TILOSIN 50
Name (lat.)
Composition and form of release
Injectable 5% solution, 1 ml of which contains 50 mg of tylosin in the form of a base. Tylosin 50's appearance is a transparent, light yellow liquid. Bottles of 20 ml, 50 ml and 100 ml.
Pharmacological properties
Tylosin is active against most gram-positive and some gram-negative bacteria, including streptococci, leptospira, corynebacteria, clostridia, erysipelotrix, pasteurella, chlamydia, treponema, chiodysentery, spirochetes and mycoplasmas. When administered intramuscularly, the antibiotic is rapidly resorbed and reaches maximum concentrations in body tissues approximately 1 hour after administration. The therapeutic level of the antibiotic in the tissues is maintained for at least 20 hours. Tylosin is excreted from the body mainly in urine and milk.
Indications
Prescribed for the treatment of bronchopneumonia in cattle and small ruminants, pigs, dogs and cats; bovine mastitis; enzootic pneumonia, arthritis, dysentery, atrophic rhinitis and swine erysipelas; infectious agalactia of sheep and goats, as well as secondary infections in viral diseases.
Doses and method of administration
The drug is administered intramuscularly once a day for 3 - 5 days in the following doses: cattle - 5 - 10 mg / kg animal weight, pigs - 10 mg / kg animal weight, sheep and goats - 10 - 12 mg / kg weight animal.
Side effects
Allergic reactions in pigs in the form of erythema, pruritus, respiratory symptoms are very rare, mild edema with a slight prolapse of the rectum, which quickly disappear after discontinuation of the drug.
Contraindications
It is not recommended to use tylosin simultaneously with penicillin (especially with ampicillin and oxacillin), cephalosporins and lincomycin due to a pronounced decrease in the antibacterial effect of tylosin, as well as in case of hypersensitivity to the drug's constituents.
special instructions
Slaughter of animals for meat, which was used Tylosin 50, is allowed 8 days after stopping the administration of the drug. The meat of animals that were forcedly killed before the expiration of the specified period is used for feeding carnivores or for the production of meat and bone meal. Milk obtained from animals during the period of application of Tylosin 50 and before the expiration of 4 days after the last administration of the drug should not be used for food purposes. Such milk can be used to feed animals.
Storage conditions
List B. In a dry, dark place at a temperature of 10 to 25 ° C. Shelf life is 2 years.
It is a highly effective antibiotic from the group of macrolides, which make up a component that actively acts on gram-positive and gram-negative bacteria.
Description and composition of Tylosin 50
Tylosin is produced in hermetically sealed glass vials, which are sealed with rolled up aluminum caps and rubber stoppers. The drug was developed specifically for use in veterinary medicine.The drug inhibits bacterial protein synthesis by binding the constituent component to the active substance using ribose. In terms of the degree of effect on the animal organism, the drug is not very dangerous. Its leaving component is excreted from the body with bile secretion and urine, in females - with milk and during lactation.
Did you know? The drug Tylosin 50 is low-toxic, due to which it gained wide popularity.
Biological properties of the drug, how Tylosin 50 works
The following pharmacological properties drug:
antibacterial action. The drug is classified as a macrolide antibiotic with a pronounced antibacterial effect, which spreads to animals different types;
- effect on gram-negative and gram-positive bacteria, including staphylococcus and streptococcus, which cause pneumonia in animals;
- inhibition of protein synthesis in pathological microorganisms;
- due to intramuscular administration, rapid absorption in the body. The peak of activity is observed one hour after injection;
- has a positive effect on the body during the day, after which it is simply excreted from the body with urine and bile.
- bronchopneumonia;
- mastitis;
- enzootic pneumonia;
- arthritis;
- dysentery;
- atrophic rhinitis;
- infectious agalactia;
- secondary infections from viral diseases.
- for a cattle scor - 0.1-0.2 ml of the substance;
- for pigs - 0.2 ml;
- for goats, sheep - 0.2-0.024 ml;
For the appointment of the drug Tylosin 50, any pathology of bacterial etiology can serve, the dose and method of administration may differ. The instructions contain information on methods of treatment certain types animals.
Important! The medicine Tylosin is equally effective in treating infections of cattle, dogs, cats, birds and other animals.
When to use the drug, indications for use
Let's take a look at Tylosin 50 and its instructions for use in veterinary medicine.
Tylosin is used for therapy and prevention infectious diseases, which are caused by pathogens sensitive to Tylosin. Also, the purpose of the drug is the prevention and treatment of secondary infections during viral diseases. The drug Tylosin 50 has different effects on animal organisms, for example, the instructions for use for pigs will differ from the instructions for another animal.
The drug is prescribed for the treatment of such diseases:
How to take the drug, animal species and dosage
As mentioned above, the instructions for use of the drug Tylosin 50, for example, for chickens, differ from the instructions for other animals. But there is one general rule - the need intramuscular injection the drug once a day.
Important! During repeated use, you need to change the injection site.
Each type of animal has its own dosage of the drug:
Contraindications for the use of the drug and side effects
Tylosin most often has no side effects, however, with individual hypersensitivity of the animal, an allergic reaction is still possible. Pigs are rarely prone to erythema, respiratory symptoms or itching. However, these reactions go away quickly on their own. If you think that the side effects are too strong, we recommend that you stop treatment with the drug.
Important! The duration of treatment with Tylosin should not exceed three days.
Animals are allowed to be slaughtered no earlier than eight days after the drug is used. Milk is allowed for consumption after four days from the last use of the drug.After Tylosin has been used to treat chickens, eggs are also prohibited from eating until the drug is completely eliminated from the body.
Tylosin 50: storage rules and precautions when working with the drug
When working with any veterinary drug, you should definitely worry about your personal safety and prevent the drug from getting into circulatory system... A person must have some special skills and knowledge, when working with Tylosin it will be useful to know how to calculate the dose for the animal, for example, what dosage is needed for pigeons. When working directly with animals, it is important to know how to hold it properly and where it is best to inject. Due to the restless behavior of the animal, attempts to escape, there is a danger of accidentally piercing the skin with a needle, and not the patient.
Important! In the event of a puncture of your skin, it is important to take appropriate action, because the needle could not become sterile, and this could lead to infection.
The drug Tylosin 50, in accordance with the instructions, provides for work exclusively with gloves. If Tylosin comes into contact with mucous or exposed skin, it must be washed immediately. At the end of the injection procedure, hands should be washed with soap and wiped dry.
Tylosin 50 and 200 - veterinary drugs wide range impact. In veterinary medicine, this antibiotic is used to treat infectious diseases. Due to the strong effect of Tylosin, the instruction recommends adhering to the dosage precisely for different types of animals.
Description and properties
The drug is called active substance - tylosin. AT international classification it is a macrolide antibiotic. The substance is specially developed for the needs of veterinary medicine. It actively destroys most groups of microorganisms. Among them are chlamydia, spirochetes, mycoplasmas and other causative agents of infectious diseases in animals.
Another medicine eliminates large and simple viruses. It suppresses protein synthesis at the cellular level. As a result, the bacteria or virus loses the ability to grow and divide. Above the speed and safety of tylosin absorption into the blood, the auxiliary composition of the veterinary drug components works:
- propanediol;
- benzyl alcohol;
- injection liquid.
Depending on the concentration, manufacturers produce two forms of the drug:
- Tylosin 50 (5%). In 1 ml - 50 mg.
- Tylosin 200 (20%). 1 ml contains 200 mg.
Both varieties are a thick, transparent solution for intramuscular injection with a yellow tint. The medicine is available in hermetically sealed glass vials with a volume of 20-100 ml. The smell is specific, not harsh.
The structure of Tylosin allows it to be rapidly absorbed into the bloodstream by transit through the muscle. The active substance reaches the greatest strength in the tissues of the body by the end of the first hour. The therapeutic effect lasts up to 1 day. The antibiotic is excreted for 3 days. with bile, urine and milk (in lactating individuals).
Indications and contraindications
With the help of the tool, the instructions for use allow you to treat pets and all groups of agricultural animals, as well as poultry. Laboratory research confirmed the stability of the antibiotic effect and its relative safety.
The solution is used for therapy:
- pneumonia of various types;
- arthritis;
- chronic rhinitis in pigs;
- dysentery;
- agalactia of goats and sheep.
Attention! The drug helps in the treatment of other diseases as well. The appointment should be made exclusively by a veterinarian.
Contraindications from the instructions for use:
- allergic effect;
- intolerance to the components.
All this is expressed in the form of a rash, local irritation, edema at the injection point. In pigs, intestinal prolapse is possible. You should immediately stop using the medicine, wait until the symptoms disappear. Experiments have not shown side effects in case of overdose, but there is a risk of such phenomena.
- It is undesirable to use it simultaneously with other antibiotics.
- It is allowed to eat animal meat no earlier than after 8 days. since the last time they took the medicine. The product obtained before this period can be determined for feed to other animals.
- Milk can be consumed starting from 5 days. after the last dose of Tylosin.
- Avoid getting the solution on the mucous membrane. Wear gloves.
- Tylosin is administered to pregnant and lactating females under the supervision of a veterinarian. The drug is stored according to the standard procedure at a temperature of + 10 ... + 25 ° C. Expiration date - no more than 18 months. from the date of production. Once opened, the solution should be used within 30 days.
Dosage features
The rates for injection according to the instructions for use are calculated based on the weight of the pet:
Attention! Pharmacists did not find any decrease in effectiveness after the first dose of the drug.
The solution is given orally to the bird instead of injections. To do this, mix it with water. Better to use Tylosin 200. Mix 5 mg in 10 liters of drink. Let's feathered in the usual way.
Despite the antibiotic status, the drug has a gentle effect on the animal's body. The medicine is appreciated by specialists for a wide range of tasks to be solved, affordable cost and speed of elimination from the body. And yet it remains an antibiotic, so it must be used strictly as directed by a doctor.
What antibiotics have you used for animals?
Tylosin: video
Tylosin is a broad-spectrum veterinary antibiotic used to treat pathologies caused by gram-positive and gram-negative bacteria in cats. It is highly effective, although it is used less often for small domestic animals than for cattle and pigs.
An antibacterial agent is produced in the form of a solution for injection. The antibiotic is produced by different pharmacological companies, so you can find different packages in pharmacies. Outwardly, the solution is clear, although it has a light yellow tint. It has a slightly viscous consistency.
For packing, bottles made of transparent or dark glass are used. To maintain tightness, they are sealed with rubber stoppers, which are rolled up with aluminum caps. Vials come in different sizes: 20, 50 and 100 ml. In most cases, it is wise for cats to buy small vials.
The active component of the drug is the substance of the same name - tylosin. The antibiotic in pharmacies is found in two versions - Tylosin 50 and Tylosin 200. The only difference in the content of the active substance is 50 and 200 mg per 1 ml of solution, respectively. In both cases, auxiliary components are also included:
- gasoline alcohol;
- purified water;
- propanediol.
Note! For cats it is recommended to use the drug with the index "50". The concentration of the active substance in it is less, and therefore it is easier to calculate the correct dose for a small animal, thereby preventing an overdose.
Follow special conditions when storing the medicinal product is not required. The air temperature should be between 10 and 25˚C. After opening the bottle, the injection solution can be used only within 28 days, after which it must be disposed of.
Pharmacological properties
Tylosin has pronounced antibacterial properties. The drug, developed specifically for animals, is effective against the following types of pathogenic microorganisms:
- hemophilic infections;
- streptococci;
- staphylococci;
- mycoplasma;
- leptospira;
- chlamydia;
- pasteurellum;
- corynobacteria, etc.
The principle of action of the active substance is to block bacterial protein synthesis. The antibiotic is rapidly absorbed and just an hour after injection, its concentration in the tissues reaches maximum value... The action of the drug lasts for 20-24 hours. Tylosin is excreted from the body mainly with bile and urine. In lactating animals, the active substance is able to penetrate into milk.
According to the degree of exposure, the drug belongs to low-hazard substances. Subject to the recommended doses and the regimen of use, it is well tolerated by animals, does not cause local irritating reactions or addiction.
The cost
When buying Tylosin 50 for cats, please note that the price depends on the volume of the package:
- 20 ml - 48-60 rubles;
- 50 ml - 115-130 rubles;
- 100 ml - 140-180 rubles
The cost of Tylosin 200 is slightly higher. For a bottle with a capacity of 20 ml, you will have to pay about 85-90 rubles, and a package for 50 ml - 150-160 rubles. You can buy the medicine at any veterinary pharmacy or clinic. An antibiotic is also available at many online pet pharmacies.
You can now view the current price of the drug and buy it right here:
Indications for use
According to the instructions for use, Tylosin is prescribed for cats in the treatment of the following pathologies:
- pneumonia;
- tracheitis;
- bronchitis;
- other diseases of the respiratory system;
- arthrosis and arthritis;
- inflammatory processes of the genitourinary system, in particular mastitis;
- mycoplasmosis;
- chlamydia;
- dysentery, etc.
Also, the drug is used for secondary infections that accompany viral diseases... Sometimes an antibiotic is prescribed for purulent wounds and inflammatory processes caused by harmful microorganisms.
Instructions for use
Animals are injected with an antibacterial agent only intramuscularly. Subcutaneous administration of the drug may cause inflammatory process and necrosis at the injection site. According to the instructions for use, the dosage of Tylosin 50 for cats is calculated taking into account the weight - 0.1-0.2 ml per 1 kg of body weight. The exact dose should be determined by the doctor, taking into account the degree of development of the disease, the existing symptoms, possible complications and other factors. Tylosin 200 for cats is rarely used due to the high concentration of the active substance, but if for some reason it is used, the dosage is calculated as follows - 0.025-0.05 ml per 1 kg of body weight.
The drug should be injected once a day. The duration of treatment is from 3 to 7 days, depending on the symptoms and the severity of the disease. It is not recommended to skip the injections, as this leads to a decrease in the effectiveness of the antibacterial agent.
Note! You need to inject the drug for the entire course prescribed by the doctor. You should not stop treatment if the animal's condition has improved. In this case, the risk of re-development of pathology or the appearance of complications increases.
Contraindications and side effects
An antibiotic is prohibited for animals that have an individual intolerance to the components, in particular tylosin. In this case, it is worth choosing another antibacterial agent for treatment.
The drug should be taken with caution for lactating animals. Active substance is able to penetrate into milk, and with it into the body of kittens. Sometimes this leads to severe dysbiosis, which can manifest as loose stools and other unpleasant symptoms. In each case, the risk to kittens and mother is assessed in individually... Use the medicine for lactating cats only under the supervision of a doctor.
Note! Tylosin categorically cannot be combined with penicillin antibiotics and other antibacterial agents. In this case, the risk of occurrence allergic reactions.
In case of intolerance, respiratory diseases, itching, redness and other allergic reactions may occur. To prevent them, the antibiotic is combined with anti-allergenic agents (Tavegil, Suprastin, Diazolin, etc.). In rare cases, loose stools or other malfunctions may appear gastrointestinal tract... In most cases, the drug is well tolerated by cats and does not cause side effects.
Advantages and disadvantages
Tylosin is considered one of the safest antibiotics for animals and cats in particular. It has been designed with pets in mind. Its main advantages include the following:
- High efficiency. The animal gets better after 1-2 injections.
- A wide range of actions. The drug can be used for diseases of the respiratory, genitourinary and other systems, musculoskeletal system, suppuration of soft tissues. The active substance acts on various harmful bacteria.
- Packaging volumes. It is easy to select a bottle, taking into account the duration of the treatment, the weight of the animal and other factors.
- A minimum of contraindications. Medicine approved for use by cats different ages and rocks.
- Safety. When the recommended doses are observed, side effects rarely occur.
The disadvantages include the need to do intramuscular injections. If you have no experience, you will have to take your pet to the clinic every day, and this can be stressful. Tylosin has no other significant drawbacks, but you should not use it without a doctor's prescription.
"Tylosin 50" and "Tylosin 200" are drugs belonging to the group of antibacterial agents used in veterinary medicine in the treatment of pulmonary and other pathologies of bacterial origin. Tylosin was included in veterinary reference books in 2013 and has been successfully used to treat pets, birds, cattle (small and large) and pigs.
Dosage forms and composition
"Tylosin 50" is an injection solution used intramuscularly. One milliliter of a viscous yellowish liquid contains 50 mg of the active (base) substance.
As additional ingredients, the medicine includes:
- propanediol;
- water;
- benzyl alcohol.
Glass vials with medicine can be 20, 50 and 100 ml in volume, sealed with a cork, and closed on top with an aluminum cap.
Pharmacological properties
The drug "Tylosin" is an antibacterial agent from the macrolide group. Highly active against gram-positive and some g ra-negative microorganisms: Chlamydia spp, Escherichia coli., Mycoplasma spp, Bacillus anthracis, Corynebacterium spp, Pasteurella, Erysipelothrix spp., Haemophilus spp., Streptococcus, Treponema, Staphylococcus spp.
The mechanism of action of the drug is the formation of a complex of 50s-subunits of ribosomes and, as a consequence, suppression of protein synthesis in bacterial cells (i.e. the drug "works" as a bacteriostatic).
When intramuscular injection "Tylosin" is absorbed quickly, the maximum concentration of the drug in the tissues is determined already one hour after the injection. The therapeutic concentration of "Tylosin" in the body of the animal is maintained for 20-24 hours. After that it is excreted with bile and urine, and in lactating individuals - with milk.
In accordance with GOST 12 .1.007−76, the drug belongs to the 4th hazard class, that is, low-hazard substances, which makes the drug so popular in veterinary medicine.
Indications for use
In accordance with the instructions of the drug, "Tylosin" is indicated for:
- the presence of secondary infections that are a complication of viral pathologies;
- bronchopneumonia in dogs, cattle (both large and small), cats, pigs;
- agalactia in goats and sheep caused by infectious agents;
- mastitis in cattle (large);
- dysentery;
- arthritis;
- enzootic pneumonia;
- atrophic rhinitis in pigs.
Instructions and dosage
The drug is administered exclusively intramuscularly once a day. The course of therapy, as a rule, is 5 days - a week. It is recommended that the injection site be changed to prevent hematomas and inflammation.
According to the instructions "Tylosin 50", the following dosages are recommended for each kilogram of animal weight:
- cats, dogs - 0.1-0.2 milliliters;
- small cattle (goats, sheep) - 0.2-0.24 milliliters;
- pigs - 0.2 milliliters;
- calves, cattle - 0.1-0.2 milliliters.
Tylosin 200 is prescribed in the following dosages (for each kilogram of mass):
- cats, dogs - 0.025-0.05 ml;
- pigs - 0.05 ml;
- cattle (small) - 0.05-0.06 ml;
- calves, cattle - 0.025−0.05 ml.
In case of a pass at the reception one or more doses the introduction of the drug must be resumed according to the same scheme and in the same dosages.
In case of independent use of the drug (without the knowledge of the veterinarian), the minimum therapeutic dose should be used.
If undesirable effects occur, the agent is canceled, and the animal is consulted with a veterinarian. Most of side effects passes on its own without special treatment.
Benefits of the drug
Tylosin is a popular antibiotic in veterinary medicine. Pros:
- a wide range of actions;
- high efficiency in the treatment of animals of various types;
- ease of use;
- low cost;
- safety;
- rapid excretion from the body;
- application once a day;
- in case of missed administration, it is not necessary to increase the dose (treatment is continued according to the same scheme).
Contraindications and side effects
A contraindication to the prescription of the drug is the presence of intolerance to any of the components of the drug in the animal.
When using "Tylosin" in the recommended dosages (see instructions for use of "Tylosin 50" in veterinary medicine), complications and unwanted side effects, as a rule, do not occur. Occasionally, pigs may experience allergic reactions, manifested by slight edema, itching, erythema, respiratory symptoms and incomplete rectal prolapse. However, they all disappear without a trace after drug withdrawal.
Overdose symptoms are unknown.
Application features
- For pregnant and lactating individuals, the drug is used very carefully and strictly under the supervision of a veterinarian.
- It is undesirable to combine the drug with others antibacterial agents from the group of penicillins (especially with oxacillin and ampicillin), cephalosporins and lincomycin, due to a pronounced decrease in the antibacterial properties of "Tylosin".
- Slaughter of pigs and cattle treated with the drug is allowed already on the eighth day after the last injection. In the event of forced slaughter before the expiration of this period, the meat is not suitable for humans and can be used as animal feed.
- It is prohibited to use milk that was obtained from an animal during the use of the drug and until the fourth day after the last injection for food purposes. However, it can be used to feed livestock and other animals.
Preventive measures and analogues
- During the use of "Tylosin 50" and "Tylosin 200" it is necessary to adhere to general rules safety and personal hygiene measures that are prescribed when working with any veterinary drugs. When injecting, it is forbidden to eat and drink, smoke. After completing the work, wash your hands in warm water with soap.
- People who have individual sensitivity to the constituents of the drug should not allow direct contact with the drug.
- In case of contact with the antibiotic mucous membranes or skin, the damaged area should be rinsed with running water. If you experience allergic reactions or if Tylosin gets into the human body, you should immediately consult a doctor (preferably a label and instructions for the drug).
- Used / empty vials should not be used in households, they should be disposed of with other waste.
The drug should be stored in a closed container in a dark, dry place with an air temperature of 10-25 degrees. The shelf life of "Tylosin" is 24 months, and after opening - 1 month.
- "Farmazin";
- "Tilomag";
- Tilanik;
- Tilovet.
