six months. It has a number of contraindications and side effects, like other hormonal drugs.

When prescribing Dienogest, one must take into account its incompatibility or changes in pharmacotherapeutic activity when combined with certain dosage forms, for example, Rifampicin, Indinavir.

Byzanne

A new generation hormonal drug is an analogue of the female hormone:

inhibits estrogen production;
reduces inflammation, reduces pain;
reduces growth and pathological spread blood vessels, providing nutrition to the enlarged endometrium;
normalizes the condition of the endometrium.

Taking Visanne tablets is contraindicated in diabetes, atherosclerosis, cardiovascular pathologies, pregnancy or lactation. Advantages - does not inhibit the likelihood of conception and development of a full pregnancy.

Depo Provera

A hormonal drug that exhibits high antitumor activity. It is often prescribed as an additional treatment in the treatment of endometrial cancer.

Contraindicated in bronchial asthma, thrombosis, thromboembolism, diabetes mellitus, diseases of cardio-vascular system, pregnancy, lactation.

Side effects: causes disturbances emotional background, insomnia, dizziness, weight gain, long term reduces the likelihood of pregnancy.

Buserelin

Normalizes hormonal balance, affects the endometrium, causing its degradation and thinning. The drug is available in two forms:

nasal spray, the use of which is recommended at home;
injection solution administered only in a medical facility.

The spray should be used every day during the course of treatment, injections are administered once every four weeks, which makes the use of this form more convenient for patients.

Contraindications: pregnancy, lactation, severe forms of diabetes, arterial hypertension.

Diferelin

Synthetic drug for subcutaneous or intramuscular injection. The duration of treatment is from 3 to 6 months.

The drug causes artificial menopause, which is difficult for some women to tolerate due to hot flashes, weakness, and fatigue.

Treatment with Diferelin inhibits further growth of the endometrium, avoiding surgical treatment. After stopping the drug, the menstrual cycle is restored and the chances of pregnancy increase.

Zoladex

Drug for subcutaneous administration. Reduces the concentration of the hormone estradiol in the blood serum, prevents the development of uterine fibroids, leads to thinning of the inner muscular layer of the uterus, therefore it is effective for endometriosis.

Not prescribed during pregnancy, lactation, hypersensitivity to the components of the drug.

When taking the medicine, there may be a cessation of menstruation and a decrease in mineralization bone tissue, restored after stopping Zoladex.

Drugs prescribed for the treatment of endometrium contain hormones, so self-medication is unacceptable.

Only a specialist, a gynecologist, will help you choose the forms that will be the safest for a particular patient.

Many women have had to deal with a disease such as endometriosis. It should not be confused with endometritis, since these are two various diseases, each of which is dangerous to health in its own way. In short, this is the growth of the endometrium.

How to treat uterine endometriosis medically and surgically? Is it treated at all and with what medications, how to prevent the disease and its complications? All this will be discussed further.

Treatment regimen for uterine disease in women

Treatment for endometriosis must be systemic due to the fact that this disease can occur for many reasons. Treatment of endometriosis involves treating the entire body, not individual systems or organs.

To determine a treatment strategy, the physician should consider the following:

duration of illness;
state of immunity;
the nature of the violations that occurred;
symptoms;
spread and localization of the disease process;
woman's age;
the prospect of pregnancy planning.

There are three ways to treat endometriosis, which are chosen depending on the general indications. This is combined, surgical and conservative.

Is it possible to cure uterine endometriosis permanently without surgery? This rarely happens. Mostly, To conservative method Doctors resort to treating endometriosis when:

infertility;
woman's reproductive age;
asymptomatic pathology.

Doctors resort to the surgical method when:

somatic pathology;
the occurrence of other diseases of the genital organs;
endometriosis of postoperative scar;
navel endometriosis;
adhesive process affecting the ampullary sections of the fallopian tubes;
purulent processes;
ineffectiveness of drug therapy;
the presence of large ones, with a diameter of 5 centimeters;
adenomyosis.

Surgical treatment of endometriosis can be organ-preserving or radical. The choice of method will depend on the patient’s age and the degree of damage to her internal organs.

Radical surgical treatment is prescribed for the following pathologies:

common retrocervical endometriosis;
severe adenomyosis;
diffuse or nodular form of adenomyosis, accompanied by fibroids;
ovarian endometriosis, which can lead to malignancy ();
development of the disease after the ineffective use of conservative or conservative surgical methods.

Organ-conserving surgical treatment should be carried out in compliance with the principles:

maintaining thorough and complete hemostasis;
desire for atraumaticity and anatomy;
restoration of the physiological location of internal organs during treatment and tissue preservation;
removal of adhesions and endometriotic foci in healthy tissues of the body.

With conservative surgical treatment, the operation should be performed with minimal trauma. It consists of affecting non-pigmented, microscopic or hard-to-reach lesions. The doctor must ensure that the period required for pregnancy to occur is adequate.

Video about the types of endometriosis and how to get rid of it:

Birth control pills (hormonal OCs)

For endometriosis, doctors prescribe treatment with oral contraceptives - hormonal birth control pills. They are able to block the growth of the uterine lining and inhibit ovulation, which helps in the fight against endometriosis. The disadvantage of this treatment is its duration.

The period of hormonal therapy for endometriosis lasts from 6 to 16 months according to the pill regimen (daily intake or between periods).

The table provides instructions for the use of hormonal drugs for endometriosis - Silhouette, Norkolut, Utrozhestan, Yarina, Regulon, Qlaira, Nuvaring, Jess, Novinet and Logest.

Drug name	Short description	Application	average price
Silhouette	Combined hormonal pills Silhouette for endometriosis is taken orally. The drug has an antiandrogenic and anti-inflammatory effect. The active substance is ethinyl estradiol.	How to take Silhouette for endometriosis? Every day, 1 tablet per day with water. It is better to do this at the same time to enhance the effect of taking it. The duration of the course is 3 weeks.	620 rubles
Norkolut	Peculiarity of this medicine lies in its rapid absorption from the gastrointestinal tract. The active substance is norethisterone. The product begins to act within 1.5-2 hours after administration.	Norkolut should be taken between days 5 and 15 of the menstrual cycle. The daily dosage is 5 milligrams. The duration of the treatment course is 6 months.	117 rubles
Utrozhestan	A popular progestin drug used to treat endometriosis. The active substance is progesterone (this is a hormone corpus luteum). It increases the utilization of glucose in the blood and also increases fat reserves.	The drug is taken orally. Its daily dose is from 200 to 400 milligrams, which should be divided into two servings. Take the first in the morning, and the second in the evening.	402 rubles
Yarina	Antiandrogenic drug, helps reduce acne. Reduces the activity of the sebaceous glands.	You need to take Yarina 1 tablet every day. It is better to do this at the same time, with water. The duration of treatment is 3 weeks, after which you need to take a week break.	1000 rubles
Regulon	Monophasic contraceptive drug of a hormonal nature. Active ingredients: desogestrel and ethinyl estradiol. The drug stimulates the pituitary secretion of human sex hormones.	Take 1 tablet daily. In order for the effect of therapy to be greater, you need to regularly take the drug at the same time. You need to start taking it from the first day of the menstrual cycle. The duration of the therapeutic course is 21 days.	420 rubles
Claira	A combined contraceptive drug that helps change the properties of cervical fluid and suppress ovulation.	Qlaira is taken daily according to the instructions attached to it. This should be done at the same time, with a small amount of water. You cannot interrupt the course. The duration of the therapeutic course is 28 days.	1100 rubles
Nuvaring	A hormonal contraceptive drug of combined action, which includes active ingredients such as ethinyl estradiol and etonogestrel. Available in the form of a special ring for the vagina.	Nuvaring is inserted into the vagina for three weeks. During this time, the woman should regularly check for its presence.	1200 rubles
Jess	Monophasic contraceptive used to combat endometriosis. Jess is administered orally. Has antiandrogenic properties.	You should take the drug daily, one tablet per day, with water. The duration of the treatment course is 28 days. It is strictly not recommended to interrupt the course. To enhance the effect, you need to take the tablets at the same time.	1065 rubles
Novinet	A hormonal contraceptive drug of combined action, intended for systemic use. Helps suppress ovulation.	Take the medicine for uterine endometriosis, one tablet a day for 3 weeks. After the course you should take a 7-day break, then repeat the course again.	470 rubles
Logest	Hormonal combination drug for oral use. Thanks to active components, contained in this contraceptive, suppresses ovulation and normalizes the properties of cervical mucus.	Logest is available in tablet form, so it should be taken with a small amount of water. Take one tablet daily for three weeks. It is advisable to do this at the same time.	650 rubles

Endometriosis can spread to other organs and even cause tumors in them. One of the closest organs is the bladder. about cancer diagnosis Bladder among women.

Non-hormonal drugs

Is it possible to cure endometriosis without hormones and how to treat the disease in this way? Some try to avoid strong hormonal medications or surgery. In such cases, non-hormonal drugs will help overcome the disease.

There are medications for the treatment of endometriosis without hormones and surgery - Endoferin, Wobenzym, Ovariamin, Cyclodinone and Indomethacin. Their application diagrams are in the table below.

Drug name	Short description	Application	average price
Endoferin	Effective non-hormonal agent for the treatment of endometriosis, promoting atrophy of ectopic endometrial tissue. It has anti-inflammatory and analgesic properties, which helps to reduce endometriotic lesions.	The treatment course is divided into 3 periods and lasts 90 days. First, Endoferin is administered at a dose of 0.3 milligrams daily for 10 days. Then the dosage increases, but it is prescribed by the doctor, based on the patient’s condition.	1000 rubles
Wobenzym	This is a unique combination of natural enzymes of animal and natural origin. Active components are quickly absorbed small intestine and spread in the blood. Available in tablet form.	Take 30 minutes before meals and wash down with plenty of water. Depending on the severity of the disease, the dosage may vary. At first, you need to take no more than three tablets at a time, three times a day. After 3 days, the dosage is increased.	1200 rubles
Ovariamine	The drug is a dietary supplement with complex action. Leads to a reduction in the gonadotropic function of the adenohypophysis and a decrease in the amount of follicle-stimulating hormones in the body.	Ovariamine is taken daily before meals. The recommended dosage is 1-9 tablets per day, divided into 2-3 doses. The treatment course is 14 days.	750 rubles
Cyclodinone	Vegetable medicinal product, used for pathologies of the female reproductive organs. Thanks to the active components, Cyclodinone normalizes the level of sex hormones.	Available in the form of tablets or drops. In the first case, you need to take one tablet daily with water. The solution is taken 40 drops once a day. The duration of the treatment course is 3 months.	490 rubles
Indomethacin	A non-steroidal drug with anti-inflammatory properties. The active substance is prostaglandins.	Apply 25 milligrams 2-3 times a day. Over time, the dose may be increased depending on individual tolerance (100 milligrams 3 times a day).	100 rubles

Therapeutic spiral Mirena

To combat endometriosis, the Mirena spiral is used - an intrauterine therapeutic system. It suppresses the growth of the endometrium (uterine mucosa). After entering the uterus, Mirena releases levonorgestrel(analogue of the female hormone - progesterone).

Mirena acts locally, which is why Get well soon you need less hormones than when taking pills.

While in the vagina, Mirena regulates the menstrual cycle, reduces the duration and volume of menstrual bleeding. Pain sensations decrease.

With Mirena, mild forms of endometriosis can be cured quickly, since during treatment there is a reverse development of the foci of the disease.

After installing the Mirena coil for endometriosis Increased spotting and bleeding may occur, but after a few cycles the situation improves. Your periods will become less long and heavy due to the regularization of the menstrual cycle.

In rare cases, periods may stop, which is not bad for endometriosis. This is due to the fact that during menstruation the disease can spread.

What else is used to treat: names of suppositories in gynecology

In the treatment of endometriosis, suppositories are used only in cases where a good analgesic effect is needed without the use of analgesics.

Non-steroidal anti-inflammatory suppositories are used, the most effective of which are Diclofenac and Indomethacin. These remedies reduce pain.

Doctors may prescribe the following rectal anti-inflammatory suppositories:

Flamax - applied once a week. The active substance is ketoprofen;
Diclofenac - used daily, 1 suppository;
Voltaren is a very strong analgesic, used twice a day, morning and evening;
Movalis - used daily, 1 suppository before bedtime. The duration of the therapeutic course is 1 week;
Indomethacin - used daily before bed.

What antibiotics are prescribed

Antibiotics are used only when the disease is accompanied by the development of an infectious inflammatory processes. In such cases, doctors prescribe medications broad action. These include Doxycycline, Tienam, Macrolide and Penicillin.

Doctors can prescribe and medications included in the cephalosporin group. These are Cedex, Ceftriaxone, Ceftazidime and other drugs that are introduced into the body through droppers or injections.

If the disease has acquired running form, your doctor may prescribe antifungal antibiotics. This happens only in cases where insufficient attention was paid to complications. The group of such drugs includes Nystatin, Flucostat and Mikosist.

Invasive and minimally invasive surgery

TO surgical intervention resorted to increase fertility (fertility) and alleviate the symptoms of the disease. This helps to destroy or remove endometrial formation. Depending on the location of the tissue, the type of operation may vary.

Surgical methods for treating endometriosis:

hysterectomy;
laparotomy;
laparoscopy.

Hysterectomy used in extreme cases when none of the previously used methods helped.

This is a major operation to remove the uterus, so it should be performed if the woman no longer plans to have children. There is a small risk that even after the uterus is removed, the disease may reappear if the ovaries have not been removed.

Laparotomy is considered a more invasive operation that is performed when severe forms pathology. The doctor makes a small incision in the bikini area to access the affected endometriotic tissue.

The peculiarity of laparotomy is that after the operation it takes a lot of time to recover.

Laparoscopy is a common procedure in the treatment of endometriosis. Small incisions are made in the lower abdomen to remove endometrial tissue.

A wide incision is not needed because the doctor uses a medical instrument - a laparoscope. A laparoscope is a small tube equipped with a camera and a light source that allows the doctor to see an image of the abdominal cavity.

Often the disease occurs due to non-compliance with prevention rules. To protect your body, you need to fulfill several conditions:

observe the rules of personal hygiene;
protect yourself from diseases that can be transmitted through sexual intercourse. To do this, you need to use contraception, avoid intimacy with partners in whom you are completely unsure;
treat chronic or infectious pathologies. This will stop the disease in its early stages. Otherwise, it will begin to progress and therapy will take much longer;

Contact your doctor immediately if suspicious symptoms appear. You cannot put off treatment or a visit to the doctor until later. The same applies to self-medication. Endometriosis is serious illness, requiring serious measures.
undergo gynecological examinations for prevention purposes. This will allow the disease to be detected at an early stage.

We invite you to watch a video about where uterine endometriosis can spread, how to treat it, and whether it needs to be treated at all:

Endometriosis is much more dangerous than a runny nose or cough, as it can cause infertility. In rare cases, incorrect or untimely treatment can provoke malignant tumors. Try to lead healthy image life and follow preventive measures. Be healthy!

Endometriosis is a pathology that is common among women. When the disease grows benign tumor outside the uterus. Endometrial growths provoke the appearance of adhesions and inflammatory processes on the tissue of the pelvic organs and other organs. Endometriosis often occurs in combination with other hormonally determined diseases. The exact causes of the occurrence are not yet known, but doctors have identified some prerequisites for the appearance, increased exposure to estrogen, decreased immunity, and inflammatory reactions.

Treatment methods

Before starting treatment, you need to consult a doctor who will carefully study the medical history and be able to choose the right method that will not harm the patient.

Surgical method

It is used only after unsuccessful results of drug treatment. During treatment, a gentle intervention or a much more serious one, in which the pelvic organs are removed, is possible. A gentle method includes laparoscopy, which is often used by modern doctors. It allows surgery to be performed through a small incision using laser therapy or electrocoagulation.

Medication method

The method involves prescribing a woman a course of hormone therapy for endometriosis. These medications normalize the level of estrogen in the body and stabilize the functioning of the ovaries; hormones also stop endometriotic foci of inflammation. Used in early stages or in combination with surgical method. The patient's intake of hormonal drugs leads to the restoration and stabilization of her hormonal balance, which helps eliminate the symptoms of the disease. The basis of hormonal treatment for endometriosis is the cessation of menstruation caused by drugs to achieve positive results

Hormone therapy

Pros of hormone therapy:

Reduced pain;
Possibility to do without surgical intervention;
Preservation of a woman's reproductive capacity;

Disadvantages of hormone therapy:

Long-term use of hormonal drugs for endometriosis leads to disruptions in the functioning of the body;
Possibility of dependence on the drug;
Possible relapse;
Long duration of treatment;

In rare cases, hormone therapy for endometriosis has contraindications, so doctors select some other medications for the patient.

Contraindications to hormone therapy:

Allergic reactions to the drug;
Disruptions in the endocrine system;
Liver diseases;
Ulcer or gastritis;
Failures in the hematopoietic system;
Thrombosis;
Kidney diseases;
Diabetes;

Side effects:

The onset of depression;
Disruptions in the menstrual cycle;
The appearance of stable migraines;
Weight gain;
Edema;
Nausea;
Uterine bleeding;
Weakening of the immune system;
Metabolic failures;

Treatment of endometriosis - video

Drugs for treatment

Hormones for endometriosis can be divided into several groups, which differ in purpose and effect, because patients come with different symptoms and are prescribed different drugs.

Agonists

Drugs that help stop menstruation and reduce estrogen production. When using them, signs of menopause may appear.

Preparations:

Diferelin (requires intramuscular administration from the beginning of the cycle for 1-5 days, repeat course carried out in a month);
Decapeptyl Depot (injected into a vein, also in the first days of the cycle, repeated after 28-30 days);
Zoladex (injected into the abdominal cavity, effective for a month);
Buserelin (injected into the muscle within a month from the first days of the cycle);
Lucrin-Depot (injection is carried out on the third day of menstruation, the procedure is repeated a month later);

Antigestagens

Drugs of this group lead to inhibition of the development of endometriotic cells, including those that begin their development outside the uterine cavity. When using the products, body hair, weight gain and acne may appear.

Preparations:

Danazol (capsules, dosage and time of administration are prescribed by a doctor);
Mifepristone, Gestrinone (cause anovulation, take no more than 200 mg per day);

Gestagens

For homeopathy for endometriosis, the doctor may prescribe progesterone analogues. Which act to suppress the proliferation of endometriosis cells, since with their greater predominance they are able to better suppress the estrogen hormone than other drugs.

Preparations:

Duphaston (can be replaced with Norkolut) (tablets that are taken from the 5th to the 25th day of the cycle and are also taken again in the new menstrual period, the treatment is gentle, since the effect occurs only on the endometrium);
Visanne or Femoston (femoston for endometriosis is taken every day in the amount of 1 tablet, the effect is on the growth of the endometrium and on the cessation of menstruation);
Orgametril (used to stop and appear foci of endometriosis, taken from 14 to 25 days of the cycle, 1 tablet every day, with heavy bleeding the doctor can increase the dose to 2 tablets; it is used only in the first stages of the disease);
Utrozhestan (Utrozhestan for endometriosis is taken in the form of tablets and vaginal suppositories, dosage is prescribed by a doctor);
Norkolut (norkolut helps block ovulation, it is not recommended to use during pregnancy or when planning pregnancy);

Oral contraceptives

Treatment with birth control pills for endometriosis can not only act as intended - regulating the reproductive system of the female reproductive system, but also act with the help of homeopathy on foci of inflammation, reducing their activity. In addition, contraceptives contain a gestogenic component, which can affect the course of the disease and have a positive result.

In order for the treatment to be successful, it is recommended to take OK in the treatment of endometriosis for six months; if a positive effect is achieved with the help of these tablets, the doctor may increase the course. Patients who have used them in their treatment for endometriosis leave only positive reviews.

Combined oral contraceptives (COCs) are one of the most popular types of hormonal contraception. COCs, in addition to their main function, reduce the amount of bleeding during menstruation and lower the level of pain, have a positive effect on emotional condition women.

Also, the advantages of COCs are that there are a small number of risk factors and possible side effects, which gives the patient a feeling of confidence when receiving homeopathy treatment. But the drugs have their own contraindications due to age; it is better not to take COCs for women over 35 years of age.

Preparations:

Janine;
Yarina;
Claira;
Dimia;
Jas;
Marvelon;
Diecyclen (diecyclen is most often prescribed for endometriosis);
Lactinet;
Jess;

Remember, in order to know what medications you need to take, you should definitely consult a doctor; women over forty years old need to take this issue especially seriously. Read the instructions for use carefully.

The most popular prescribed drugs for hormone therapy for endometriosis are:

Norkolut

Norkolut is taken from the 5th to the 25th day of the cycle, for six months, further continuation of the course is considered by the doctor. TO side effects include: migraines, nausea, fatigue, thrombosis. When using Norkolut, it is necessary to exclude the possibility of being in the body malignant tumors, it is not recommended to skip taking the drug.

Contraindications when using Norkolut:

Kidney and liver diseases;
Thrombosis;
Bleeding of the ureter;
Large body weight;
Herpes;
Allergic reactions;

The use of Norkolut during pregnancy and lactation is prohibited.

Terzhinan

Terzhinan has antifungal and antibacterial properties and is also used for inflammation. Side effects of Terzhinan include the appearance of allergic reactions.

The use of Terzhinan during pregnancy is possible only from the second trimester. The course of treatment with Terzhinan lasts from 10 to 20 days.

Jess

The drug Jess is taken for 28 days, one capsule per day. It is allowed to start taking the medication from day 3-5 of the menstrual cycle. After menopause (for women over 40 years old), Jess is not discharged.

Jess should not be used during pregnancy and breastfeeding.

Side effects of Jess include migraines, nausea, and pain in the genitals.

Orgametril

Orgametril suppresses ovulation and menstruation. Orgametril is contraindicated for liver disease, contraindicated during lactation and pregnancy, herpes. Side effects of Orgametril include: nausea, weight gain, irritability, depression, chest pain.

Orgametril is taken from the 14th to 25th day of the menstrual cycle.

Metipred

Metypred is contraindicated for women with stomach diseases, infectious and fungal infections, and diseases of the cardiovascular system.

The dose of Metipred is prescribed by the attending physician.

Side effects of Metipred include: vomiting, pancreatitis, arrhythmia, depression, paranoia.

Use during pregnancy when prescribed by a specialist.

Lactinet

Lactinet is contraindicated in case of liver diseases, thrombosis, lactose intolerance, diabetes mellitus. The use of Lactinet begins on the first day of the menstrual cycle. After termination of pregnancy, Lactinet is taken as prescribed by a doctor, depending on the trimester in which the termination occurred. Contraindicated during pregnancy.

Side effects of Lactinet: nausea, irritability, decreased libido, redness of the skin.

Take care of your health and do not neglect your appointments hormonal treatment endometriosis, this way you will achieve quick results.

Yes, and even more than that, in about a third of women who do not receive any treatment, it goes away on its own. It's work related immune system, which can recognize “unnecessary” endometrium and destroy it.

How is endometriosis treated?

Based on the above, endometriosis does not always need to be treated. In world gynecology there are three types of management of endometriosis:

Observation without treatment: this tactic is not suitable for everyone, but only if endometriosis was discovered by chance (for example, during an ultrasound or surgery for another reason), the foci of endometriosis are small and do not cause any inconvenience.

Treatment with medications: the most common treatment strategy. We will talk about it in more detail below.

Surgical treatment (operation): usually prescribed if drug treatment did not help or endometriosis led to serious disruptions in the functioning of internal organs. Surgery may also be required if endometriosis develops.

What medications are used to treat endometriosis?

The main medications for endometriosis that gynecologists prescribe are hormonal and affect the level of the body's own hormones. We will talk about 4 groups of drugs that are most often used in the treatment of endometriosis:

Birth control pills(oral contraceptives, OK): Zhanin, Yarina

Medicines containing progesterone and its analogues: Utrozhestan, Duphaston, Visanne

Gonadotropin analogues: Buserelin, Zoladex

Each of these groups of drugs affects the body differently.

Birth control pills (Zhanine, Yarina) and endometriosis

Your gynecologist can prescribe birth control pills (OC) for the treatment of endometriosis: Janine, Marvelon, Regulon and others. These medications contain varying doses of hormones, so be sure to consult your gynecologist before starting to take the medication.

Birth control pills help reduce painful sensations with endometriosis shortly before and during menstruation. For successful treatment Endometriosis requires taking OCs for at least 6 months. If the effect is noticeable (pain disappears), then your gynecologist may advise you to take OK for another 3-6 months. As a result of this treatment, areas of endometriosis may noticeably decrease in size.

Utrozhestan, Duphaston and endometriosis

Preparations containing progesterone ( female hormone) or its analogues, such as Utrozhestan, Duphaston, Depo-Provera, Visanne and some others give good effect in the treatment of endometriosis. These medications reduce the body's production of estrogen, which inhibits the growth of the endometrium (both in the uterus and in areas of endometriosis). It's better to prepare in advance long-term treatment, since the course of taking these drugs may take 6-9 months.

Danazol and endometriosis

Danazol is a synthetic hormone that, while taken, suppresses the production of female sex hormones, helping to reduce foci of endometriosis. For the therapeutic effect of Danazol to appear, it must be taken for at least 3-6 months.

This drug was previously widely used in the treatment of endometriosis, but in some countries doctors are beginning to abandon Danazol for several reasons. First of all, these are the side effects of Danazol, which include increased blood pressure, menstrual irregularities, weight gain, swelling and pain in the breasts, excess hair growth on the face and body, acne, hair loss and others. Secondly, new drugs have appeared in the arsenal of gynecologists that are as effective as Danazol, but without its side effects.

Buserelin, Goserelin (Zoladex) and endometriosis

Analogues of gonadotropin-releasing hormones, which include Buserelin, Goserelin (Zoladex), Sinarel and others, suppress ovarian function and reduce the level of female sex hormones in the blood. During treatment, you will not have periods, and you may also experience symptoms of menopause (hot flashes, mood swings), but this can be corrected by taking additional small doses of hormones.

The course of treatment for endometriosis with these drugs is no more than 6 months. After you stop taking the medication, the ovaries start working again, so you don’t have to worry that they will never “start” again.