How to prepare a 0.25 percent solution. Formula for solving problems for diluting solutions. Solution with Dimexide and Novocaine for pain relief

In the process of preparing solutions by diluting concentrates, quick and error-free calculations of the required amount of the initial concentrate and solvent combined into one solution should be carried out.

When calculating the dilution of concentrates, in which the concentration is indicated as the ratio of the amount of solute to the amount of solution, the required amount of dry matter is multiplied by the dilution value, i.e. to the second digit of the concentration ratio.

For example, if the required amount of dry soluble substance is 5 g, and the concentrated solution has a concentration of 1: 10, then the required amount of concentrate solution will be: 5 x 10 = 50 (ml).

If the concentration of the blank solution is indicated as the ratio of the solute to the solvent reduced to unity (for example, 1 + 3), then, by analogy with the previous case of a concentrated solution, it is necessary to take:

5 x (1 + 3) = 20 (ml).

If the concentration of the semi-finished solution is expressed as a percentage and is equal, for example, to 10%, then under the same conditions it must be taken: 5 x 100/10 = 50 (ml).

In pharmacy practice, it is very often necessary to determine the required amount of a stock solution by its concentration (in percent), the amount of solution to be prepared and its concentration (in percent), the amount of diluted solution to be prepared and its concentration (also in percent).

For example, there is an X% concentrated solution.

To determine the amount of this solution required to obtain A ml of a diluted solution with a concentration of Y% (let's denote it B), it is necessary to carry out the following calculations.

The amount of a dissolved substance in a concentrated solution is: X x B / 100, and in the resulting diluted solution - Y x A / 100. Since both values ​​\u200b\u200bare equal, then, respectively:

X x B / 100 = Y x A / 100.

From here we express the volume of X% concentrated solution required to obtain A ml of Y% diluted solution:

B \u003d Y x A / X (ml). And the amount of solvent necessary to dilute the workpiece, therefore, will be equal to A - B (ml).

Sometimes it is necessary to prepare solutions of a given concentration from two solutions (one with a higher and the other with a lower concentration). For example, there are two solutions with concentrations X and Y%. In order to determine in what ratio these solutions should be mixed in order to get C ml of a solution with a concentration of Z%, we carry out calculations. Denote the required amount X-percent solution through D, then a Y-% solution will require (C - D) ml. Considering the previous calculations, we get:

X x D + Y x (C - D) = Z x C.

Hence: D \u003d C x (Z - Y) / (X - Y) (ml).

Very convenient for diluting concentrated solutions is the use of the so-called mixing rule. Let's assume that from two solutions with concentrations X and Y% it is necessary to prepare a Z% solution. Determine in what ratio you need to mix the initial solutions. Let the desired values ​​be equal: A (X% solution) and B (Y% solution) ml.

Therefore, the amount of the prepared Z% solution should be equal to: (A + B) ml.

Then: X x A + Y x B \u003d Z x (A + B), or A / B \u003d (Z - Y) / (X - Z).

Equating the corresponding members of the relations, we have:

A \u003d Z - Y, B \u003d X - Z.

Example 1

Let us calculate in what proportions it is necessary to mix 35% and 15% solutions in order to obtain a 20% solution.

After completing the necessary calculations, we get that you need to mix 5 parts of a 35% solution and 15 parts of a 15% solution. As a result of mixing, 20 parts of a 20% solution will be obtained.

Example 2

Let us calculate in what proportions it is necessary to mix water, i.e. 0% solution, and 25% solution to get 10% solution. After the calculations, we get that you need to mix 10 parts of a 25% solution and 15 parts of water. As a result, 25 parts of a 10% solution will be obtained.

Determine what you know and what you don't. In chemistry, dilution usually means obtaining a small amount of a solution of known concentration, then diluting it with a neutral liquid (eg water) and thus obtaining a less concentrated solution of a larger volume. This operation is very often used in chemical laboratories, therefore, reagents are stored in them in a concentrated form for convenience and diluted if necessary. In practice, it is usually known initial concentration, as well as the concentration and volume of the solution to be obtained; wherein the volume of the concentrated solution to be diluted is unknown.

  • Substitute known values into the formula C 1 V 1 \u003d C 2 V 2. In this formula, C 1 is the concentration of the initial solution, V 1 is its volume, C 2 is the concentration of the final solution, and V 2 is its volume. From the resulting equation, you can easily determine the desired value.

    • Sometimes it is useful to put a question mark in front of the value you want to find.
    • Let's go back to our example. Substitute the known values ​​into the equation:
      • C 1 V 1 = C 2 V 2
      • (5 M)V 1 = (1 mM) (1 L). Concentrations have different units of measure. Let's dwell on this in a little more detail.
  • Take into account any difference in units of measure. Since dilution leads to a decrease in concentration, and often a significant one, concentrations are sometimes measured in different units. If you miss this, you can make a mistake with the result by several orders of magnitude. Convert all concentration and volume values ​​to the same units before solving the equation.

    • In our case, two concentration units are used, M and mM. Let's convert everything to M:
      • 1 mM × 1 M/1.000 mM
      • = 0.001M.
  • Let's solve the equation. When you have reduced all the quantities to the same units of measure, you can solve the equation. To solve it, knowledge of simple algebraic operations is almost always sufficient.

    • For our example: (5 M)V 1 = (1 mM) (1 L). Bringing everything to the same units, we solve the equation for V 1 .
      • (5 M)V 1 = (0.001 M) (1 L)
      • V 1 \u003d (0.001 M) (1 l) / (5 M).
      • V 1 = 0.0002 l, or 0.2 ml.
  • Think about applying the result in practice. Suppose you have calculated the required value, but still find it difficult to prepare a real solution. This situation is quite understandable - the language of mathematics and pure science is sometimes far from the real world. If you already know all four quantities in the equation C 1 V 1 \u003d C 2 V 2, proceed as follows:

    • Measure the volume V 1 of the solution with concentration C 1 . Then, add dilution liquid (water, etc.) to make the solution volume equal to V 2 . This new solution will have the required concentration (C 2).
    • In our example, we first measure 0.2 ml of the initial solution with a concentration of 5 M. Then we dilute it with water to a volume of 1 l: 1 l - 0.0002 l = 0.9998 l, that is, we add 999.8 ml of water to it. The resulting solution will have the required concentration of 1 mM.
  • It has a local antiseptic and analgesic effect, relieves inflammation. Dimexide easily passes through skin barriers and tends to carry other therapeutic components along with it, increasing their effectiveness.

  • with erysipelas of the skin - a solution of 50%;
  • pustular lesions, trophic ulcers - 30-40%;
  • eczema and streptoderma - concentration from 30 to 90%;
  • on burn surfaces - 20-30% solution.

    Do not take a compress with a solution of dimexide as a harmless remedy. The medicine is very strong, so you need to strictly observe the dosage (based on the nature of the disease) and the time of exposure. The concentrated solution causes burns. There are also serious contraindications. Dimexide can not be used for functional disorders of the kidneys and liver, cataracts, glaucoma, children under 12 years of age, during pregnancy. Do not forget about its ability to enhance the effect of other drugs, both medicinal and toxic. Therefore, care should be taken and compatibility with other medicinal substances should be taken into account.

    Throat compress

    Compress for bronchitis

    Compress on the joints

    A good therapeutic effect is given by compresses that have a complex composition. For example:

  • dimexide concentrate -50 ml;
  • water - 30 ml;
  • novocaine solution 2% - 30 ml;
  • hydrocortisone solution - 1 ampoule.

    Dimexide: instructions, medicinal properties, cost

    Dimexide is, without exaggeration, a unique drug, since it has not only antiseptic capabilities, but is also able to penetrate through the mucous membrane, skin reaching even deeply located inflammatory foci. At the very beginning of my medical practice, there were two clinical cases that convincingly proved the effectiveness of Dimexide.

    One of my patients had surgical removal wisdom tooth. A few days before, suppuration of the mucosa in this area had developed. After the operation, oral antibiotics and rinsing with antiseptics were prescribed, which usually give a noticeable effect after about 6-7 days. At the same time, the doctor recommended external compresses with Dimexide on the angle area mandible. Practically on the 4th day, the separation of pus from the wound stopped, healing was much faster. It is characteristic that the patient, about 5 minutes after applying the compress, clearly felt the taste of the medicine in his mouth, which had penetrated into oral cavity through the skin of the cheek, muscles, internal mucosa.

    Another illustrative case is the treatment of a furuncle in the lumbar region measuring 3 by 5 centimeters. The patient made an appointment with a surgeon, who was appointed a day later. There were no signs of early spontaneous opening of the abscess. During the day, dressings with 30% Dimexide were made three times, Cifran in tablets was additionally used and the furuncle opened, the contents of the focus began to drain into the bandage. Further, lotions were made regularly, on the fourth day the hyperemia and swelling disappeared, the treatment was carried out without surgery. However, the patient nevertheless consulted with the surgeon, self-treatment for purulent inflammation is unacceptable.

    By blocking hydroxyl radicals, Dimexide normalizes metabolic reactions, potentiates the action of antibiotics, and has an antimicrobial, analgesic effect. Helps reduce swelling, resorption of hematomas.

    • Systemic atherosclerotic changes.
    • Lactation period, pregnancy.
    • Vascular pathology: stroke, myocardial infarction, manifestations of angina pectoris.
    • Individual intolerance.
    • Cataract, glaucoma.
    • Lack of activity of the kidneys, liver.
    • Therapy for manifestations of eczema.
    • Furunculosis.
    • Autoimmune diseases: erythema nodosum, Bechterew's disease, scleroderma, rheumatoid arthritis, arthrosis, SLE.
    • Fungal lesions of the feet.
    • Treatment of burns, wounds.
    • Rheumatologists use Dimexide for symptoms of osteochondrosis.

    It is better to breed in a porcelain mug, pre-rinse with boiling water. If you plan to treat open wounds, use sterile water, wipes. The initial concentration of Dimexide is 99%, a dessert or a tablespoon is suitable for dosing. Approximate dosages: 1 part concentrate plus 2 parts water - 33%; 1:1 - we get 50 percent; 1:5 - 20%.

    Apply a small amount of solution to the skin beforehand to exclude hypersensitivity, wait 5 minutes if there is no pruritus, redness - you can use the drug. Polyethylene is placed on top of the napkin, which protects the bandage from quick drying, then cotton fabric. Standard course - 2 weeks. With streptoderma, eczema - the percentage of the solution is 40-90; pain syndrome, suppurative processes - 30-50; face area - a solution with a concentration of 10-20 is applied; washing of wound surfaces - 3-5%.

    Stored in the package for 2 years. At room temperatures.

    Rarely, local irritation, symptoms of dermatitis, allergic reactions, dry skin, bronchospasm were noted.

    Released without a doctor's prescription. Estimated cost of medication:

    Goods for Health and Beauty, Sports and Leisure. Delivery across Russia.

    Website Neboleem-net.ru

    Copying materials is prohibited.

    Before using medicines, consult with your doctor. 18+

    Preparation and application of compresses with Dimexide

    The drug Dimexide is widely used by doctors of various specializations. Its main area of ​​application remains the treatment of joint diseases, however, some unique properties make it indispensable in other areas of medicine, such as dermatology and gynecology. The drug is not used in pure form. How to dilute Dimexide to prepare a solution for a compress, you will learn from the instructions for use below.

    Indications

    Dimexide (Dimethyl sulfoxide) is a concentrate, a clear, colorless liquid, intended for external topical use.

    Indicated for treatment:

    • inflammatory pathologies of the musculoskeletal system (osteoarthrosis, arthritis, myositis, radiculopathy, ankylosing spondylitis);
    • sprains, muscles;
    • bruises;
    • arthralgia;
    • wounds, abscesses;
    • traumatic infiltrates;
    • osteomyelitis;
    • streptoderma;
    • furunculosis;
    • acne
    • gynecological problems;
    • skin infections;
    • erythematous rash.

    pharmachologic effect

    The drug exhibits the following properties:

    1. Local anesthetic.
    2. Antimicrobial.
    3. Anti-inflammatory.
    4. Painkiller.
    5. Acts as a conductor.

    The latter action is based on the special properties of Dimexide, which allow it to penetrate deep into tissues, which has gained popularity in many areas of medicine.

    The drug is often added to ointments or cosmetic creams for better penetration. nutrients to the goal. The transport properties of the drug are used in folk recipes and medical lotions.

    Dimexide quickly penetrates deep into the tissues. After 5 minutes from the start of the procedure, the effect of the drug is already felt by the patient. Maximum concentration active substance fixed after 4 hours and can last up to 3 days.

    Application of the drug

    Dimexide is most often used in the form of compresses that contain a combination of medicinal substances.

    The compress is applied to areas of the skin that require treatment, slightly capturing neighboring healthy areas. It is recommended to change the compress up to 3 times a day. The compress is kept for at least 30 minutes, and the duration of the course of treatment is usually up to 20 procedures. However, all such nuances are corrected by the doctor.

    The effect of the drug depends on how the correct concentration of the drug you use:

    • Ulcers and erysipelas are treated with applications with a 50% solution.
    • With eczema and streptoderma, the concentration of the solution can reach 90%.
    • For purulent infections, a 40% concentration is used.
    • Local anesthesia is carried out with a solution of 25-50% concentration.
    • After surgical intervention, holding plastic surgery make applications with a 30% solution of Dimexide.
    • If necessary, make a compress on the face, Dimexide is used in a lower concentration, about 10%.

    Clicking, crunching various joints disturb adults, but it is especially disturbing when it clicks hip joint The child has.

    A sharp turn of the body, muscle spasm, severe pain. Who is unfamiliar with the symptoms of lumbago? About the method of treating the disease at home here: http://pomogispine.com/bolit-v/poyasnichno-kresttsovyj-otdel/lyumbago.html.

    How to dilute the compress solution

    To obtain the desired concentration of the solution, it is diluted with water (distilled or boiled) in the following proportions:

    • 50 ml of Dimexide + 30 ml of water + 30 ml of novocaine (2%) + hydrocortisone (1 ampoule).

    This composition has a good anti-inflammatory effect, relieves pain. In various recipes, the concentration of Dimexide may vary, while the amount of other components remains the same.

    How to make a compress

    The compress is applied as follows:

    1. Gauze pads of the right size are wetted in a solution of Dimexide in combination with other medicinal substances, if necessary. Do not use colored fabric instead of gauze, this significantly increases the risk of complications and allergies.
    2. A napkin is applied to the affected area, slightly capturing the healthy edge.
    3. From above, the napkin is covered with a plastic film to enhance the absorption of medicinal substances and minimize their evaporation to the outside.
    4. A linen or cotton fabric is applied over the film.

    Gynecological practice

    Dimexide is also widely used in the form of tampons. As a rule, this form is necessary for the treatment of gynecological problems, for example:

    A swab made of sterile cotton and soaked in a medicinal solution is inserted into the vagina. The solution may consist of a combination of drugs and Dimexide. In this case, the effect comes much faster.

    For use in the form of tampons, the concentrate is diluted in a ratio of 1: 9, that is, a 10% solution is made.

    The tampon should not be inserted deep. The effectiveness of such treatment is quite high, and all drugs will definitely get to the site of inflammation.

    Contraindications

    Dimexide is not used in people with the following diseases:

    1. Cardiovascular insufficiency.
    2. Angina.
    3. Atherosclerosis.
    4. Problems in the liver and kidneys.
    5. Glaucoma or cataract.

    Compresses with Dimexide are contraindicated in pregnant and lactating women, as well as people with hypersensitivity to dimethyl sulfoxide (active ingredient).

    Side effects

    The treatment is well tolerated by most patients. In rare cases, there may be complaints about:

    Pain, a bump under the knee, difficulty bending are the main signs of the formation of a Baker's cyst of the knee joint. What is the reason, how to treat pathology: http://pomogispine.com/bolit-v/konechnosti/kista-bejkera-kolennogo-sustava.html.

    How does Kuznetsov's applicator help with back and joint pain? Are needle mats, rollers, plates so harmless?

    Read about popular, inexpensive sanatoriums in the Moscow region, where people of retirement age can relax and improve their health, read here.

    Dimexide is extremely cheap and effective remedy. Its average price:

    • About 60 rubles per 100 ml in Russia.
    • About 15 UAH per 100 ml in Ukraine.

    Reviews

    Irina, 43 years old, Murmansk:

    “I have joint problems. Previously, they hurt only when walking or some kind of load, and in Lately aching pain worries even when I'm lying down. No ointments help, and you can take anti-inflammatory drugs orally for no longer than a week. Then the doctor advised me to make compresses with Dimexide.

    At first I ordered them in a special pharmacy that prepares medicines, and now I make them myself. I add various anti-inflammatory ointments to the diluted preparation. Help much better! If you are not lazy, do it constantly, then the effect persists for a long time. The main thing is that local treatment absolutely does not harm my health, but only helps. Dimexide is very effective, and for its price it is generally an ideal tool. ”

    Igor, 26 years old, Volgograd:

    "I am a sportsman. I have various injuries and sprains quite often. Immediately after this, you can’t go to training, but there’s no way to be treated for a long time. The doctor of our team said to do compresses with Dimexide, novocaine, adding any anti-inflammatory ointment. The pain goes away almost immediately, and after a few days the sprain heals. Now I use it all the time. Dimexide significantly improves the effect of any ointment, now I can buy the most expensive one and I will know that the money was well spent. ”

    Olga, 37 years old, Stavropol:

    “I bought Dimexide for my mother, and it was one of the few products that she agreed to use. She was skeptical about expensive ointments because of the price and said that they did not help her. Compresses with Dimexide proved to be effective both on their own and in combination with other means.

    Dimexide has been known for a long time, especially among older people who cannot afford expensive medicines. However, the effectiveness of this drug makes it worthy of widespread use.

    Dimexide shows one of the best quality / price ratios among the means for the treatment of joint diseases.

    There is only one reason - the spine.

    All materials on the site are for informational purposes only.

    Nmedicine.net

    The drug Dimexide is used very widely and not only in medical practice but also in cosmetology. With the help of Dimexide, they are successfully treated skin diseases, diseases of the musculoskeletal system, gynecological pathologies, etc. The medicine relieves pain and inflammation, destroys pathogenic bacteria.

    Usually Dimexide solution is used in a diluted form. How to properly dilute the Dimexide solution so as not to get burned - read about this on these pages.

    The main advantage of Dimexide is its rapid penetration through the skin and mucous membranes. In this case, the drug delivers deep into the tissues - to the focus of inflammation - dissolved in it medicinal substances. Dimexide is used externally as compresses or tampons. Before use, Dimexide should be diluted with water to obtain a solution of a certain concentration - in each specific case, its own.

    To prepare a solution of Dimexide, you need to use only two types of water - distilled and boiled.

    Before you start using Dimexide, you need to test yourself for the possibility allergic reaction for the drug. The test is done in the usual way: a few drops of 25% aqueous solution Dimxide and after half an hour there is a reaction on the skin. If there is no reaction, you can safely use the drug. If there are sensations of itching, redness, Dimexide should not be used.

    For the use of Dimexide as a treatment trophic ulcer you need to prepare a 30-50% solution. For the treatment of eczema (diffuse streptoderma), a more concentrated solution is used - 40-90%. For purulent skin lesions, a 30-40% solution is required, for superficial burns, a 20-30% solution of Dimexide is required. At erysipelas a 50% solution is used.

    The dilution procedure itself is as follows: you need to put on gloves, take a container, pour the required amount of Dimexidum concentrated agent into it and add distilled or boiled water. Make proportions based on a specific disease.

    • To obtain a 10% solution, 18 ml of water is taken, Dimexide - 2 ml.
    • To obtain a 20% solution: 8 ml of water and 2 ml of Dimexide.
    • To obtain a 25% solution: 6 ml of water and 2 ml of Dimexide.
    • To obtain a 30% solution: 14 ml of water and 6 ml of Dimexide.
    • To obtain a 40% solution: 6 ml of water and 4 ml of Dimexide.
    • To obtain a 50% solution: 5 ml of water and 5 ml of Dimexide.
    • To obtain a 90% solution: 2 ml of water and 18 ml of Dimexide.

    Instead of water, you can use vegetable oils especially for making tampons. A gauze bandage soaked in the prepared solution is applied to the diseased area, then a compress is made on top: a plastic wrap is applied and then a natural fabric (cotton, linen, wool). The compress is left for half an hour. Treatment continues for 10 days.

    Remember that you can not rub the Dimexide solution, massage your skin with it! This may cause chemical burn skin.

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    Compresses with dimexide.

    Compresses with dimexide: a stunning effect

    Dimexide is a concentrated, colorless, transparent solution with a specific odor. At temperatures below room temperature, transparent crystals form in it, which float in solution. It has a local antiseptic and analgesic effect, relieves inflammation. Dimexide easily passes through skin barriers and tends to carry other therapeutic components along with it, increasing their effectiveness.

    The drug is often used in combination with antibiotics, hormones, heparin and other agents dissolved in it. Dimexide is widely used in complex treatment osteoarthritis, rheumatoid arthritis, arthropathy and Bechterew's disease. It has a good therapeutic result in the treatment of injuries, with sprains and bruises, with non-healing, infected wounds. Relieves inflammation and has a resolving effect. It is used in the form of applications and compresses.

    How to dilute dimexide for compresses

    The solution is concentrated. Immediately before use, it is diluted to the required concentration, most often it is 30-50%. It depends on the nature of the disease, the sensitivity of the patient's skin and the place of application. If the application is done on the face, or the skin is hypersensitive, then the dosage cannot exceed 20%.

    Dimexide concentrate is diluted with boiled or distilled water. To enhance the analgesic effect, it is diluted with a solution of novocaine, and vegetable oil is used for use in the form of tampons. Most often, for the treatment of certain diseases, the doctor prescribes the following concentrations of Dimexide solution:

    Treatment inflammatory diseases joints and removal pain syndrome(including traumatic) is produced by 25-50% solutions.

    Do not take a compress with a solution of dimexide as a harmless remedy. The medicine is very strong, so you need to strictly observe the dosage (based on the nature of the disease) and the time of exposure. The concentrated solution causes burns. There are also serious contraindications.

    Dimexide can not be used for functional disorders of the kidneys and liver, cataracts, glaucoma, children under 12 years of age, during pregnancy. Do not forget about its ability to enhance the effect of other drugs, both medicinal and toxic. Therefore, care should be taken and compatibility with other medicinal substances should be taken into account.

    How to prepare a solution of the correct concentration

    To get a 10% solution of dimexide, you need 2 milliliters of the drug and 18 milliliters of water.

    For 20% concentration - 2 ml of dimexide and 8 ml of water.

    To get a 25% solution of the drug, you need to take 2 ml of dimexide solution and 6 ml of water.

    For a 30% solution - 6 ml of the drug and 14 ml of water.

    To get a 40% solution, you will need to take 4 ml of Dimexide solution and 6 ml of water.

    A solution of 50% concentration is obtained in a ratio of one to one. For example, 5 ml of water and 5 ml of dimexide solution.

    A concentration of 90% is 18 ml of dimexide and 2 ml of water.

    The duration of treatment with compresses based on the drug is days.

    Throat compress

    Dimexide tends to pass through everything biological membranes to the site of inflammation. It is a very powerful anti-inflammatory and antiseptic agent for the treatment of diseases of the upper respiratory tract. Such a compress warms up perfectly, relieves inflammation and dry cough that irritates the throat.

    To prepare a compress, you will need dimexide concentrate, honey, water and aloe juice.

    At home, it is more convenient to measure the amount of ingredients with a spoon.

    Take 2 tablespoons of dimexide and dilute with 1 tablespoon of water. Squeeze juice from aloe stalks, a tablespoon and add to the solution. Melt two tablespoons of honey in a water bath and add to the medicinal mixture. Heat the composition for 10 seconds in the microwave or in a water bath and apply to a wide bandage or gauze folded four times. Put a compress on the throat area and cover with cellophane. Tie a warm scarf over the top. Exposure time -3 hours. If you feel a strong burning sensation, it is better to remove the compress and rinse with warm water.

    Do the procedure daily and preferably at night, so that after you go under the covers and not overcool the warmed throat.

    Compress for bronchitis

    Compresses are very efficient way bronchitis treatment. Medicinal substances will directly penetrate to the focus of inflammation, relax the muscles of the bronchi and increase their blood supply. He needs to be treated in a timely manner, as he can take chronic form or cause other diseases.

    To prepare a compress, you need to dilute a tablespoon of dimexide solution with the same amount of boiled water. Add to it 10 ml of novocaine solution 2% and 1 ampoule of diclofenac sodium solution.

    Soak gauze folded in several layers with this composition and apply on the chest, feet or back for 40 minutes. Cover with cellophane and secure with something warm, additionally cover with a blanket. You need to do such procedures 1 time per day for a week. At elevated temperature procedure cannot be done.

    Compress on the joints

    Dimexide compresses significantly relieve pain and relieve inflammation in diseases of the musculoskeletal system: arthrosis, arthritis and others. For this, dimexide diluted to 50% is used. On knee-joint or an ankle compress is placed daily for 1 hour. The duration of treatment is 15-20 days.

    Before making a compress, you can smear the affected joint with an anti-inflammatory ointment: Dolgit, Quick-gel, Chondroxide. Dimexide transports medicinal substances from the ointment to the focus of inflammation and enhances its therapeutic effect.

    A good therapeutic effect is given by compresses that have a complex composition.

    Treatment is carried out in a course of 20 days, compresses are applied for 40-60 minutes.

    The drug is well tolerated, and even if someone does not like its smell, then everyone recognizes the effectiveness of such treatment.

    How to make a compress with Dimexide

    A compress with Dimexide is used to eliminate various dermatological, gynecological, articular pathologies, organ diseases respiratory system. During treatment, observe certain safety measures and prepare the solution strictly according to the instructions.

    Dimexide is used to treat a variety of pathologies.

    Indications and benefits

    For compresses, a concentrated solution of Dimexide is used, which contains at least 99% of the active substance - dimethyl sulfoxide. The drug has anti-inflammatory, anesthetic, antiseptic action, dissolves fibrin deposits.

    Scope of application of Dimexide:

    • inflammatory processes in the organs of the musculoskeletal system, which are accompanied by pain syndrome - osteochondrosis, arthritis, osteoarthritis, synovitis, sciatica;
    • as an anesthetic for injuries, fractures;
    • dermatological pathologies - boils, eczema, acne, scleroderma, infectious diseases caused by streptococci;
    • trophic ulcerative lesions of the epidermis, purulent processes in wounds;
    • inflammation salivary glands, lymph nodes;
    • fungal infections;
    • respiratory diseases - tonsillitis, pharyngitis, bronchitis, tonsillitis;
    • diseases of a gynecological and urological nature - colpitis, thrush, adnexitis, cervical erosion, prostatitis, cystitis.

    Dimexide is suitable for the treatment of bruises

    The drug is included complex therapy in the treatment of thrombophlebitis, lymphostasis, hemorrhoids, lupus erythematosus, it is also used in cosmetology to improve the condition of the skin and hair. Electrophoresis with Dimexide is prescribed for patients with neurological diseases who cannot take non-steroidal anti-inflammatory drugs orally.

    Application methods

    Before use, Dimexide should be diluted to the desired concentration with water, the temperature of which is 45–47 degrees, after which a piece of gauze or a thin natural fabric should be moistened in the liquid. From above, cover with a film of their polyethylene, fix everything with a bandage. The proportions of the solution, the frequency of application of the compress depend on the pathology. How long to keep lotions? The duration of the procedure is no more than an hour. For the treatment of certain diseases, dimethyl sulfoxide is combined with other drugs, which makes it possible to achieve positive dynamics as soon as possible.

    How to prepare to breed

    Dimexide must not be used undiluted to avoid burns, the solution for compresses should be prepared with gloves. The medicine should not be rubbed into the skin.

    Dimexide in gynecology

    Dimethyl sulfoxide helps with various gynecological and urological pathologies of an infectious and inflammatory nature, it is used during rehabilitation after surgery, a course radiotherapy. The drug is used for tampons and compresses - the solution must be diluted with water in a ratio of 1:5. The procedure should be carried out twice a day for a week.

    For the treatment of gynecological problems, Dimexide should be applied to tampons

    Compresses with Dimexide for diseases and injuries of the musculoskeletal system

    Dimexide is considered one of the the best means to eliminate pain and manifestations of inflammation in various pathological processes in the organs of the musculoskeletal system. It is applied to inflamed joints, bumps on the legs, it contributes to the speedy recovery from fractures of the limbs. The drug is combined with other drugs to enhance the therapeutic effect.

    Solution with Dimexide and Novocaine for pain relief

    To prepare a fast-acting remedy for local anesthesia it is necessary to dissolve 45 ml of Dimexide in 75 ml of water, add 75 ml of 2% Novocain. Soak a gauze bandage with liquid, apply it to the inflamed joint or knee, cover it with a dry thin cloth, put a layer of cotton wool 1.5-3 cm thick on top, fix everything with an elastic bandage.

    • to improve the condition with pain in the spine - with osteochondrosis of the cervical and lumbar;
    • with synovitis of the knee joint;
    • for elimination discomfort for a change in the weather.

    The procedure should be carried out every 12-24 hours, for 10-14 days.

    Dimexide helps with synovitis of the knee joint

    Solution with Dimexide and Lidocaine - first aid for bruises and injuries

    For efficient and fast elimination pain often in sports medicine, a solution based on dimethyl sulfoxide and analgesics is used. Mix 15 ml of water with 5 ml of Dimexide, add 5 ml of alcohol, an ampoule of Lidocaine or Analgin. Soak gauze with the composition, fix it on the knee, lower leg, injured limb for 40 minutes.

    • with bruises;
    • when sprained ligaments;
    • in case of a broken leg, arm - as first aid, for the speedy return of mobility after removal of the cast.

    Compress with Dimexide helps with bruises and injuries

    With a strong pain syndrome, you can prepare a solution of 5 ml of dimethyl sulfoxide, 10 ml of 0.5% Novocaine and an ampoule of Diclofenac. This medicine also helps with osteochondrosis.

    If the injury is accompanied open wounds, for anesthetic compresses, a 10% solution of dimethyl sulfoxide should be used.

    How to eliminate inflammatory processes

    If articular pathologies are accompanied inflammatory processes glucocorticosteroids should be used. To prepare the medicine, mix 30 ml of water with 50 ml of dimethyl sulfoxide, add an ampoule of Hydrocortisone. Apply the application on inflamed joints 2-3 times a day for two weeks.

    For what diseases to use:

    • with arthrosis;
    • to eliminate the manifestations of arthritis;
    • with sciatica:
    • helps with bumps on the legs.

    For compresses, a clean bandage should be used each time so as not to exceed allowable concentration solution.

    Dimexide in the treatment of dermatological pathologies

    A solution of dimethyl sulfoxide actively fights against different kind pathogenic microorganisms, accelerates the healing process, eliminates the manifestations of inflammation. For various dermatological infectious diseases the effectiveness of the drug can be observed after 3-4 days.

    Dimexide for the treatment of fungal infections

    Dimethyl sulfoxide has an analgesic, antiseptic and antimicrobial effect, which allows it to be effectively used to eliminate mycosis and onychomycosis. Applications allow you to speed up the regeneration process, quickly eliminate the main manifestations of the pathology - pain, itching.

    How to use correctly:

    1. Dilute Dimexide with water in a ratio of 1:2.
    2. Steam the affected areas in water with the addition of soda, laundry soap.
    3. Remove dead cells and the upper part of the nail plate.
    4. Soak cotton pads or small pieces of gauze with a solution, fix on inflamed areas.
    5. After half an hour, remove the application, rinse the skin with warm water.

    Dimexide will restore the nail after a fungal infection

    Treatment with a solution of dimethyl sulfoxide for acne, acne

    The strong anti-inflammatory effect of the drug helps to quickly get rid of various rashes on the face, eliminate purulent processes. Dilute dimexide with water in a ratio of 1: 5, with sensitive skin- 1:6 - moisten a gauze bandage with holes for the eyes and mouth in the liquid, apply to the skin, hold for half an hour. The only drawback is a strong corrosive smell, to get rid of it, you can add 3-5 drops of essential oil to the solution.

    Dimexide will relieve rashes and acne on the face

    Getting rid of cellulite

    Dimethyl sulfoxide has a vasoconstrictive effect, accelerates metabolic processes, so it can be effectively used to eliminate the "orange peel".

    How to breed

    Moisten gauze in the solution, wrap problem areas, apply polyethylene on top, wrap with warm cloth. Session duration - 45-50 minutes, the course consists of 10-15 procedures.

    Compresses for purulent inflammation of soft tissues

    To prevent suppuration with panaritium, Dimexide is used in the form alcohol solution- mix dimethyl sulfoxide with 70% alcohol in a ratio of 1: 4, make an application every 8 hours.

    How to use Dimexide for respiratory diseases

    Compresses with Dimexide help speed up the healing process for respiratory diseases. Applications should be placed on the chest and back, kept for 35–40 minutes, the procedure should be carried out twice a day. Relief occurs after 2-3 days, the maximum duration of the course is 2 weeks.

    How to prepare compresses:

    1. From cough, to improve sputum discharge, to eliminate pain syndrome, dilute a solution with Dimexide and Eufillin. Dissolve 15 ml of dimethyl sulfoxide in 75 ml of distilled water, add 15 ml of Mukolvan and Eufillin.
    2. With angina and tonsillitis - dissolve 30 ml of Magnesia and Dimexide in 150 ml of water, add 15 ml of Dexamethosone, 30 ml of Eufillin.
    3. With seizures bronchial asthma- Dissolve 30 ml of dimethyl sulfoxide and 15 ml of 2% novocaine in 150 ml of water, mix with one ampoule of Hydrocortisone.
    4. With tuberculosis, with pneumonia, a solution is prepared from Dimexide and Rifampicin - the finished medicine has a powerful antibacterial effect. In 100 ml of water add 25 ml of dimethyl sulfoxide, 5 ml of Rifampicin.

    For the treatment of the respiratory system, the compress should be placed on the back or chest.

    Before starting treatment with Dimexide, it is necessary to conduct a sensitivity test - dilute with water in a ratio of 1: 1, apply to the skin in the elbow bend. If within half an hour negative reactions did not appear, you can use it for treatment.

    Contraindications

    The main contraindication is individual intolerance medicinal product, hypersensitivity epidermis. The drug should be used with caution in the elderly.

    In what cases is it forbidden to use Dimexide:

    • renal and hepatic functional failure;
    • angina;
    • heart attack, cerebral stroke, coma;
    • in the presence of pronounced manifestations of atherosclerosis;
    • glaucoma, cataract.

    Dimexide is forbidden to use for glaucoma

    Subject to the instructions for use, the drug does not cause side effects. Some patients experience nausea due to the sharp garlic smell of the drug, sometimes bronchospasm develops, allergic reactions in the form of burning, redness and swelling of the skin.

    What can replace Dimexide in a compress?

    The price of Dimexide is 50–75 rubles. The drug has no structural analogues, but there are medications with the same therapeutic effect.

  • The drug Dimexide It is used very widely and not only in medical practice, but also in cosmetology. With the help of Dimexide, skin diseases, diseases of the musculoskeletal system, gynecological pathologies, etc. are successfully treated. The medicine relieves pain and inflammation, destroys pathogenic bacteria.

    Usually Dimexide solution is used in a diluted form. How to properly dilute the Dimexide solution so as not to get burned - read about this on these pages.

    The main advantage of Dimexide- its rapid penetration through the skin and mucous membranes. In this case, the drug delivers deep into the tissues - to the focus of inflammation - the medicinal substances dissolved in it. Dimexide is used externally as compresses or tampons. Before use, Dimexide should be diluted with water to obtain a solution of a certain concentration - in each specific case, its own.

    To prepare a solution of Dimexide, you need to use only two types of water - distilled and boiled.

    Before using Dimexide, you need to test yourself for the possibility of an allergic reaction to the drug. The test is done in the usual way: a few drops of a 25% aqueous solution of Dimxide are applied to the elbow bend and after half an hour a reaction on the skin is observed. If there is no reaction, you can safely use the drug. If there are sensations of itching, redness, Dimexide should not be used.

    To use Dimexide as a remedy, you need to prepare a 30-50% solution. For the treatment of eczema (diffuse streptoderma), a more concentrated solution is used - 40-90%. For purulent skin lesions, a 30-40% solution is required, for superficial burns, a 20-30% solution of Dimexide is required. For erysipelas, a 50% solution is used.

    The dilution procedure itself is as follows: you need to put on gloves, take a container, pour the required amount of Dimexidum concentrated agent into it and add distilled or boiled water to it. Make proportions based on a specific disease.

    • To obtain a 10% solution, 18 ml of water is taken, Dimexide - 2 ml.
    • To obtain a 20% solution: 8 ml of water and 2 ml of Dimexide.
    • To obtain a 25% solution: 6 ml of water and 2 ml of Dimexide.
    • To obtain a 30% solution: 14 ml of water and 6 ml of Dimexide.
    • To obtain a 40% solution: 6 ml of water and 4 ml of Dimexide.
    • To obtain a 50% solution: 5 ml of water and 5 ml of Dimexide.
    • To obtain a 90% solution: 2 ml of water and 18 ml of Dimexide.

    Instead of water, you can use vegetable oils, especially for making tampons. A gauze bandage soaked in the prepared solution is applied to the diseased area, then a compress is made on top: a plastic wrap is applied and then a natural fabric (cotton, linen, wool). The compress is left for half an hour. Treatment continues for 10 days.

    Remember that you can not rub the Dimexide solution, massage your skin with it! This can cause chemical burns to the skin.

    approximate solutions. When preparing approximate solutions, the amounts of substances that must be taken for this are calculated with little accuracy. Atomic weights of elements to simplify calculations can be taken rounded sometimes to whole units. So, for a rough calculation, the atomic weight of iron can be taken equal to 56 instead of the exact -55.847; for sulfur - 32 instead of the exact 32.064, etc.

    Substances for the preparation of approximate solutions are weighed on technochemical or technical scales.

    Fundamentally, the calculations in the preparation of solutions are exactly the same for all substances.

    The amount of the prepared solution is expressed either in units of mass (g, kg) or in units of volume (ml, l), and for each of these cases, the calculation of the amount of the dissolved substance is carried out differently.

    Example. Let it be required to prepare 1.5 kg of a 15% solution sodium chloride; pre-calculate the required amount of salt. The calculation is carried out according to the proportion:


    i.e. if 100 g of the solution contains 15 g of salt (15%), then how much will it take to prepare 1500 g of the solution?

    The calculation shows that you need to weigh 225 g of salt, then take 1500 - 225 = 1275 g. ¦

    If it is given to obtain 1.5 liters of the same solution, then in this case, according to the reference book, its density is found out, the latter is multiplied by the given volume and thus the mass of the required amount of solution is found. Thus, the density of a 15%-horo solution of sodium chloride at 15 0C is 1.184 g/cm3. Therefore, 1500 ml is



    Therefore, the amount of substance for preparing 1.5 kg and 1.5 l of solution is different.

    The calculation given above is applicable only for the preparation of solutions of anhydrous substances. If an aqueous salt is taken, for example Na2SO4-IOH2O1, then the calculation is somewhat modified, since crystallization water must also be taken into account.

    Example. Let it be necessary to prepare 2 kg of 10% Na2SO4 solution starting from Na2SO4 *10H2O.

    The molecular weight of Na2SO4 is 142.041 and Na2SO4*10H2O is 322.195, or rounded 322.20.

    The calculation is carried out first on anhydrous salt:


    Therefore, you need to take 200 g of anhydrous salt. The amount of decahydrate salt is found from the calculation:

    Water in this case must be taken: 2000 - 453.7 \u003d 1546.3 g.

    Since the solution is not always prepared in terms of anhydrous salt, then on the label, which must be stuck on the vessel with the solution, it is necessary to indicate which salt the solution is prepared from, for example, 10% Na2SO4 solution or 25% Na2SO4 * 10H2O.

    It often happens that the previously prepared solution needs to be diluted, i.e., its concentration should be reduced; solutions are diluted either by volume or by weight.

    Example. It is necessary to dilute a 20% solution of ammonium sulfate so as to obtain 2 liters of a 5% solution. We carry out the calculation in the following way. We learn from the reference book that the density of a 5% solution of (NH4) 2SO4 is 1.0287 g/cm3. Therefore, 2 liters of it should weigh 1.0287 * 2000 = 2057.4 g. This amount should contain ammonium sulfate:


    Considering that losses may occur during measuring, you need to take 462 ml and bring them to 2 liters, i.e. add 2000-462 = 1538 ml of water to them.

    If the dilution is carried out by weight, the calculation is simplified. But in general, dilution is carried out on a volume basis, since liquids, especially in large quantities, are easier to measure by volume than to weigh.

    It must be remembered that in all work, both with dissolution and dilution, one should never pour all the water into the vessel at once. Rinse with water several times the dishes in which the weighing or measuring of the desired substance was carried out, and each time this water is added to the vessel for the solution.

    When special accuracy is not required, when diluting solutions or mixing them to obtain solutions of a different concentration, you can use the following simple and quick method.

    Let us take the already analyzed case of diluting a 20% solution of ammonium sulphate to 5%. First we write like this:


    where 20 is the concentration of the solution taken, 0 is water and 5 "is the required concentration. Now we subtract 5 from 20 and write the resulting value in the lower right corner, subtracting zero from 5, we write the number in the upper right corner. Then the circuit will look like this :


    This means that you need to take 5 volumes of a 20% solution and 15 volumes of water. Of course, such a calculation is not accurate.

    If you mix two solutions of the same substance, then the scheme remains the same, only the numerical values ​​\u200b\u200bare changed. Let a 25% solution be prepared by mixing a 35% solution and a 15% solution. Then the diagram will look like this:


    i.e. you need to take 10 volumes of both solutions. This scheme gives approximate results and can be used only when special accuracy is not required. It is very important for any chemist to cultivate the habit of accuracy in calculations when necessary, and to use approximate figures in cases where this will not affect the results. work. When greater accuracy is needed when diluting solutions, the calculation is carried out using formulas.

    Let's look at some of the most important cases.

    Preparing a diluted solution. Let c be the amount of solution, m% is the concentration of the solution to be diluted to a concentration of n%. The resulting amount of dilute solution x is calculated by the formula:


    and the volume of water v for diluting the solution is calculated by the formula:


    Mixing two solutions of the same substance of different concentration to obtain a solution of a given concentration. Let by mixing a parts of an m% solution with x parts of a n% solution, you need to obtain a /% solution, then:


    precise solutions. When preparing exact solutions, the calculation of the quantities of the required substances will be checked already with a sufficient degree of accuracy. The atomic weights of the elements are taken from the table, which shows their exact values. When adding (or subtracting), use the exact value of the term with the smallest number decimal places. The remaining terms are rounded off, leaving one more decimal place after the decimal point than in the term with the least number of digits. As a result, as many digits after the decimal point are left as there are in the term with the least number of decimal places; while doing the necessary rounding. All calculations are made using logarithms, five-digit or four-digit. The calculated amounts of the substance are weighed only on an analytical balance.

    Weighing is carried out either on a watch glass or in a bottle. The weighed substance is poured into a cleanly washed volumetric flask through a clean, dry funnel in small portions. Then, from the washer, several times with small portions of water, the bnzhe or the watch glass in which the weighing was carried out is washed over the funnel. The funnel is also washed several times with distilled water.

    For pouring solid crystals or powders into a volumetric flask, it is very convenient to use the funnel shown in Fig. 349. Such funnels are made with a capacity of 3, 6, and 10 cm3. You can weigh the sample directly in these funnels (non-hygroscopic materials), having previously determined their mass. The sample from the funnel is very easily transferred to the volumetric flask. When the sample is poured, the funnel, without removing the flask from the throat, is well washed with distilled water from the wash bottle.

    As a rule, when preparing accurate solutions and transferring the solute to a volumetric flask, the solvent (for example, water) should occupy no more than half the capacity of the flask. Stopper the volumetric flask and shake until completely dissolved solid. The resulting solution is then filled up to the mark with water and mixed thoroughly.

    molar solutions. To prepare 1 liter of a 1 M solution of a substance, 1 mol of it is weighed on an analytical balance and dissolved as described above.

    Example. To prepare 1 liter of 1 M solution of silver nitrate, find in the table or calculate the molecular weight of AgNO3, it is equal to 169.875. Salt is weighed and dissolved in water.

    If you need to prepare a more dilute solution (0.1 or 0.01 M), weigh out respectively 0.1 or 0.01 mol of salt.

    If you need to prepare less than 1 liter of solution, then dissolve a correspondingly smaller amount of salt in the corresponding volume of water.

    Normal solutions are prepared in a similar way, only weighing not 1 mole, but 1 gram equivalent of a solid.

    If you need to prepare a semi-normal or decinormal solution, take 0.5 or 0.1 gram equivalent, respectively. When preparing not 1 liter of solution, but less, for example 100 or 250 ml, then take 1/10 or 1/4 of the amount of the substance required to prepare 1 liter and dissolve in the appropriate volume of water.


    Fig 349. Funnels for pouring a sample into a flask.

    After preparing the solution, it must be checked by titration with an appropriate solution of another substance with a known normality. The prepared solution may not correspond exactly to the normality that is given. In such cases, an amendment is sometimes introduced.

    In production laboratories, accurate solutions are sometimes prepared “by the substance to be determined”. The use of such solutions facilitates calculations in analyzes, since it is enough to multiply the volume of the solution used for titration by the titer of the solution in order to obtain the content of the desired substance (in g) in the amount of any solution taken for analysis.

    When preparing a titrated solution for the analyte, the calculation is also carried out according to the gram equivalent of the dissolved substance, using the formula:


    Example. Let it be necessary to prepare 3 liters of potassium permanganate solution with an iron titer of 0.0050 g / ml. The gram equivalent of KMnO4 is 31.61 and the gram equivalent of Fe is 55.847.

    We calculate according to the above formula:


    standard solutions. Standard solutions are called solutions with different, precisely defined concentrations used in colorimetry, for example, solutions containing 0.1, 0.01, 0.001 mg, etc. of a solute in 1 ml.

    In addition to colorimetric analysis, such solutions are needed when determining pH, for nephelometric determinations, etc. Sometimes standard solutions are stored in sealed ampoules, but more often they have to be prepared immediately before use. Standard solutions are prepared in a volume of no more than 1 liter, and more often - less.Only with a large consumption of the standard solution, it is possible to prepare several liters of it, and then on condition that the standard solution will not be stored for a long time.

    The amount of substance (in g) required to obtain such solutions is calculated by the formula:


    Example. It is necessary to prepare standard solutions of CuSO4 5H2O for the colorimetric determination of copper, and 1 ml of the first solution should contain 1 mg of copper, the second - 0.1 mg, the third - 0.01 mg, the fourth - 0.001 mg. First prepare a sufficient amount of the first solution, for example 100 ml.