The effect of citramon on the human body. Why can't you drink citramon? Does citramon help with headaches

Blood pressure is the pressure that is created in our blood vessels and, in particular, in the arteries. This pressure is necessary for the blood to be able to move through the circulatory system.

If the pressure is low, then the blood moves too slowly, respectively, it carries the substances and oxygen necessary for the body more slowly. As a result: the body, as a rule, is cold, hungry, and a headache develops from a lack of oxygen and vasospasm.

If the pressure is high, then the blood moves unnaturally fast, a big load is placed on the heart, the person becomes hot, there is noise in the ears, a pulsation in the temporal region. Excessive stress on the vessels provokes the appearance of a headache.

Pressure, as you know, has two indicators: systolic and diastolic. Systolic pressure is the pressure in the vessels that occurs at the moment of contraction of the heart, when it pushes the flow of blood into the circulatory system. Diastolic pressure is a measure of the pressure when the heart relaxes after systole. Thus, a pressure of 120/80 means that a person has arterial pressure at the moment of cardiac contraction is 120 mm Hg. Art., and at the time of cardiac relaxation - 80 mm Hg. Art.

We will talk further about how citramon affects pressure.

Due to caffeine, citramon enhances the processes of excitation in the brain, accelerates the conduction of positive conditioned reflexes and stimulates motor activity. The result is an increase in mental and physical capabilities, elimination of feelings of drowsiness and fatigue.

The degree of action of citramon on pressure is somewhat dependent on the characteristics of the individual nervous activity. For example, in a state of collapse and shock, blood pressure indicators under the action of citramon increase significantly. With stable normal values, significant changes may not be observed, since, together with an increase in vascular tone and acceleration of the heart, the drug expands the lumen of the vessels of the brain, heart, urinary system, skeletal muscles, etc. This to some extent compensates for the increase in pressure, but not completely: along with the expansion of the above vessels, those vessels that are located in the organs abdominal cavity, shrink.

The effect of citramone on pressure may also depend on the addiction of a particular organism to the effects of caffeine. If a person regularly consumes drinks with caffeine (coffee, strong tea, cola, energy drinks), then his body's tolerance increases. As a result, the pressure can remain stable even with the use of 200-400 mg of caffeine per day. But in people who do not have a tolerance to caffeine, signs of an overdose can develop as early as 100 mg of caffeine per day.

At what pressure do they drink citramon?

To understand at what pressure they drink citramon, let's look at the composition of the drug. The main ingredients of Citramon are: aspirin, paracetamol and caffeine.

Aspirin - eliminates pain, inflammation, lowers the temperature, reduces blood clotting. Everyone knows that aspirin is often used to prevent the formation of blood clots in the vessels. At the same time, aspirin does not affect the pressure in the vessels.

Let's move on: paracetamol is an analogue of phenacetin, but less toxic. It relieves tissue swelling caused by inflammation, eliminates pain, lowers temperature by influencing the thermoregulation centers in the hypothalamus. Again, on vascular pressure this substance has no effect.

And the last ingredient is caffeine. Here lies the answer to our question. We all know that coffee raises blood pressure. This happens just due to caffeine, which has the ability to increase vascular tone. Caffeine increases breathing and heart rate, eliminates fatigue, increases mental and physical abilities body, speeds up blood circulation.

Does citramon help with pressure?

We have already found out that citramon increases blood pressure. But to what extent? Does citramon help with low blood pressure?

One Citramon tablet contains 30 mg of caffeine. Let's compare how much of the same substance is contained in other well-known products that are advised to be consumed at reduced pressure:

  • a cup of ground coffee - 115 mg;
  • a cup of instant coffee - 65 mg;
  • a cup of black tea - 40 mg;
  • a cup of cocoa or hot chocolate - 4-15 mg;
  • a small jar of cola - 35 mg;
  • dark chocolate bar (100 g) - 80 mg;
  • milk chocolate bar (100 g) - 25 mg;
  • jar of energy drink - 55 mg.

Thus, it cannot be denied that citramon is able to increase blood pressure. Two tablets of citramone is already more than a sufficient dose in order to qualitatively affect vascular tone and blood pressure indicators.

Does citramon increase blood pressure?

Based on the foregoing, the following conclusions can be drawn:

  • if there is a tendency of the body to hypertension, citramon can help increase pressure;
  • if a person regularly consumes caffeine, then he develops an “addictive” effect, in which a citramone tablet may not affect pressure in any way;
  • if a person suffers from low blood pressure, then citramon normalizes pressure, increasing its performance. True, for this it is recommended to drink 2 tablets at once.

So does citramone increase blood pressure? In most cases, yes.

Citramon at low pressure

Purposeful regular use of Citramon at low pressure and for its prevention is recognized as not entirely correct, since regular use of caffeine increases the risk of diseases of the cardiovascular system.

It is not recommended to stimulate the body by drinking coffee and frequent intake of caffeine-containing tablets. First of all, you should find out the reason for the decrease in pressure indicators. Hypotension can be caused by diseases such as vegetovascular dystonia, poor myocardial function, post-infarction condition, congenital heart disease, physical overload of the body (chronic fatigue syndrome), etc.

Of course, if you take 1-2 tablets of citramone for a headache, nothing bad will happen. But taking pills without special need, and also just for the prevention of low blood pressure, should not be.

Citramon at high pressure

The caffeine present in citramone stimulates processes in the brain and even improves mood, however, frequent intake of citramone by persons prone to hypertension can lead to high blood pressure. For example, taking 2 or 3 tablets of Citramon at a time can lead to vasospasm and an increase in blood pressure.

Of course, if the body is "adapted" to a constant dose of caffeine, then citramone tablets may not affect the pressure indicators in any way. However, experiments with one's own health should not be carried out independently: this requires strict medical supervision.

Let's sum up a little: is citramon harmful when high pressure? Yes, it affects negatively if a person already has problems with pressure. If the pressure is stable and within the normal range, then, most likely, after taking citramone, it will remain so.

If the pressure is low, then taking the Citramon tablet normalizes the pressure, raising it to normal levels.

We think we have fully answered this question. Be healthy!

Citramon is a well-known drug that is often used to relieve headaches. It can be drunk to increase pressure, and the drug is contraindicated for hypertensive patients.

Blood pressure can fluctuate many times during the day. It is associated with physical and emotional stress. Normally, such jumps do not bring discomfort to a person, since the change is insignificant. But if at the same time a headache and other symptoms appear, then we can talk about a significant change in blood vessels, hypertension. Often people drink Citramon when they have a headache. But there are cases in which the medicine does not help or, conversely, the pain becomes even more intense. Citramon and pressure are interconnected, but this drug raises or lowers the pressure, you can accurately answer by considering the composition and mechanism of its action on the body.

Citramon tablets in their composition have acetylsalicylic acid, paracetamol. Based on the composition, you can understand whether this drug increases or lowers the pressure.

Caffeine stimulates the work of the heart muscle, increasing the number of heart contractions, thus speeding up the movement of blood through the arteries. In addition, it increases vascular tone.

Acetylsalicylic acid has the ability to reduce the density of blood, thins it, thereby contributing to its free movement along the vascular bed. Paracetamol is used to relieve inflammation, as well as to reduce body temperature. With a headache, paracetamol relieves inflammation of the blood vessels and pain.

The benefits and harms of citramone

When a headache occurs, it is imperative to measure the pressure in order to know whether citramon can be drunk. If vascular hypertension is diagnosed, then Citramon should not be taken at elevated pressure. Indeed, with hypertension, patients are prohibited from coffee containing caffeine, since the drink can provoke a new attack. The composition of the drug contains a lot of caffeine, so you can not drink citramon with high blood pressure. In this case, it will not only not help, but will also lead to an increase in headache and other manifestations characteristic of arterial hypertension:

  • flushing of the face;
  • panic state;
  • tremor;
  • increased sweating;
  • heart pain.

Citramon under pressure has a positive effect when it comes to hypotension. With low pressure, people feel tired, sleepy. In addition, the following symptoms are observed:

  • pallor;
  • nausea;
  • dizziness;
  • headaches in the frontal and temporal region;
  • lack of coordination;
  • noise in ears;
  • visual impairment.


All these symptoms lead to a decrease in vitality and human performance. When such symptoms appear, you should definitely consult a doctor. If this is not immediately possible, then vascular hypotension is removed with citramon. In this case, you need to take 2 tablets of the drug.

Citramon at low pressure helps to increase vascular tone, which leads to an increase in blood pressure.

Citramon at reduced pressure increases the force of contraction of the heart muscle. This leads to the fact that more blood flows to the brain, and its supply of oxygen increases. After taking this medicine, patients with hypotension feel much better, so they often use Citramon to increase pressure.

Indications and contraindications for use

Since citramon affects blood pressure, it is taken for headaches associated with a decrease in blood pressure. It is also used in the following conditions:

  • toothache;
  • muscle pain;
  • painful menstruation.

The composition of citramone includes, which relieves fever and pain. Therefore, the drug is used for acute respiratory infections, influenza, accompanied by body aches, fever, headache.

Like other medicines, citramon has its own contraindications. The main thing not to do is to take Citramon at high pressure. Many people do not know whether this medicine raises or lowers blood pressure in vascular hypertension, therefore, with high tonometer readings, the use of the drug does not bring the desired relief, but, on the contrary, aggravates the situation. This means that you must take the medicine under the control of blood pressure.


There are other diseases in which the use of the drug should be carried out with caution or its use is generally prohibited:

  • endocrine diseases (diabetes mellitus);
  • decreased blood clotting;
  • diseases of the gastrointestinal tract (ulcer, gastritis with high acidity);
  • severe diseases of the liver and kidneys;
  • cardiac ischemia;
  • allergies to any component of the drug.

In addition, its use in the period before surgery is undesirable, since the drug thins the blood and reduces its clotting. This can lead to bleeding. It is forbidden to drink medicine to children under 15 years of age. During pregnancy and lactation, Citramon should also not be taken.

When taking this drug, you may experience side effects:

  • dyspeptic disorders;
  • skin allergic rashes;
  • blurred vision;
  • noise in ears;
  • blood clotting disorder.

To avoid such complications, before using the pills, you need to consult a doctor about the advisability of such treatment. When taking the medicine, you must strictly observe the doses indicated in the instructions for use.

Conclusion

Given the above, we can conclude that citramone tablets increase blood pressure. In this case, he provides positive result: relieves drowsiness and headache.

But when taking citramon, it should be remembered that it contains acetylsalicylic acid, which negatively affects the digestive organs. Therefore, you need to take the medicine after eating and drink plenty of water.

With long-term treatment with citramon, medical supervision is needed. During this period, the doctor monitors changes in the blood test, blood pressure and decides on the advisability of further treatment with this drug.


Lactating


Children under 15


For gastritis or ulcers


With severe arterial hypertension (high blood pressure)


After drinking alcohol


For insomnia (sleep disorders)


With glaucoma


Caution in liver disease


Impressive, huh?
And how do you like people's thoughts about citramone: your head hurts - take citramone - it will help anyone - and if it doesn't help, it won't hurt; menstruation interferes with living with pain - citramone, citramone - this is the safest medicine, take citramone for a cold, and so on, yesterday you had a good rest - it will help again, drinking citramone often is not dangerous, it helps from everything if the child - then half a tablet, a quarter for a cat. Sounds like what you think of citramone? If not you, then your acquaintances, friends, parents. I'm just scared of people who come to the pharmacy and take 10-20 packs at once - this means that they drink it all the time. It is especially a pity for pregnant women, who only by the end of the term find out that citramon is contraindicated for pregnant women.
Read.
Let's figure out what citramon is, is it useful or harmful.
So, the truth about Citramon

1) What is included in the composition of citramon

The composition of citramon includes, and. Different manufacturers call this drug differently and slightly vary the amount of active ingredients:

2) What are the indications for taking Citramon:

Pain syndrome of mild and moderate severity (of various origins):




  • headache;
  • migraine;
  • toothache;
  • neuralgia;
  • myalgia;
  • arthralgia;
  • algomenorrhea.
  • febrile syndrome with acute respiratory infections and influenza

3) To whom citramon is contraindicated:


  • hypersensitivity
These are various allergic reactions on any substance that is part of Citramon, including not only active, but also auxiliary substances

  • uh rozivno-ulcerative lesions of the gastrointestinal tract(in the acute phase)
For any gastritis-like pain, the drug is contraindicated, especially if you have gastritis or a stomach ulcer or intestinal ulcer in the acute (unhealed) phase. Even when using aspirin in low doses - 75-300 mg / day (as an antiplatelet agent) - aspirin can cause damage to the gastric mucosa and lead to the development of erosions and / or ulcers, which are often complicated by bleeding. The risk of bleeding is dose-dependent: when administered at a dose of 75 mg / day, it is 40% lower than at a dose of 300 mg, and 30% lower than at a dose of 150 mg. Even slightly, but constantly bleeding erosions and ulcers can lead to a systematic loss of blood in the feces (2-5 ml / day) and the development of iron deficiency anemia.

  • gastrointestinal bleeding
The first sign is a change in the color of feces to dark

  • "aspirin" asthma
Characteristic for some asthmatics: a variant of endogenous or mixed bronchial asthma in which one of the factors contributing to the narrowing of the bronchi are non-steroidal anti-inflammatory drugs (NSAIDs), including acetylsalicylic acid; consists of a triad of symptoms: polyposis rhinosinusitis, asthma attacks and intolerance to NSAIDs

  • hemophilia
Hereditary disease associated with impaired coagulation (the process of blood clotting); with this disease, hemorrhages occur in the joints, muscles and internal organs, both spontaneously and as a result of trauma or surgery. With hemophilia, the risk of a patient's death from hemorrhage increases sharply, even with a minor injury, since it is very difficult to stop it (weak blood clotting).

  • hemorrhagic diathesis
TO hemorrhagic diathesis include diseases based on violations of the vascular wall and various parts of the hemostasis system, causing increased bleeding or a tendency to its occurrence. On the globe, about 5 million people suffer from primary hemorrhagic manifestations. Given that secondary hemorrhages, such as DIC in the pre-agonal state, are not always fixed, one can imagine the prevalence of hemorrhagic diathesis.

  • hypoprothrombinemia
Deficiency of the clotting factor prothrombin in the blood, as a result of which a person has an increased tendency to bleed. Hypoprothrombinemia may be hereditary or may develop as a result of any liver disease, vitamin K deficiency in the body, or the use of anticoagulants in the treatment of another disease.

  • portal hypertension
It's a syndrome high blood pressure in the portal vein system caused by impaired blood flow in the portal vessels, hepatic veins and inferior vena cava. In most cases, portal hypertension is a consequence of cirrhosis of the liver, schistosomiasis (in endemic areas), structural abnormalities of the hepatic vessels.

  • beriberi K
Vitamin K deficiency may develop due to intestinal malabsorption (such as bile duct obstruction), therapeutic or accidental absorption of vitamin K antagonists, or, very rarely, dietary vitamin K deficiency. As a result of acquired vitamin K deficiency, Gla-radicals are not completely formed, as a result of which Gla-proteins are not fully perform their functions. The above factors can lead to the following: profuse internal hemorrhages, cartilage ossification, severe deformation of developing bones, or salt deposits on the walls of arterial vessels.

  • kidney failure
With prolonged use of paracetamol more than 1 tablet per day (1000 or more tablets in a lifetime), the risk of developing severe analgesic nephropathy, leading to terminal kidney failure. It is based on the nephrotoxic effect of paracetamol metabolites, especially para-aminophenol, which accumulates in the renal papillae, binds to SH-groups, causing severe violations of the function and structure of cells, up to their death. At the same time, the systematic use of aspirin is not associated with such a risk. Thus, paracetamol is more nephrotoxic than aspirin and should not be considered a "perfectly safe" drug.

  • pregnancy (I and III trimesters)
Citramon is contraindicated in the 1st and 3rd trimesters of pregnancy due to its constituent acetylsalicylic acid. And caffeine, which is part of citramon, enhances the effect of acetylsalicylic acid. Acetylsalicylic acid or aspirin has a teratogenic effect on the fetus; with prolonged use in the first trimester, it can lead to a malformation - splitting of the upper palate; in the III trimester - to inhibition of labor activity, to the closure of the arterial duct in the fetus, which causes hyperplasia of the pulmonary vessels and hypertension in the vessels of the pulmonary circulation. Citramon causes increased bleeding due to impaired platelet aggregation and inhibition of prothrombin synthesis in the liver, which during childbirth is dangerous with severe bleeding.

  • lactation (breastfeeding)
Acetylsalicylic acid, which is part of citramon, is excreted with breast milk, which increases the risk of bleeding in a child due to impaired platelet function, can also lead to, therefore, maternal acetylsalicylic acid should not be used during lactation.
Paracetamol is excreted in breast milk: the content in milk is 0.04-0.23% of the dose taken by the mother, paracetamol is contraindicated in the neonatal period.

  • glucose-6-phosphate dehydrogenase deficiency
Patients develop hereditary nonspherocytic hemolytic anemia varying severity.

  • severe arterial hypertension
The incidence of arterial hypertension in Russia among men is 39.2%, among women - 41.1%. However, 58% of women and 37.1% of men are informed about their illness, drug treatment is carried out in 45.7 and 21.6% of cases, respectively. The therapy is effective only in 17.5% of women and 5.7% of men.
The incidence of arterial hypertension increases as the age of patients increases. In Russia, approximately 80% of people over the age of 65 are diagnosed with elevated levels HELL. In the world, this figure reaches 60%. Approximately 65 million people in the United States suffer from arterial hypertension. At the same time, only 79% are aware of their illness. Courses of treatment are 59% of patients.

  • severe course of coronary artery disease
Ischemic disease heart disease (IHD) is a pathological condition characterized by an absolute or relative violation of the blood supply to the myocardium due to damage to the coronary arteries of the heart. Ischemic heart disease is a myocardial lesion caused by a disorder of the coronary circulation, resulting from an imbalance between coronary blood flow and metabolic needs of the heart muscle. In other words, the myocardium needs more oxygen than it receives from the blood. IHD can occur acutely (in the form of myocardial infarction), as well as chronically (periodic attacks of angina pectoris)

  • glaucoma
The incidence of glaucoma in adults is 1-1.5 cases per 100 people.

  • hyperexcitability
Caffeine, which is part of citramone, increases nervous excitability

  • sleep disorders
Insomnia often occurs in older people, caffeine, which is part of citramone, aggravates insomnia

  • surgical interventions accompanied by bleeding
Before surgery, to reduce bleeding during surgery and during postoperative period you should stop taking salicylates for 5-7 days.

  • childhood
Up to 15 years - the risk of developing Reye's syndrome in children with hyperthermia on the background of viral diseases.
Reye's syndrome - develops when aspirin is prescribed (part of citramon) to children with viral infections (flu, chicken pox). Presents with severe encephalopathy, cerebral edema, and liver damage that occurs without jaundice but with high level cholesterol and liver enzymes. Gives very high lethality (up to 80%). Therefore, aspirin should not be used for acute respiratory viral infections in children of the first 12 years of life.
Overdose or poisoning in mild cases is manifested by symptoms of "salicylism": tinnitus (a sign of "saturation" with salicylate), stupor, hearing loss, headache, visual disturbances, sometimes nausea and vomiting. In severe intoxication, disorders of the central nervous system and water-electrolyte metabolism develop. There is shortness of breath (as a result of stimulation of the respiratory center), acid-base disorders (first respiratory alkalosis due to loss of carbon dioxide, then metabolic acidosis due to inhibition of tissue metabolism), polyuria, hyperthermia, dehydration. Myocardial oxygen consumption increases, heart failure, pulmonary edema may develop. The most sensitive to the toxic effect of salicylate are children under 5 years of age, in whom, as in adults, it manifests itself as severe disorders of the acid-base state and neurological symptoms. The severity of intoxication depends on the dose of aspirin taken (Table 6).
Mild to moderate intoxication occurs at 150–300 mg/kg, 300–500 mg/kg leads to severe poisoning, and doses greater than 500 mg/kg are potentially lethal.

4) Who needs to take Citramon with caution:


  • gout
Acetylsalicylic acid, even in small doses, reduces excretion uric acid from the body, which can cause an acute attack of gout in predisposed patients.

  • liver disease
Paracetamol is hepatotoxic when taken in very high doses. Its simultaneous administration at a dose of more than 10 g in adults or more than 140 mg / kg in children leads to poisoning, accompanied by severe liver damage. The reason is the depletion of glutathione reserves and the accumulation of intermediate products of the metabolism of paracetamol, which have a hepatotoxic effect. IN last years data appeared on the hepatotoxic effect of paracetamol with its moderate overdose, with the appointment of paracetamol in high therapeutic doses and simultaneous use of inducers of the microsomal enzyme system of the liver P-450 (antihistamines, glucocorticoids, phenobarbital, ethacrynic acid), as well as in alcoholics.

  • when taken with alcohol
Even when taken in therapeutic doses (1.5 g / day, according to GF X), paracetamol can cause serious liver damage in alcoholics, as well as in persons who systematically drink alcohol (for men - a daily intake of more than 700 ml of beer or 200 ml of wine, for women - doses are 2 times less), especially if paracetamol was taken after a short period of time after drinking alcohol. With the simultaneous use of aspirin with ethanol (alcohol), the effect of acetylsalicylic acid on the gastrointestinal tract may be enhanced.
Think about how often, how many times a week do you while away the evening with a bottle of beer? And so - taking citramone, as a remedy for a hangover, is very harmful to your liver. In various kinds of advice on the Internet, how to get rid of a morning hangover, advice such as take a citramone tablet + a paracetamol tablet is far from the last place. And many practice to drink coldrex maxigripp or teraflu extra (the maximum possible content of paracetamol) from a hangover. Helps, I do not argue - but at what cost?
With prolonged use of paracetamol more than 1 tablet per day (1000 or more tablets per life), the risk of developing severe analgesic nephropathy, leading to terminal renal failure, doubles.
Caffeine, like other CNS stimulants, is contraindicated in hyperexcitability, insomnia, severe hypertension and atherosclerosis, with organic diseases of cardio-vascular system, in old age, with glaucoma.

Conclusions:

I do not protest against taking citramone for pain - it is good remedy. But you need to use it with an eye on contraindications and make sure that it does not become a habit, that citramone does not become a panacea for all types of misfortunes. And please - do not give Citramon to children and pregnant women!
_________________________________________________________

Question:

Good afternoon Please tell me, is it possible to drink Citramon from a headache at an early stage of pregnancy? And if not, what is still possible?
And one more question: I drank the antibiotic Augmentin in the first or second week of pregnancy (I didn’t know that I was pregnant). The contraindications say that pregnant women should not. Tell me, how dangerous is this in my case? Can this really harm the baby? This issue is very worrisome. Thank you in advance.

Answer:

Citramon is contraindicated in the 1st and 3rd trimesters of pregnancy due to its constituent acetylsalicylic acid. And caffeine, which is part of citramon, enhances the effect of acetylsalicylic acid. Acetylsalicylic acid or aspirin has a teratogenic effect on the fetus; with prolonged use in the first trimester, it can lead to a malformation - splitting of the upper palate; in the III trimester - to inhibition of labor activity, to the closure of the arterial duct in the fetus, which causes hyperplasia of the pulmonary vessels and hypertension in the vessels of the pulmonary circulation. Thus, taking Citramon during pregnancy is contraindicated. If you have frequent headaches during pregnancy, you need to find out their cause. Paracetamol can be used for migraine headaches, as well as tension headaches (with the permission of your doctor). From painkillers, you can also take No-shpu.
Augmentin during pregnancy is taken with caution and under the supervision of your doctor. Amoxicillin, which is part of Augmentin, does not have a teratogenic effect. In several studies that I found mention of, there was no adverse effect of amoxicillin / clavulanate (Augmentin) on the fetus when using the drug in pregnant women in the first trimester.
At your next visit to the doctor who is managing your pregnancy, be sure to tell him about the drugs you are taking. medicines at an early date. He will prescribe additional studies that will help eliminate the possibility of malformations.

Question:

Unfortunately, paracetamol and no-shpa do not help at all with my frequent severe headaches (ultrasound of the vessels of the head, tomography, and other studies did not reveal the cause of the migraine). I have been married for four years, but I am afraid of getting pregnant precisely because of a migraine. The first pregnancy was unsuccessful (at the 6th week there was a miscarriage after taking two tablets of Citramon). Help, please, in my case.

Answer:

I can't recommend anything new. Of the analgesics for migraine during pregnancy, only paracetamol (acetaminophen) can be used in small doses in the 1st and 2nd trimesters. In the 3rd trimester, it is contraindicated. Other analgesics are contraindicated. If paracetamol does not help you, try combining it with caffeine (how to take it is described below). Citramon should not be taken during pregnancy. The component of citramon that could cause a miscarriage is acetylsalicylic acid. It is contraindicated in the 1st and 3rd trimester.
It is necessary to identify patterns in the appearance of migraine - perhaps this is a reaction to the following factors: stress, nervous and physical overexertion, nutritional factors (cheese, chocolate, nuts, fish), alcohol (most often beer and red wine, champagne), hormonal causes (menstrual cycle, taking contraceptives), sleep (lack or excess), weather factors (change of weather, change of climatic conditions). Try to avoid these factors.
With migraine, intestinal motility slows down and is often accompanied by nausea, sometimes vomiting. With nausea and vomiting that accompanies an attack, you can take cerucal (metoclopramide) - but it is contraindicated in the 1st trimester of pregnancy. Due to the slowing down of the intestines, it is recommended to take migraine medications in combination with caffeine, which facilitates the absorption of drugs and accelerates their action. Caffeine sodium benzoate for normal patients is prescribed 200 mg during an attack of pain, then 100 mg 2-3 times a day for several days. I have not found any serious contraindications for pregnant women. But the dose definitely needs to be reduced. Consult with your doctor. Sometimes papazol also helps. It is not contraindicated in pregnant women.

Question:

Hello! I was in the clinic, I had a miscarriage, doctors allowed all pregnant women to have citramone for headaches, I thought it was harmless, I’m now 4 weeks pregnant, I drank 10 pills during these 4 weeks, of course not every day, how serious is it?

Answer:

The instructions for the drug Citramon clearly state that it is contraindicated in the first and third trimester of pregnancy, as well as during breastfeeding. Acetylsalicylic acid, which is part of Citramon, has a teratogenic effect, so taking the drug in the first trimester of pregnancy is strictly prohibited, in order to avoid the occurrence congenital anomalies fetal development. Why some doctors allow him to take it is not clear to me. When planning conception and pregnancy, before taking any drug, be sure to read the instructions (contraindications) even for the simplest and most well-known drugs in your opinion. Because otherwise you can take something harmful to the unborn baby. Try to take less medicines, even those allowed according to the instructions. How serious it is for your unborn child to take citramone in the first trimester can only be found out by your doctor who leads the pregnancy. Tell him as soon as possible about the fact of taking Citramon.

Citramon belongs to the group of non-narcotic drugs, analgesics. It's complex medical device, the active ingredients of which are a compound of paracetamol, caffeine and acetylsalicylic acid.

Due to the complex effect, the drug has an anti-inflammatory, analgesic, analgesic, vasodilating effect on the centers of inflammation. Citramon is used to reduce the effects of various pains of low intensity - headaches, toothaches, muscle aches, periodic spasms.

It is also actively used in febrile conditions during influenza. To understand what the drug helps with and when it is prescribed, you need to consider its composition and action.

Clinical and pharmacological group

Analgesic-antipyretic combined composition.

Terms of sale from pharmacies

Can buy without a doctor's prescription.

Price

How much does Citramon cost in pharmacies? The average price is at the level of 11 rubles.

Composition and form of release

To date, the number of manufacturers of the drug is steadily growing, so the composition of Citramon will be slightly different. However, the main active substance is not subject to change.

The composition of Citramon "classic" included:

  • 0.25 g of acetylsalicylic acid (Acidum acetylsalicylicum);
  • 0.17 g phenacetin (Phenacetini);
  • 0.027 g caffeine (Caffeine);
  • 0.021 g of citric acid (Citric acid);
  • and 0.014 g cocoa.

This composition has now ceased to exist, and phenacetin was banned, as it can cause serious complications and side effects. Most often, the composition of the combined drug now includes the main three components:

  • aspirin (Acidum acetylsalicylicum);
  • paracetamol (Paracetamoli);
  • and caffeine.

Different types of Citramon

Depending on the manufacturer, Citramon comes with a different composition and name. To date, the following varieties are produced:

  • Citramon P - contains aspirin, caffeine and paracetamol. The use of Citramon P is contraindicated in persons under 14 years of age. The dosage for adults is 1 to 2 tablets three times a day. There should be a gap between doses (at least 6 hours).
  • Citramon Forte - contains, in addition to aspirin, caffeine and paracetamol, as well as citric acid. Auxiliary components: cocoa, potato starch, magnesium stearate. The addition of citric acid to the drug is not accidental; it stabilizes cellular respiration at the biochemical level. Assign Citramon Forte to persons aged 14 years and above, the dosage is 1-2 tablets up to three times a day.
  • Citramon Darnitsa is the most popular among the rest. The composition includes aspirin, paracetamol, caffeine, citric acid. Auxiliary components: starch, cocoa, calcium stearate and polyvinylpyrrolidone. The rules of application do not differ from previous drugs.
  • Citramon Ultra - consists of acetylsalicylic acid, paracetamol and caffeine. Available in the form of capsules, appoint 1-2 capsules up to a maximum of four times a day. The daily dose should not exceed eight capsules.

Pharmacological effect

Citramon is combined medication and its therapeutic effect is due to the properties active components included in its composition:

  1. Paracetamol has antipyretic and analgesic properties, as well as a moderately pronounced anti-inflammatory effect.
  2. Acetylsalicylic acid has antipyretic and anti-inflammatory properties, and this substance also relieves pain caused by inflammation and reduces blood clotting, thereby stimulating blood circulation in the inflammation site.
  3. Caffeine produces an exciting effect on the central nervous system and stimulates the work of the psychomotor centers of the central nervous system. It increases the lumen of blood vessels and reduces the feeling of drowsiness and fatigue. Caffeine is also known for its stimulating effect on physical and mental activity. It has caffeine and a mild analgesic effect.

Citramon raises or lowers blood pressure?

This question is often asked by patients. Due to the content of caffeine, which stimulates the central nervous system, increases tone and pressure, pressure can also increase from taking Citramon, despite the fact that it is contained in small doses. Moreover, you should be careful if you drink tea, cocoa or coffee and take Citramon - there is a risk of an overdose of caffeine. If you have low blood pressure and suffer from a headache, then in the absence of contraindications, you can take a Citramon tablet, which will relieve pain and slightly increase blood pressure.

Indications for use

Basically, these are mild and moderate pains of various locations:

  • headache;
  • migraine;
  • pain during menstruation;
  • neuralgia;
  • pain in the joints and muscles;
  • increased body temperature with influenza, colds and rheumatic diseases.

WITH severe pain Citramon is unlikely to cope, therefore, in more difficult cases recommended means that have these effects to a greater extent.

Citramon for headaches

For headaches, this is one of the most effective remedies that is usually found in the medicine cabinet. The combination of its components provides a fairly quick action - the elimination of pain, increased mental activity and performance. He copes with pain of various etiologies, including migraines. Not being a narcotic medicine, it does not cause addiction and dependence.

It is only undesirable to mix Citramon with other drugs against headaches - such issues should be discussed with the doctor.

Contraindications

Absolute:

  • glaucoma;
  • hemophilia and other blood clotting disorders;
  • operations that are accompanied by heavy bleeding;
  • simultaneous reception of methotrexate in an amount of more than 15 mg per week;
  • sleep disturbance, increased nervous excitability;
  • deficiency of glucose-6-phosphate dehydrogenase;
  • gastrointestinal bleeding or perforation;
  • erosive and ulcerative lesions of the gastrointestinal tract (GIT) in the acute phase;
  • history of peptic ulcer;
  • hypoprothrombinemia, hemorrhagic diathesis;
  • portal hypertension;
  • avitaminosis K;
  • chronic heart failure III and IV functional class according to the classification of the New York Heart Association (NYHA);
  • arterial hypertension (III degree);
  • incomplete or complete combination of bronchial asthma, recurrent polyposis of the paranasal sinuses and nose, as well as intolerance to non-steroidal anti-inflammatory drugs (NSAIDs), for example, ASA;
  • severe hepatic and / or renal failure;
  • During pregnancy and breastfeeding;
  • age up to 18 years (with febrile syndrome) or up to 15 years (with pain syndrome);
  • hypersensitivity to the components of Citramon P.

The drug is prescribed with caution in the following cases:

  • chronic heart failure (I and II functional class according to NYHA);
  • epilepsy, tendency to convulsive seizures;
  • simultaneous use of methotrexate in an amount of less than 15 mg per week, as well as glucocorticosteroids, NSAIDs, antiplatelet agents, anticoagulants, selective inhibitors serotonin reuptake;
  • alcoholism;
  • renal and / or hepatic insufficiency of moderate and mild degree;
  • chronic obstructive pulmonary disease;
  • gout;
  • cardiac ischemia;
  • cerebrovascular diseases;
  • peripheral arterial disease;
  • smoking;
  • elderly age.

Appointment during pregnancy and lactation

During pregnancy (I and III trimesters) and during breastfeeding, the drug is contraindicated. In the second trimester of pregnancy, the drug should be used with caution, balancing the intended benefit to the mother and the potential risk to the fetus.

Dosage and method of application

As indicated in the instructions for use, Citramon tablets are intended for oral administration, preferably after meals. The average therapeutic dosage for adults and adolescents over 15 years of age is 1-3 tablets 2-3 times a day, depending on the severity of pain or fever.

The maximum daily dosage should not exceed 6 tablets. The drug is not intended for a long course of therapy, the maximum duration of taking tablets should not exceed 5 days.

Adverse reactions

Side effects of Citramon:

  • increased blood pressure, arrhythmia, tachycardia;
  • aggravation of heart failure, manifestation of its latent forms (with prolonged use);
  • dizziness, insomnia, agitation, anxiety, headache, tinnitus, hearing and vision impairment, aseptic meningitis;
  • gastralgia, anorexia, nausea, the formation of erosions and ulcerative elements on the mucosa of the digestive canal, gastric and intestinal bleeding;
  • liver failure;
  • hypersensitivity reactions (including the development of symptoms of the Fernand-Vidal triad);
  • interstitial nephritis, nephrotic syndrome, necrotic papillitis, with prolonged use - renal failure;
  • anemia, thrombocytopenia, leukopenia;
  • acute fatty hepatosis, toxic hepatitis, acute hepatic encephalopathy (Reye's syndrome);
  • development of tolerance and weak psychological dependence (with prolonged use of high doses of the drug);
  • drug headache after the abolition of Citramon (if the drug has been used for a long time).

In animal experiments, the teratogenic effect of the drug on the fetus was also proven.

Overdose symptoms

Overdose symptoms include nausea, vomiting, dizziness, epigastric pain. In severe cases, drowsiness, lethargy, loss of consciousness, convulsions, bronchospasm, bleeding, shortness of breath are noted.

If these signs appear, you should immediately seek medical help.

Treatment includes gastric lavage, enterosorbents, saline laxative. Forced alkaline diuresis, alkalizing agents, measures to restore bcc and acid-base balance are shown.

special instructions

Before you start using the drug, read the special instructions:

  1. In patients with a predisposition to the accumulation of uric acid, taking the drug may provoke an attack of gout.
  2. During the reception, you should refrain from drinking alcohol (increased risk of gastrointestinal bleeding and toxic liver damage).
  3. Acetylsalicylic acid slows down blood clotting. If the patient is to undergo surgery, the doctor should be warned about taking the drug.
  4. With prolonged use of the drug, monitoring of peripheral blood and functional state liver.
  5. Patients with hypersensitivity or with asthmatic reactions to salicylic acid and its derivatives, including acetylsalicylic acid, can be prescribed only with special precautions (in the emergency room).
  6. Acetylsalicylic acid has a teratogenic effect; when used in the first trimester, it leads to a malformation - splitting of the upper palate; in the III trimester - to inhibition of labor activity (inhibition of Pg synthesis), to the closure of the arterial duct in the fetus, which causes hyperplasia of the pulmonary vessels and hypertension in the vessels of the pulmonary circulation. It is excreted in breast milk, which increases the risk of bleeding in a child due to impaired platelet function.

Children under 15 years of age should not be prescribed drugs containing acetylsalicylic acid, since in the case of a viral infection they can increase the risk of Reye's syndrome. Symptoms of Reye's syndrome are prolonged vomiting, acute encephalopathy, liver enlargement.

Compatibility with other drugs

When using the drug, it is necessary to take into account the interaction with other drugs:

  1. Caffeine accelerates the absorption of ergotamine.
  2. With the simultaneous administration of the drug and alcohol-containing liquids, the risk of toxic liver damage increases.
  3. Enhances the effect of heparin, indirect anticoagulants, reserpine, steroid hormones and hypoglycemic medicines.
  4. Barbiturates, rifampicin, salicylamide, antiepileptic drugs and other stimulants of microsomal oxidation contribute to the formation of toxic paracetamol metabolites that affect liver function.
  5. Simultaneous use with other non-steroidal anti-inflammatory drugs, methotrexate increases the risk of side effects.
  6. Reduces the effectiveness of spironolactone, furosemide, antihypertensive drugs, as well as anti-gout drugs that promote the excretion of uric acid.
  7. Metoclopramide accelerates the absorption of paracetamol. Under the influence of paracetamol, T1 / 2 of chloramphenicol increases 5 times. When taken repeatedly, paracetamol may enhance the effect of anticoagulants (dicoumarin derivatives).

But is it right? Is citramon harmful? Let's find out.

Is citramon dangerous?

Like any other medicine, before using Citramon, you must read the instructions and indications for use. Turns out it has a few side effects. But let's go in order.

Citramon contains: caffeine, vitamin C, acetylsalicylic acid and paracetamol (the main active ingredient). This combination allows you to achieve the fastest possible relief of mild to moderate headaches. moderate. Citramon can also help with pain in the muscles and joints, and even with severe toothache. And due to the ability to reduce body temperature, it can be taken with colds.

However, not everyone can drink Citramon and not always. Pregnant women should take these pills with extreme caution. This is due to the fact that aspirin, which is part of the drug, can adversely affect the development of the fetus, as well as worsen blood clotting. Nursing mothers should consult with their doctor before using Citramon. Children under 15 years of age are also at risk and it is not advisable for them to be allowed to drink these pills.

If you have gout or the doctor speaks of poor blood clotting, it is better to refrain from using citramone so as not to harm your body. Problems with internal organs (in particular, the liver and kidneys) are also a reason to think about the harmful effects of citramone on health.

Thus, the question of whether citramon is harmful to health can be answered as follows - it certainly harms the body with frequent and prolonged use, but there are situations when it quickly relieves pain and alleviates the patient's lot.

What are the symptoms and consequences of an overdose of Citramon?

Citramon can bring many benefits in certain life situations. But, as with any medicine, harm to the body is not ruled out if it is strongly carried away. Therefore, it is necessary to know what symptoms and consequences of an overdose may occur with uncontrolled use of the drug.

After all, a dangerous overdose of Citramon occurs when more than ten tablets of the drug are consumed during the day, or six tablets in the case of a single dose.

It is quite common, often used, as it is widely known, and at the same time it is really able to save a person from the occurrence discomfort and if you feel unwell after drinking alcohol, a hard day's work or a long stay in a stuffy room.

Compound

The drug Citramon owes its positive properties to a balanced combination of acetylsalicylic acid, caffeine and paracetamol. Each separately given component is aimed at improving the blood circulation of the brain:

  1. Caffeine enhances blood flow, stimulates the work of the myocardium, speeds up heart contractions, increases the minute pumped blood volume.
  2. Acetylsalicylic acid (brand name "Aspirin" - under this name the drug is best known among consumers) promotes blood thinning, which makes it possible to significantly increase the transport of oxygen through the vessels of the brain, providing intensive metabolism, as well as the timely removal of decay products that cause pain .
  3. Paracetamol is a pronounced non-narcotic analgesic that has a strong anti-inflammatory effect, relieves pain syndrome varying degrees severity, is a stimulant that does not affect the process and course of the disease, but leveling the vivid symptoms.

Special purpose

Citramon is used quite widely, especially by those who have experienced its fairly effective effect, that is, real benefit. Reviews among specialists about the drug are positive, and it is recommended for use (single or systematic treatment) in the following situations:

  • It is prescribed and used as an analgesic for the relief of headaches, relieving acute toothache, and for joint (rheumatic) inflammation.
  • It is used during the treatment of colds, influenza manifestations - as a means to reduce body temperature.
  • It is used for overwork in people of mental labor to treat symptoms of fever of the face, dizziness from prolonged monotonous work, with confusion during a change of scenery - going out into a crowded place, speaking to an audience, conducting lengthy negotiations.
  • Involved in the treatment system inflammatory diseases: arthritis, arthrosis (their exacerbations), rheumatism, otitis media, sinusitis, rhinitis, vascular spasms and acute conditions in infectious diseases.
  • Assign in cardiology, as a means for the prevention of thrombosis and sclerosis of the coronary vessels of the heart; in angiology, as a means for the prevention of cerebral ischemia. For these purposes, they are used in short courses to prevent poisoning with Citramon, and when complex conditions improve, for long-term treatment acetylsalicylic acid is used in combination with magnesium and potassium salts.

Possibility of overdose, consequences

However, the drug Citramon, which is quite complex in composition, is commercially available. Prescription documents are not required when purchasing it in a pharmacy network, and there are no restrictions on the amount of the drug sold for one buyer.

However, in such an uncontrolled and free style of offering, using and distributing the drug, there is a certain danger - the possibility of poisoning. This can happen when an overdose of Citramon occurs, with prolonged use of the drug and, especially, with its inept use.

By using the drug, a person has the right to know that at certain doses it is harmful, that there is an established therapeutic dose of Citramon, and that negative consequences are possible with its overdose.

Many people ask a reasonable question - is it possible to get poisoned with Citramon? Naturally, this is a medicine that, like any other, can harm the body, and sometimes cause irreversible negative processes in the internal organs.

To relieve pain or as a prophylaxis, a single dose of one tablet is recommended. The same dosage is used for headache and toothache, fever (presence of fever), mild hangover and feeling unwell after drinking any dose of alcohol. Next reception allowed after 6-8 hours. The maximum safe dose is 6 tablets per day.

When using Citramon as an analgesic, the drug is recommended to be used for no more than 5 days in a row, in the amount of 2-3 tablets per day; when used to reduce fever, reduce temperature - the drug is used for 3 days in the above dosage.

Manifestations of an overdose of the drug

When used a large number drug (accidentally or intentionally) the following symptoms and side effects are observed:

  1. Nausea, vomiting, dyspepsia ( liquid stool, diarrhea, spotting with stools, bloating).
  2. Background tinnitus, increasing headache, dizziness.
  3. Symptoms of developing internal bleeding (pallor, weakness, cold sweat, feelings of fear).
  4. Pronounced sweating, tremor, skin cold to the touch.
  5. A disturbance of consciousness develops at a high concentration of the drug in the blood (more than 300 mcg / ml).

To prevent such situations, it is important to conduct timely explanations among young people, who are often addicted to such facilitating methods of getting rid of a hangover and pain in the head. It must be reminded that any drug, even if it is freely sold and inexpensive, can cause irreparable harm even to the strongest and most trained body.

Video: how often can you drink Citramon?

Contraindications

Citramon is a drug that contains dangerous for many chronic diseases Components. Therefore, patients with such ailments should be warned in advance about the possible consequences.

The drug is not used for such diseases:

  • ulcerative intestinal formations in acute form;
  • liver failure ( fatty degeneration, cirrhosis);
  • kidney failure (nephropathy, inflammatory processes);
  • blood diseases (hemophilia, hemorrhagic diseases);
  • vascular thrombosis, thrombophlebitis;
  • acute pancreatitis;
  • severe course of diabetes.

It is necessary to prescribe antihypertensive drugs, monitor blood pressure throughout the day, and ensure compliance with all doctor's recommendations to prevent the development of severe, life-threatening conditions - stroke, heart attack, and blood disorders.

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How does citramon affect the body?

Pharmacological action of "Citramon"

The pharmacological action of "Citramon" is determined by the influence of each active substance that is part of it. Acetylsalicylic acid has an antipyretic and anti-inflammatory effect, relieves the pain symptom caused by inflammation, improves blood circulation at the site of the inflammatory process. Caffeine has a stimulating effect on the central nervous system and psychomotor centers, it expands blood vessels, reduces the feeling of fatigue, drowsiness, has a slight analgesic effect, stimulates physical and mental activity. Paracetamol has an antipyretic, analgesic and moderately pronounced anti-inflammatory effect.

"Citramon" relieves pain syndromes of moderate severity. It helps with headache and toothache, pain in muscles, joints, neuralgia, feverish conditions and painful menstruation. The drug should be taken one tablet three times a day.

Contraindications, side effects of Citramon

"Citramon" is contraindicated in case of increased individual sensitivity, hemophilia, constant high blood pressure, erosive gastritis and peptic ulcer, hemorrhagic diathesis, hepatic or renal failure, with severe atherosclerosis of cerebral vessels and coronary heart disease. Do not give the drug to children under 15 years of age. The drug is contraindicated in preparation for surgical operations because it increases bleeding.

In general, you can not drink "Citramon" in the first and third trimester of pregnancy, since acetylsalicylic acid can lead to the appearance of congenital anomalies of the fetus. In the second trimester, the drug is taken only as directed by a doctor. With a headache, blood pressure should be measured, if it is elevated, Citramon is contraindicated, as it contributes to an even greater increase. You need to lower the pressure with the help of other drugs.

According to reviews, "Citramon" can cause the following side effects: nausea, vomiting, abdominal pain, visual disturbances, the appearance of tinnitus. With prolonged use of the drug, the appearance of erosive gastritis, development of liver disorders, blood clotting disorders, increased headache, dizziness, impaired renal function. "Citramon" can also cause a variety of allergic reactions: skin rash, itching, urticaria, anaphylactic shock, epidermal toxic necrolysis (severe and acute disease affecting skin and mucous membranes).

Citramon is rightfully considered one of the most popular drugs that have come to us since the days of the USSR. At that time, its composition was slightly different, but nevertheless, due to its rapid action and effectiveness, the drug was no less famous. Due to its low cost, it is easy to find in almost every first aid kit. After all, drinking a pill of citramone from the head was a common thing.

A little about the drug

Citramon - what is it, what helps? This non-hormonal agent, relieving inflammation, pain, lowering the temperature. The original formulation of the drug was changed due to the prohibition of phenacetin.

With its help, migraines, toothache and other pain sensations of various genesis are easily removed.

The composition of the drug

IN this moment the medicine is produced by different pharmaceutical companies, so the composition of citramone changes slightly, but the main components remain unchanged.

  • Acetylsalicylic acid. This component of the drug relieves fever and inflammation, anesthetizes, improving blood flow in the focus of inflammation.
  • Paracetamol relieves pain, affects the thermoregulation of the affected area, relieves high temperature. Virtually no anti-inflammatory effect.
  • Caffeine. Thanks to this component of citramone, the feeling of drowsiness is removed, there is an exciting effect on the reflexes of the spinal cord, and the vessels expand.

Produced forms of citramon differ in concentration and proportion active substances, but the mechanism of action on the body is the same.

Action on the body

Like any medicine, citramon brings not only benefits, but also harm to the patient's body. There are a lot of conflicting opinions on the topic of the harm of citramone. Let's try to figure them out.

Expands or narrows blood vessels?

Caffeine selectively acts on the vessels in the body. It dilates the vessels of the muscular corset of the skeleton, the vessels of the kidneys and the heart muscle. And on the vessels of other internal organs and the brain, it acts in a radically opposite way, narrowing them.

Such an effect on the vessels of the brain can put the patient at risk, because long course Citramon treatment may be a prerequisite for stroke.

How does it affect blood pressure?

Citramon affects the patient's blood pressure.

  1. If a person has normal performance pressure, the drug will not have a special effect, and the caffeine contained in its composition will simply dilate the blood vessels.
  2. With a slight increase in pressure parameters, the medicine will not give special effect, and caffeine in its composition can both make blood vessels wider and narrow them.
  3. Citramon at elevated and very high pressure is dangerous to take, because it can lead to a stroke. Such vasoconstriction at elevated pressure can lead to rupture of cerebral vessels. Given the fact that citramone contains aspirin, the blood does not coagulate well. This will make the stroke even more severe.
  4. It is possible to take Citramon if a person suffers from headaches and single pressure rises, but one-time. In this case, the patient should not suffer from hypertensive crisis and constantly high blood pressure.

Watch a video on this topic

Forms of release of the drug

Pharmaceutical companies produce drugs under the brand name "Citramon" with a slightly modified composition.

This form of medicine affects the lowering of the patient's elevated body temperature. With this composition, caffeine improves the effectiveness of acetylsalicylic acid and paracetamol. This drug is not recommended for children under 15 years of age. Dosage for an adult patient: 1-2 tablets two to three times a day.

If there are problems with the kidneys or liver while taking the medicine, then the interval between taking the pills should be at least eight hours.

Citramon-Lect is easy to purchase at any pharmacy kiosk without a doctor's prescription. It contains: acetylsalicylic acid, caffeine and paracetamol. Citramon-Lect is contraindicated for children under 14 years of age. Citramon-Lect should be taken only by adults and adolescents over 14 years of age.

The composition of the drug includes acetylsalicylic acid, caffeine and paracetamol. It is effective for pain of moderate to low intensity. The duration of the course of the drug should not exceed more than 10 days, and the dosage is three to four tablets per day.

The maximum amount of medication per day that a patient should take is 8 tablets.

This medicine is made in the form of capsules with a shell. Inside the granules is a powder of acetylsalicylic acid, caffeine and paracetamol. Dosage of the drug: one or two capsules three to four times a day.

Advantages of Citramon Ultra in comparison with ordinary Citramon:

  • The film that covers the tablets of Citramon Ultra protects the gastric mucosa from irritation. This makes it easier to take the drug for patients suffering from high acidity of the stomach.
  • The packaging of the drug is more convenient than that of ordinary citramone, thanks to the blister.
  • The composition of Citramon Ultra is enriched with paracetamol, which enhances the effect of pain relief and helps to reduce the temperature. Such a medicine is stronger than ordinary citramone.

Citramon-Darnitsa is quite well known for patients. Release form: tablets in a blister. Citramon-Darnitsa should also not be consumed by children under adolescence, due to the presence of acetylsalicylic acid. In its composition: acetylsalicylic acid, paracetamol, starch, cocoa, other auxiliary components.

Citramon-Darnitsa contains caffeine, but in smaller proportions compared to other drugs.

Citramon forte

Release form: tablets. Ingredients: citric acid, starch, acetylsalicylic acid, paracetamol, caffeine, etc. Dosage: one to two tablets 2-3 per day. It is recommended to take the medicine only for adults and children over 14 years of age.

Indications for use

What helps Citramon? The medicine is used to overcome pain before menstruation, toothache, headaches of various origins.

What do citramone granules help with? The medicine relieves febrile conditions with influenza and colds, eliminates pain with neuralgia, myalgia.

The use of medicine for children

Citramon is contraindicated in children under 14 years of age. Acetylsalicylic acid, which is part of the product, negatively affects the mucous membrane of the stomach and intestines.

Use of medicine for pregnant women

The drug should not be used by pregnant women who are in the 1st trimester and 3rd trimester of pregnancy. This can lead to congenital pathology of the fetus and lead to abnormalities in its development. In addition, acetylsalicylic acid increases the risk of bleeding during childbirth.

Even if a pregnant woman decides to take Citramon in the 2nd trimester of pregnancy, she will definitely need to consult a doctor

Application during breastfeeding

It is not recommended to take the medicine of a nursing mother during this period. Reasons to refuse the drug:

  • At this time, citramon can adversely affect the gastrointestinal tract, causing gastritis or an ulcer.
  • Caffeine stimulates the nervous system, and together with milk, this substance enters the body of a newborn. Negative symptoms of caffeine intake include insomnia, irritability, vomiting, and nausea.
  • In addition, paracetamol, contained in many forms of citramone, has a negative effect on the liver. The child's body is unable to cope with it and the drug will have a toxic effect on the child's liver.
  • Acetylsalicylic acid badly impairs blood clotting, and when feeding it is easy to harm not only yourself, but also your baby.

Contraindications

  • Allergic reactions to drug components
  • Blood clotting problems (hemophilia)
  • Severe form of arterial hypertension
  • Stomach ulcer and gastritis
  • Acute liver or kidney failure
  • Atherosclerosis
  • Ischemic disease
  • Age of the patient (does not apply to children)
  • Upcoming surgery

drug and alcohol

Citramon categorically cannot be combined with the use of alcoholic beverages. This leads to bleeding, stomach ulcers, erosions. The consequences are neurological abnormalities: tinnitus occurs, partial hearing loss is possible, anxiety, hallucinations, and convulsions often occur. Taking citramon with alcohol in exceptional cases causes loss of consciousness, nausea, anaphylactic shock.

Citramon has a toxic effect on the liver.

Instructions for use, dosage

How to take Citramon? Tablets are drunk during a meal or after a meal. Recommended dosage: one tablet no more than once every four hours. If the pain is severe, then the dosage is adjusted: the patient can drink 2 tablets. Daily dosage: about 4 tablets per 24 hours.

Instructions for use of Citramon says that the medicine can be drunk no more than 8 tablets per day. The duration of the course of taking the medicine is not more than 10 days.

Taking Citramon tablets, according to the instructions for use, is enough for 5 days to remove acute pain, and in order to reduce fever: 2-3 days.

Changes in dosage and duration of the course must be agreed with the attending physician.

Overdose

If the dose of the drug is exceeded, then the patient experiences attacks of nausea and vomiting, pain in the stomach. The patient complains of tinnitus; his reactions are inhibited; breathe heavily; urine is difficult to excrete. In particularly difficult cases, convulsions begin, the patient loses consciousness.

An overdose of citramon does not endanger a person's life, but in the long term, a long-term overdose threatens with a stomach ulcer, anemia, arrhythmia, tachycardia, kidney and liver problems.

In case of an overdose of the medicine, you should rinse the stomach and see a doctor.

Side effects

The use of the medicine can cause allergies, stomach pain, nausea. The patient's blood pressure rises, toxic damage to the liver and kidneys begins, blood clotting is disturbed.

Often, patients report difficulty in excreting urine from the body and exacerbation of gout.

Interaction with other drugs

If you take the medicine with heparin, barbiturates, epilepsy drugs and a number of other drugs, then it is possible that the toxic effect on the liver and kidneys will increase. Before taking other medicines, the patient should consult a doctor.

special instructions

The drug is not used in renal and hepatic insufficiency. For other diseases of the liver and kidneys, a doctor's consultation is necessary.

The cost of drugs under the brand name "Citramon" varies depending on the markup of the pharmacy chain, the patient's region of residence and the purchase price from the supplier.

On average, Citramon-Borimed can be bought for 2-5 rubles, Citramon P will be a little more expensive and costs from 8 to 15 rubles. Citramon-Lekt at average pharmacy prices will be 18–25 rubles, Citramon-MFF will be slightly cheaper from 15 to 18 rubles. And Citramon-Ultra (in the shell) is sold at a price of 45-50 rubles.

Storage and dispensing from the pharmacy

The medicine is kept out of the reach of children. It is desirable that the storage place is cool. Shelf life from 36 to 60 months from the date of manufacture.

Analogues

Despite its popularity, there are not so many drugs similar to citramone. Almost all of them contain acetylsalicylic acid.

  • Askofen. The composition is similar to Citramon, enriched vaseline oil, talc, etc. Used to treat headaches, fevers, lumbago, radicular syndrome. The price is about 25 rubles.
  • Acepar. The composition does not differ from citramone. Available in granules for suspension, capsules and tablets. Price: 30–35 rubles.
  • migrenol. Ingredients: caffeine and paracetamol, auxiliary components. Available in the form of coated tablets. The average cost is from 160 rubles.

Reviews

Patients characterize citramon as an effective pain reliever with an affordable cost, marking it among many drugs of a similar profile. Most people consider it a good drug, which has proven its effectiveness for many years, which is easy to buy at any pharmacy.

Does citramon thin the blood?

Yes, the drug contains components that thin the blood, which makes it inappropriate for patients who have a tendency to bleed.

If a person is preparing for an operation, then taking Citramon is also not worth it.

An allergic reaction to a medication can occur even when taking one pill. The most common allergen is aspirin in its composition.

Symptoms of an allergic reaction:

Much less often, patients are allergic to paracetamol or caffeine, which are part of citramon.

FAQ

Use during menstruation

This medicine is effective for the relief of pain before and during menstruation. In addition, it helps with vegetovascular dystonia, the manifestations of which often occur during this period. Caffeine in the composition of the tablets relieves depression, eliminates headaches and increases blood pressure.

Citramon helps relieve discomfort in the mammary glands, removing excess fluid from the tissues. Eliminates headaches, helps to defeat weakness and lethargy, improving performance, increasing the endurance of the body.

What is better citramon or askofen?

Both drugs have a similar composition and effect. Their difference is in the proportion of active substances. Askofene contains more caffeine and paracetamol, but less acetylsalicylic acid. Askofen can be used as a substitute. Both drugs are equally effective, but for patients with blood clotting problems, it is better to use askofen.

Both drugs have a similar spectrum of action, but at the same time they have different composition. The mechanism of action of analgin on the source of pain is different from the action of citramone.

Analgin, thanks to sodium metamizole, does not allow pain impulses to pass to the brain, relieves the excitability of the patient's pain centers. It has less effect on the gastrointestinal tract than citramon, has an antipyretic effect. It lowers the temperature better than aspirin, paracetamol and ibuprofen. It is an antispasmodic.

Analgin has a stronger effect in comparison with citramon, in those moments when you need to relieve spasm or reduce the temperature during fever. But it is banned in many countries because of the risk of agranulocytosis, which sometimes leads to death.

In some cases, analgin is more effective than citramon, but more dangerous for the human body.

Are Citramon and Paracetamol the same thing?

No. Paracetamol is an antipyretic drug. It is one of the active elements of Citramon, along with caffeine and acetylsalicylic acid.

Can I drink with a cold?

Citramon does not cure colds, but it can extinguish a number of cold symptoms, including muscle pain, eliminate headaches, relieve feelings of fatigue and drowsiness.

Citramon reduces the temperature, relieves febrile conditions with flu and colds, thanks to paracetamol in the composition.

Citramon is an effective remedy with an affordable cost for any patient. It perfectly relieves pain of low and medium intensity of various genesis, helps women to relieve premenstrual syndrome. At the same time, like any drug, it has a number of side effects (allergies, complications with the liver and kidneys, a negative effect on gastrointestinal tract). Its big disadvantage will be the impossibility of application for pediatrics. Like any medicine, it is best to use it after consulting a doctor.

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Read the opinion of doctors on this issue

Having listened to the advice of friends and acquaintances, we thoughtlessly take medicines, considering them harmless and rather weak.

However, the composition of any drug includes substances that affect our body in different ways. Therefore, before taking a medicine, it is still better to learn more about its effect on the body, especially if it is taken regularly.

Citramon is a popular pain reliever that people can use without any control, without thinking about how it affects the body. There is even a myth that this medicine helps get rid of a hangover. Knowing the composition of this drug will help to understand the meaning of its action.

It cannot be said that citramone has so many contraindications. However, there are quite serious ones: it should not be taken during pregnancy; after childbirth, if the woman is breastfeeding; before operations; with gout and diseased liver.

Most of the drugs currently marketed under the name "Citramon", "Aquacitramon" and "Citramon-P" include only aspirin (acetylsalicylic acid), caffeine and paracetamol. Modern Citramon no longer contains phenacetin, as it is recognized as a toxic substance.

This drug is most helpful for headaches. different origin, and also slightly reduces toothache and muscle pain. It is also used as an antipyretic and anti-inflammatory agent. The composition of the substances in citramone is selected so that they enhance and complement each other's action, so the effect of taking the medicine comes quite quickly:

Aspirin relieves inflammation, lowers body temperature and reduces pain in body tissues;

Caffeine has an invigorating effect and enhances overall blood circulation;

Paracetamol neutralizes the substances that cause headaches.

As for taking citramone with a hangover, this is just a myth. main reason A hangover is a violation of the water-salt balance, which the drug cannot fix. It undoubtedly has a short-term effect, but it can bring great harm, because paracetamol will heavily load the liver, and together with decay products, it can lead to an increase in hangover. In addition, caffeine will increase tissue oxygen demand, which can increase nausea and even induce vomiting. Aspirin can harm the gastrointestinal tract.

As you can see, it is also necessary to study well-known medicines so as not to accidentally harm your body.

The drug Citramon has been known for several decades as a universal pain reliever. Previously, its active ingredients were: phenacetin, aspirin, caffeine. Today, the traditional version is not produced, and the composition of the drug has changed somewhat - instead of phenacetin, paracetamol is added to it.

Citramon is most effective for headaches, but, thanks to the improvement of the drug, it is also prescribed to relieve inflammation in muscles, joints and bones, from algomenorrhea, febrile syndrome.

Does Citramon help with headaches?

described pharmacological drug able to stop pain syndrome, but only mild to moderate. Intense attacks of pulsating, squeezing, stabbing and other pain Citramon will not be able to eliminate.

An analgesic is sometimes prescribed to treat migraines. It is worth noting that in this case Citramon helps only at the very beginning of the development of pain or at the first signs of an aura. These pills do not stop an acute migraine attack.

How does Citramon work for headaches?

The drug is based on 3 active ingredients:

  1. Aspirin or acetylsalicylic acid. The compound produces an antipyretic effect, and also stops the pain syndrome provoked by the inflammatory process. Additionally, aspirin improves blood microcirculation and prevents the formation of blood clots in the vessels.
  2. Paracetamol. The ingredient directly affects the body's thermoregulatory centers in the hypothalamus, reduces the production of prostaglandins. Due to this, a pronounced analgesic and antipyretic effect is achieved.
  3. Caffeine. In a small dosage, this component normalizes blood flow and increases the tone of cerebral vessels, thereby enhancing the effect of the use of the 2 compounds described above.

The action of Citramon in headache is due to the combination of the considered ingredients. Taking the pill allows you to simultaneously stop inflammatory processes, pain syndrome, improve blood supply to brain tissues and oxygen supply to them, reduce blood viscosity and platelet count, increase efficiency, mental and physical activity.

Is it possible to drink Citramon with headaches and high blood pressure?

Given the content of caffeine in the presented medication, patients with arterial hypertension are afraid to take it because of the risk of an even greater increase in pressure. However, the concentration of this component is extremely low (30 mg), which does not allow it to have a stimulating effect on the central nervous system. Accordingly, Citramon is allowed to be used even by hypertensive patients at the time of an increase in blood pressure.

The only exception is portal hypertension. With this diagnosis, the combined anesthetic drug is contraindicated.

Is Citramon harmful with frequent use for headaches?

Like any other analgesic, Citramon is undesirable to take. long time or abuse it. Otherwise, a number of negative side effects, often irreversible, often occur. Among them, the following pathologies are most common:

  • hypocoagulation;
  • chronic headache;
  • constant tinnitus;
  • nosebleeds;
  • visual impairment;
  • kidney damage;
  • metabolic acidosis;
  • frequent and severe dizziness;
  • bleeding gums;
  • papillary necrosis;
  • hyperpyrexia;
  • decreased aggregation and functionality of platelets;
  • purpura and other hemorrhagic syndromes;
  • deterioration of liver function;
  • regular vomiting;
  • deafness;
  • disorders of the psyche and the central nervous system;
  • Reye's syndrome.

Citramon benefit and harm

Tell me, when was the last time you went to the pharmacy and bought Citramon, did you take along with the purchase the instructions for it? Once upon a time? And when did you read it? How much did you understand from this?

Do you know that Citromon DO NOT take:

Children under 15

For gastritis or ulcers

With severe arterial hypertension (high blood pressure)

After drinking alcohol

For insomnia (sleep disorders)

Caution in liver disease

And how do you like folk thoughts about citramone: your head hurts - take citramone - it will help anyone - and if it doesn’t help, it won’t hurt; menstruation interferes with living with pain - citramone, citramone is the safest medicine, take citramone for a cold, and so on, yesterday you had a good rest - it will help again, drinking citramone often is not dangerous, it helps from everything, if a child - then half a tablet, a cat - a quarter. Sounds like what you think of citramone? If not you, then your acquaintances, friends, parents. I'm just scared of people who come to the pharmacy and take popachek right away - this means that they drink it all the time. It is especially a pity for pregnant women, who only by the end of the term find out that citramon is contraindicated for pregnant women.

Let's figure out what citramon is, is it useful or harmful.

So, the truth about Citramon

1) What is included in the composition of citramon

Citramon contains aspirin, paracetamol and caffeine. Different manufacturers call this drug differently and slightly vary the amount of active ingredients:

2) What are the indications for taking Citramon:

Pain syndrome of mild and moderate severity (of various origins):

  • headache;
  • migraine;
  • toothache;
  • neuralgia;
  • myalgia;
  • arthralgia;
  • algomenorrhea.
  • febrile syndrome with acute respiratory infections and influenza
  • 3) To whom citramon is contraindicated:

    These are various allergic reactions to any substance that is part of citramone, including not only active, but also auxiliary substances.

    For any gastritis-like pain, the drug is contraindicated, especially if you have gastritis or a stomach ulcer or intestinal ulcer in the acute (unhealed) phase. Even when using low doses of aspirin - mg / day (as an antiplatelet agent) - aspirin can cause damage to the gastric mucosa and lead to the development of erosions and / or ulcers, which are often complicated by bleeding. The risk of bleeding is dose-dependent: when administered at a dose of 75 mg / day, it is 40% lower than at a dose of 300 mg, and 30% lower than at a dose of 150 mg. Even slightly, but constantly bleeding erosions and ulcers can lead to a systematic loss of blood in the feces (2-5 ml / day) and the development of iron deficiency anemia.

    The first sign is a change in the color of feces to dark

    Characteristic for some asthmatics: a variant of endogenous or mixed bronchial asthma, in which one of the factors contributing to the narrowing of the bronchi are non-steroidal anti-inflammatory drugs (NSAIDs), including acetylsalicylic acid; consists of a triad of symptoms: polyposis rhinosinusitis, asthma attacks and intolerance to NSAIDs

    Hereditary disease associated with impaired coagulation (the process of blood clotting); with this disease, hemorrhages occur in the joints, muscles and internal organs, both spontaneously and as a result of trauma or surgery. With hemophilia, the risk of a patient's death from hemorrhage increases sharply, even with a minor injury, since it is very difficult to stop it (weak blood clotting).

    Hemorrhagic diathesis includes diseases based on violations of the vascular wall and various parts of the hemostasis system, causing increased bleeding or a tendency to its occurrence. On the globe, about 5 million people suffer from primary hemorrhagic manifestations. Given that secondary hemorrhages, such as DIC in the pre-agonal state, are not always fixed, one can imagine the prevalence of hemorrhagic diathesis.

    Deficiency of the clotting factor prothrombin in the blood, as a result of which a person has an increased tendency to bleed. Hypoprothrombinemia may be hereditary or may develop as a result of any liver disease, vitamin K deficiency in the body, or the use of anticoagulants in the treatment of another disease.

    This is a syndrome of increased pressure in the portal vein system caused by impaired blood flow in the portal vessels, hepatic veins and inferior vena cava. In most cases, portal hypertension is a consequence of cirrhosis of the liver, schistosomiasis (in endemic areas), structural abnormalities of the hepatic vessels.

    Vitamin K deficiency may develop due to intestinal malabsorption (such as bile duct obstruction), therapeutic or accidental absorption of vitamin K antagonists, or, very rarely, dietary vitamin K deficiency. As a result of acquired vitamin K deficiency, Gla-radicals are not completely formed, as a result of which Gla-proteins do not fully perform their functions. The above factors can lead to the following: profuse internal hemorrhages, cartilage ossification, severe deformation of developing bones, or salt deposits on the walls of arterial vessels.

    With prolonged use of paracetamol more than 1 tablet per day (1000 or more tablets per life), the risk of developing severe analgesic nephropathy, leading to terminal renal failure, doubles. It is based on the nephrotoxic effect of paracetamol metabolites, especially para-aminophenol, which accumulates in the renal papillae, binds to SH-groups, causing severe violations of the function and structure of cells, up to their death. At the same time, the systematic use of aspirin is not associated with such a risk. Thus, paracetamol is more nephrotoxic than aspirin and should not be considered a "perfectly safe" drug.

    Citramon is contraindicated in the 1st and 3rd trimesters of pregnancy due to its constituent acetylsalicylic acid. And caffeine, which is part of citramon, enhances the effect of acetylsalicylic acid. Acetylsalicylic acid or aspirin has a teratogenic effect on the fetus; with prolonged use in the first trimester, it can lead to a malformation - splitting of the upper palate; in the III trimester - to inhibition of labor activity, to the closure of the arterial duct in the fetus, which causes hyperplasia of the pulmonary vessels and hypertension in the vessels of the pulmonary circulation. Citramon causes increased bleeding due to impaired platelet aggregation and inhibition of prothrombin synthesis in the liver, which during childbirth is dangerous with severe bleeding.

    Acetylsalicylic acid, which is part of Citramon, is excreted in breast milk, which increases the risk of bleeding in a child due to impaired platelet function, can also lead to Reye's Syndrome, therefore, maternal acetylsalicylic acid should not be used during lactation.

    Paracetamol is excreted in breast milk: the content in milk is 0.04-0.23% of the dose taken by the mother, paracetamol is contraindicated in the neonatal period.

    Patients develop hereditary nonspherocytic hemolytic anemia of varying severity.

    The incidence of arterial hypertension in Russia among men is 39.2%, among women - 41.1%. However, 58% of women and 37.1% of men are informed about their illness, drug treatment is carried out in 45.7 and 21.6% of cases, respectively. The therapy is effective only in 17.5% of women and 5.7% of men.

    The incidence of arterial hypertension increases as the age of patients increases. In Russia, approximately 80% of people over the age of 65 are diagnosed with elevated blood pressure levels. In the world, this figure reaches 60%. Approximately 65 million people in the United States suffer from arterial hypertension. At the same time, only 79% are aware of their illness. Courses of treatment are 59% of patients.

    Ischemic heart disease (CHD) is a pathological condition characterized by absolute or relative impairment of myocardial blood supply due to damage to the coronary arteries of the heart. Coronary artery disease is a myocardial disorder caused by a disorder of the coronary circulation resulting from an imbalance between the coronary blood flow and the metabolic needs of the heart muscle. In other words, the myocardium needs more oxygen than it receives from the blood. IHD can occur acutely (in the form of myocardial infarction), as well as chronically (periodic attacks of angina pectoris)

    The incidence of glaucoma in adults is 1-1.5 cases per 100 people.

    Caffeine, which is part of citramone, increases nervous excitability

    Insomnia often occurs in older people, caffeine, which is part of citramone, aggravates insomnia

  • surgical interventions accompanied by bleeding
  • Before surgery, to reduce bleeding during surgery and in the postoperative period, salicylates should be discontinued 5-7 days in advance.

    Up to 15 years - the risk of developing Reye's syndrome in children with hyperthermia on the background of viral diseases.

    Reye's syndrome - develops when aspirin (part of citramon) is prescribed to children with viral infections (flu, chicken pox). It presents with severe encephalopathy, cerebral edema, and liver damage that occurs without jaundice, but with high levels of cholesterol and liver enzymes. Gives very high lethality (up to 80%). Therefore, aspirin should not be used for acute respiratory viral infections in children of the first 12 years of life.

    Overdose or poisoning in mild cases is manifested by symptoms of "salicylicism": tinnitus (a sign of "saturation" with salicylate), deafness, hearing loss, headache, visual disturbances, sometimes nausea and vomiting. In severe intoxication, disorders of the central nervous system and water-electrolyte metabolism develop. There is shortness of breath (as a result of stimulation of the respiratory center), acid-base disorders (first respiratory alkalosis due to loss of carbon dioxide, then metabolic acidosis due to inhibition of tissue metabolism), polyuria, hyperthermia, dehydration. Myocardial oxygen consumption increases, heart failure, pulmonary edema may develop. The most sensitive to the toxic effect of salicylate are children under 5 years of age, in whom, as in adults, it is manifested by severe disorders of the acid-base state and neurological symptoms. The severity of intoxication depends on the dose of aspirin taken (Table 6).

    Mild to moderate intoxication occurs at mg/kg, severe poisoning occurs at mg/kg, and doses greater than 500 mg/kg are potentially lethal. come back

    4) Who needs to take Citramon with caution:

    Acetylsalicylic acid, even in small doses, reduces the excretion of uric acid from the body, which can cause an acute attack of gout in predisposed patients.

    Paracetamol is hepatotoxic when taken in very high doses. Its simultaneous administration at a dose of more than 10 g in adults or more than 140 mg / kg in children leads to poisoning, accompanied by severe liver damage. The reason is the depletion of glutathione reserves and the accumulation of intermediate products of the metabolism of paracetamol, which have a hepatotoxic effect. In recent years, data have appeared on the hepatotoxic effect of paracetamol with its moderate overdose, with the appointment of paracetamol in high therapeutic doses and the simultaneous use of inducers of the microsomal enzyme system of the liver P-450 (antihistamines, glucocorticoids, phenobarbital, ethacrynic acid), as well as in alcoholics.

    Even when taken in therapeutic doses (1.5 g / day, according to GF X), paracetamol can cause serious liver damage in alcoholics, as well as in persons who systematically drink alcohol (for men - a daily intake of more than 700 ml of beer or 200 ml of wine, for women - doses are 2 times less), especially if paracetamol was taken after a short period of time after drinking alcohol. With the simultaneous use of aspirin with ethanol (alcohol), the effect of acetylsalicylic acid on the gastrointestinal tract may be enhanced.

    Think about how often, how many times a week do you while away the evening with a bottle of beer? And so - taking citramone as a remedy for a hangover is very harmful to your liver. In various kinds of advice on the Internet, how to get rid of a morning hangover, advice such as take a citramone tablet + a paracetamol tablet is far from the last place. And many practice to drink coldrex maxigripp or teraflu extra (the maximum possible content of paracetamol) from a hangover. Helps, I do not argue - but at what cost?

    With prolonged use of paracetamol more than 1 tablet per day (1000 or more tablets per life), the risk of developing severe analgesic nephropathy, leading to terminal renal failure, doubles.

    Caffeine, like other CNS stimulants, is contraindicated in hyperexcitability, insomnia, severe hypertension and atherosclerosis, in organic diseases of the cardiovascular system, in old age, and in glaucoma.

    Conclusions:

    I do not protest against taking citramone for pain - this is a good remedy. But you need to use it with an eye on contraindications and make sure that it does not become a habit, that citramone does not become a panacea for all types of misfortunes. And please - do not give Citramon to children and pregnant women!

    Question:

    Good afternoon Please tell me, is it possible to drink Citramon from a headache at an early stage of pregnancy? And if not, what is still possible?

    And one more question: I drank the antibiotic Augmentin in the first or second week of pregnancy (I didn’t know that I was pregnant). The contraindications say that pregnant women should not. Tell me, how dangerous is this in my case? Can this really harm the baby? This issue is very worrisome. Thank you in advance.

    Answer:

    Citramon is contraindicated in the 1st and 3rd trimesters of pregnancy due to its constituent acetylsalicylic acid. And caffeine, which is part of citramon, enhances the effect of acetylsalicylic acid. Acetylsalicylic acid or aspirin has a teratogenic effect on the fetus; with prolonged use in the first trimester, it can lead to a malformation - splitting of the upper palate; in the III trimester - to inhibition of labor activity, to the closure of the arterial duct in the fetus, which causes hyperplasia of the pulmonary vessels and hypertension in the vessels of the pulmonary circulation. Thus, taking Citramon during pregnancy is contraindicated. If you have frequent headaches during pregnancy, you need to find out their cause. Paracetamol can be used for migraine headaches, as well as tension headaches (with the permission of your doctor). From painkillers, you can also take No-shpu.

    Augmentin during pregnancy is taken with caution and under the supervision of your doctor. Amoxicillin, which is part of Augmentin, does not have a teratogenic effect. In several studies that I found mention of, there was no adverse effect of amoxicillin / clavulanate (Augmentin) on the fetus when using the drug in pregnant women in the first trimester.

    The next time you visit your doctor who is managing your pregnancy, be sure to tell him about the medicines you are taking in the early stages. He will prescribe additional studies that will help eliminate the possibility of malformations.

    Question:

    Unfortunately, paracetamol and no-shpa do not help at all with my frequent severe headaches (ultrasound of the vessels of the head, tomography, and other studies did not reveal the cause of the migraine). I have been married for four years, but I am afraid of getting pregnant precisely because of a migraine. The first pregnancy was unsuccessful (at the 6th week there was a miscarriage after taking two tablets of Citramon). Help, please, in my case.

    Answer:

    I can't recommend anything new. Of the analgesics for migraine during pregnancy, only paracetamol (acetaminophen) can be used in small doses in the 1st and 2nd trimesters. In the 3rd trimester, it is contraindicated. Other analgesics are contraindicated. If paracetamol does not help you, try combining it with caffeine (how to take it is described below). Citramon should not be taken during pregnancy. The component of citramon that could cause a miscarriage is acetylsalicylic acid. It is contraindicated in the 1st and 3rd trimester.

    It is necessary to identify patterns in the appearance of migraine - perhaps this is a reaction to the following factors: stress, nervous and physical overexertion, nutritional factors (cheese, chocolate, nuts, fish), alcohol (most often beer and red wine, champagne), hormonal causes (menstrual cycle, taking contraceptives), sleep (lack or excess), weather factors (change of weather, change of climatic conditions). Try to avoid these factors.

    With migraine, intestinal motility slows down and is often accompanied by nausea, sometimes vomiting. With nausea and vomiting that accompanies an attack, you can take cerucal (metoclopramide) - but it is contraindicated in the 1st trimester of pregnancy. Due to the slowing down of the intestines, it is recommended to take migraine medications in combination with caffeine, which facilitates the absorption of drugs and accelerates their action. Caffeine sodium benzoate for normal patients is prescribed 200 mg during an attack of pain, then 100 mg 2-3 times a day for several days. I have not found any serious contraindications for pregnant women. But the dose definitely needs to be reduced. Consult with your doctor. Sometimes papazol also helps. It is not contraindicated in pregnant women.

    Question:

    Hello! I was in the clinic, I had a miscarriage, doctors allowed all pregnant women to have citramone for headaches, I thought it was harmless, I’m now 4 weeks pregnant, I drank 10 pills during these 4 weeks, of course not every day, how serious is it?

    Answer:

    The instructions for the drug Citramon clearly state that it is contraindicated in the first and third trimester of pregnancy, as well as during breastfeeding. Acetylsalicylic acid, which is part of citramon, has a teratogenic effect, so taking the drug in the first trimester of pregnancy is strictly prohibited in order to avoid the occurrence of congenital anomalies in the development of the fetus. Why some doctors allow him to take it is not clear to me. When planning conception and pregnancy, before taking any drug, be sure to read the instructions (contraindications) even for the simplest and most well-known drugs in your opinion. Because otherwise you can take something harmful to the unborn baby. Try to take less medicines, even those allowed according to the instructions. How serious it is for your unborn child to take citramone in the first trimester can only be found out by your doctor who leads the pregnancy. Tell him as soon as possible about the fact of taking Citramon.