Lazolvan side effects in adults. Lazolvan - instructions for use. Special instructions and interactions with other drugs

The popular medicine Lazolvan, for what cough is it used, this question worries a large number of of people.

A cough may indicate the presence of some kind of disease or that the body is trying to get rid of foreign particles that have entered the respiratory tract (usually dust). It is impossible to cure a symptom until the root of the problem is found - the disease that causes it. There are many medications that help eliminate cough, but their effectiveness will be high only if the cause of its occurrence is eliminated.

A dry cough is paroxysmal and painful. In this case, fighting a virus or bacteria, the bronchi begin to produce several times more sputum; it does not have time to be eliminated from the body, accumulates and thickens. Very often, patients with a dry cough hear wheezing during inhalation and are unable to cough up sputum.

On a note! During treatment, it is important to transform a dry cough into a wet one. Wet cough much easier to tolerate.

Sputum separation is not difficult, she almost always coughs up.

Types of cough and causes of its occurrence

Causes of occurrence coughing attacks many, the most basic ones are given below:

  1. Diseases of the upper respiratory tract caused by viruses or bacteria (whooping cough, bronchitis, ARVI, laryngitis, tonsillitis and others).
  2. Bronchial asthma, which affects about 250 million people around the world. Its main symptoms are a dry cough, heavy breathing and shortness of breath even with minor physical exertion.
  3. Bronchiectasis can be congenital or acquired, as a complication after tuberculosis or chronic bronchitis. Deformed bronchi cannot cope with the removal of sputum, and a wet cough occurs.
  4. Smoking, because the bronchi cannot cope with the removal of tobacco smoke and toxins. As a result, phlegm accumulates, and the smoker begins to suffer from a wet, lingering cough that gets worse in the morning. Smoking is a major factor in chronic obstructive pulmonary disease (COPD), which attacks the lung tissue and restricts airflow.
  5. Heart failure can be a factor in the development of chronic bronchitis.
  6. Allergic reactions caused by dust, pollen, and during sleep by feather pillows and other irritants.
  7. Underdevelopment of the lungs that occurs in children early age(4–5 years old). This phenomenon occurs due to the fact that the child’s body develops faster than his lungs, as a result they do not have time to cope with the load. There is nothing wrong with this; the older the child gets, the faster the balance of organ development is restored.

To solve every problem you need special approach. It is better not to self-medicate and get checked by a highly qualified specialist. Delayed treatment leads to more severe complications For example, bronchitis can very quickly turn into pneumonia.

Lazolvan - indications, contraindications and side effects

It is relatively inexpensive and effective medicine against cough attacks. Available in two forms - syrup and tablets. It has an expectorant and mucolytic effect. This drug thins thickened mucus without changing its volume and helps remove it from the respiratory tract.

For what cough should you take Lazolvan? The main indications causing dry and moist cough, are all the diseases listed above: acute and chronic bronchitis, pneumonia, COPD, bronchial asthma, as well as bronchiectasis.

Lazolvan has quite a few contraindications. It is strictly forbidden to use it during the first trimester of pregnancy, nursing mothers, people with hereditary fructose intolerance and hypersensitivity to the components of the medicine (ambroxol and others). Pregnant women in the second and third trimester and people with kidney or liver failure should be careful when using the drug; before using the drug, you should consult a doctor.

Contraindications for treating children depend on the form of the medicine. Lazolvan in tablet form is prohibited for use in early childhood and adolescence (under 18 years of age). The syrup can be used from 6 years of age.

Sometimes the use of Lazolvan can cause some side effects:

  • disruption gastrointestinal tract(abdominal pain, nausea, vomiting or diarrhea);
  • disruption of taste buds;
  • allergic reactions, such as rash, urticaria, itching, angioedema and hypersensitivity.

Lazolvan does not combine with all medications. Therefore, you need to carefully read the instructions. Since this drug has a mucolytic and expectorant effect, it is incompatible with antitussive drugs. Incorrect use of these medications may make it difficult to separate and cough up mucus.

Lazolvan tablets - treatment of cough in adults and children

Adults are prescribed Lazolvan for any cough; if it is dry, then the medicine helps turn it into a wet one, and if the cough is initially wet, then the medicine promotes better sputum discharge. You can take it in any form, but tablets are the most convenient for adults. They are easily absorbed in the stomach, then enter the blood and bronchial mucosa, and are excreted through the kidneys.

Important! Only your doctor can prescribe the use of this drug. This is due to the fact that Lazolvan eliminates only the symptom – cough, but not the cause of the disease.

Often, antibiotics are also prescribed to treat respiratory diseases. Only complex treatment can overcome the disease. Therefore, if you are trying to cope with the disease on your own, carefully monitor your health; if there is no relief within a week, it is strongly recommended that you consult a specialist.

Lazolvan should be taken one tablet (30 mg) three times a day. If you need to enhance the therapeutic effect, take 2 tablets (60 mg) twice a day. The tablet must be taken with water before or after meals.

In isolated cases, due to a medical error or overdose, abdominal pain, nausea, vomiting, and dyspepsia occurred. When such side effects In the first two hours of using the drug, it is necessary to induce artificial vomiting or perform gastric lavage.

Lazolvan syrup - treatment of cough in adults and children

Lazolvan syrup is used for any cough - wet and dry. In addition, it is more convenient to use when treating children. Relief comes after taking the syrup and lasts up to 6–12 hours. Lazolvan very quickly eliminates a dry cough, turning it into a wet one. Then it removes mucus from the bronchi and improves coughing.

The use of Lazolvan in the form of syrup (15 mg/5 ml) does not depend on food intake. Adults and children over 12 years old are recommended to drink 10 ml three times a day, children from 6 to 12 years old - 5 ml twice or thrice a day. Although the syrup is prohibited for children under 6 years of age, in some cases it can be prescribed by a doctor, then children from 2 to 6 years old take 2.5 mg three times a day, and children under 2 years old take 2.5 mg twice a day .

Lazolvan syrup (30 mg/5 ml) is prescribed for any type of cough for adults and children over 12 years of age, 5 ml three times a day, and for children from 6 to 12 years old - 2.5 mg twice or three times a day.

You should not self-medicate, especially when treating children. Before taking syrup, consult your doctor. Do not forget about the shelf life of the drug - 3 years. Store it in a cool place out of the reach of children, making sure the lid of the medicine is tightly closed before doing so.

Children are more sensitive to many components of drugs, as well as food and liquids consumed with drugs. Therefore, when taking various medications (including Lazolvan), you must adhere to a few simple rules:

  1. Take medications with water only. Even mineral or carbonated water, interacting with the drug, can cause chemical reaction. You should also not drink tea, juice, etc.
  2. While taking medications and for some time after, drinking alcohol is prohibited.
  3. Take medications according to the instructions - if the tablet is coated, you must swallow it; if it is for resorption, you do not need to chew it.
  4. Pay attention to the time of taking the medicine - before or after meals. In some cases, the time of taking the drug does not matter much. Do not ignore the recommendations if you need to eat before using the drug.
  5. Follow the correct dosages.

When treating, you should choose a form of medication that will provide best action. Syrups are often preferred because they are absorbed faster than tablets and produce best effect. The tablets accumulate in the stomach and irritate the mucous membrane, which leads to some discomfort.

Inhalations using Lazolvan

Inhalation is effective remedy combat irritating and tiresome cough. Today there are many inhalers and special solutions. When carrying out inhalations, you must adhere to the following recommendations:

  1. It is prohibited to perform the procedure when elevated temperature body, nosebleeds and people with cardiovascular diseases.
  2. Inhalations should be carried out at least 1–1.5 hours after meals.
  3. During inhalation you need to breathe calmly and measuredly.
  4. After inhalation, it is better not to talk and eat food at least an hour later.
  5. The solution must be diluted under sterile conditions, so the use of raw water is prohibited.
  6. After inhalation, the solution must not be reused.
  7. Young children must wear a special mask during inhalation.

The question is often asked about what kind of cough is inhaled with Lazolvan? Mainly for dry, tedious cough. The procedure is much more effective than the use of syrups and tablets, since when the solution is inhaled, the medicine immediately reaches the respiratory tract and is absorbed more quickly into the bronchial mucosa. Relief from the drug comes almost immediately.

Currently, a special device is used for inhalation - a nebulizer. It is used on infants and adults by atomizing the medicine into tiny particles. Features of using inhalation with Lazolvan:

  1. He is being divorced from saline solution(in equal proportions) and warmed up to body temperature.
  2. It is not advisable to carry out inhalations in evening time, since Lazolvan has an expectorant effect and can increase coughing attacks at night.
  3. The procedure cannot be carried out for more than 5 days; if relief does not occur, immediately contact a specialist.
  4. Children receive inhalations using any nebulizer, but not a steam one. Ultrasonic or compressor ones are often used.

Important! If an adult or child is suffering bronchial asthma, before the procedure, you must take bronchodilators. Otherwise, bronchospasm may occur.

How to use the medicine?

Inhalations with Lazolvan are done for any cough, but there are some peculiarities. After carrying out the procedure with this drug and achieving sputum separation, anti-inflammatory drugs are used. Sometimes several drugs are used simultaneously for more effective results. Lazolvan does not combine with all medications, so inhalations with Lazolvan and Berodual are often used.

Lazolvan is an effective mucolytic and expectorant. Before using it, you should definitely consult a doctor, as it has some side effects and contraindications. We must not forget that this remedy only relieves the symptom, but does not eliminate the cause of the disease.

What kind of cough is Lazolvan used for - dry or wet? Initially, this drug dilutes accumulated mucus in the bronchi and lungs, then improves its clearance, that is, turns a dry cough into a wet one, and then stimulates the process of clearing the airways from excess mucus.

Complex treatment using Lazolvan will help you overcome the disease. Value your health.

Instructions

Compound

Syrup 15 mg/5 ml: 5 ml of syrup contains the active substance – ambroxol hydrochloride 15 mg; excipients - benzoic acid (E210), hydroxyethylcellulose, acesulfame potassium (E950), non-crystallizing liquid sorbitol (E420), glycerin 85% (E422), “Wild berries” flavor PHL-132195, “Vanilla” flavor 201629, purified water.

Syrup 30 mg/5 ml: 5 ml of syrup contains the active substance - ambroxol hydrochloride 30 mg; excipients – benzoic acid (E210), hydroxyethylcellulose, acesulfame potassium (E950), non-crystallizing liquid sorbitol (E420), glycerin 85% (E422), “Strawberry and cream” flavor PHL-132200, “Vanilla” flavor 201629, purified water.

Description

Transparent or almost transparent, colorless or almost colorless, slightly viscous syrup.

Pharmacotherapeutic group

Medicines used for coughs and colds. Mucolytic agents. ATX code: R05CB06.

Pharmacological propertiesPharmacodynamics

In to clinical studies Ambroxol hydrochloride, the active ingredient in Lazolvan, has been shown to increase secretion in respiratory tract, enhances the synthesis of pulmonary surfactant and stimulates ciliary activity. It also increases the secretion of surfactants as a result of a direct effect on type II pneumocytes located in the alveoli and Clara cells in the bronchioles, and also stimulates the activity of the ciliated epithelium. The described effects cause a decrease in sputum viscosity and an improvement in sputum transport (mucociliary clearance). Improved mucociliary clearance has been demonstrated in clinical pharmacological studies. Increased secretion of the serous component of sputum and increased mucociliary clearance promote sputum discharge and relieve cough. In addition, in patients with chronic bronchitis and/or chronic obstructive pulmonary disease (COPD), the number of exacerbations of the disease is reduced.

In patients with COPD who took LAZOLVAN extended-release capsules 75 mg for 6 months, by the end of the 2nd month of treatment, a significant reduction in exacerbations was recorded compared to placebo. Patients in the LAZOLVAN group had a significant decrease in the number of days of illness and a decrease in the number of days taken antibacterial drugs. Also, in the LAZOLVAN group, compared with placebo, there was a statistically significant improvement in the assessed symptoms, such as difficulty in sputum expectoration, cough, shortness of breath and auscultatory symptoms.

The local analgesic effect of ambroxol hydrochloride was observed in studies conducted in a rabbit eye model and is likely due to the drug blocking sodium channels. In vitro tests showed that the drug reversibly and dose-dependently blocks neuronal sodium channels.

In vitro, ambroxol hydrochloride was found to have an anti-inflammatory effect. In in vitro tests, it significantly reduced the release of cytokines from circulating and tissue mononuclear and polymorphonuclear cells.

Clinical studies conducted in patients with sore throat showed that ambroxol hydrochloride 20 mg lozenges significantly reduced pain and redness in the throat.

These pharmacological properties confirm the additional observation from clinical efficacy studies that ambroxol inhalation provides rapid pain relief when used in the treatment of upper respiratory tract disorders.

The simultaneous use of ambroxol hydrochloride with antibiotics (amoxicillin, cefuroxime, erythromycin and doxycycline) increases the concentration of antibiotics in the lung tissue. To date, the clinical significance of this effect has not been proven.

Pharmacokinetics

Suction

Absorption of oral forms of immediate release is high and complete, the time to reach maximum concentration in the blood plasma is 1-2.5 hours after oral administration and 6.5 hours for slow release forms. The maximum bioavailability of 30 mg tablets approaches 79%.

Distribution

The distribution of ambroxol hydrochloride from the blood into the tissues occurs quickly and clearly, with the highest concentration active substance found in the lungs. The volume of distribution after oral administration is 552 l. Communication with blood plasma proteins - 90%, penetrates the blood-brain barrier, placental barrier, and is excreted in breast milk.

Metabolism andbiotransformation

Approximately 30% of the oral dose is eliminated through first-pass metabolism. Ambroxol is initially metabolized in the liver by conjugation to form dibromanthranilic acid (approximately 10% of the dose), glucuronic conjugates and several minor metabolites.

Studies of human liver microsomes have shown that CYP3A4 is the predominant isoform responsible for the metabolism of ambroxol. After a three-day oral administration of ambroxol, approximately 6% of the dose is in free form and 26% of the dose is converted into a conjugated form and excreted in the urine.

Removal

The half-life is 10 hours. Total clearance is in the range of 660 ml/min, renal clearance accounts for approximately 83% of the total clearance.

PharmacokineticsV special groups patients

Due to the fact that the drug is metabolized in the liver and excreted by the kidneys, in cases of severe renal impairment, accumulation of ambroxol metabolites produced in the liver may occur. In patients with impaired liver function, the excretion of ambroxol hydrochloride is reduced, which leads to an increase in its level in the blood plasma by 1.3-2 times. Due to the broad therapeutic effect of ambroxol, no dose adjustment is required.

Studies have shown that the pharmacokinetics of ambroxol does not depend on age and gender and thus does not require dose changes.

Food intake does not affect the bioavailability of ambroxol hydrochloride.

Preclinical safety data

Ambroxol hydrochloride has a very low acute toxicity rate.

In multiple oral dose trials of 150 mg/kg/day (mice - 4 weeks), 50 mg/kg/day (rats - 52 and 78 weeks), 40 mg/kg/day (rabbits - 26 weeks) and 10 mg /kg/day (dogs - 52 weeks) corresponded to the maximum doses not leading to the development of observed adverse reactions (NOAELs). Toxicological studies did not reveal target organ damage.

Toxicity studies conducted over four weeks at intravenous administration Ambroxol hydrochloride in rats 4, 16 and 64 mg/kg/day and dogs 45, 90 and 120 mg/kg/day (infusion 3 h/day) did not show severe local and systemic toxicity, including histopathology. All adverse reactions were reversible.

Ambroxol hydrochloride, when tested at oral doses of up to 3000 mg/kg/day in rats and up to 200 mg/kg/day in rabbits, showed neither embryotoxic nor teratogenic properties. The fertility of male and female rats did not change when the drug was administered in doses up to 500 mg/kg/day. The NOAEL value during perinatal and postnatal development was 50 mg/kg/day. At a dose of 500 mg/kg/day, ambroxol hydrochloride exhibited slight toxicity to females and newborn offspring, resulting in delayed body weight gain and reduced offspring size. Genotoxic studies in vitro (Ames test and chromosomal aberration analysis) and in vivo (micronuclear test in mice) did not show the mutagenic potential of ambercosol hydrochloride.

Ambroxol hydrochloride did not show tumorigenic potential in carcinogenicity studies in mice (50, 200 and 800 mg/kg/day) and rats (65, 250 and 1000 mg/kg/day), when administered in mixture with food for 105 and 116 weeks, respectively.

Indications for use

Reducing viscosity and facilitating mucus discharge during colds and flu in adults/children over two years of age.

Directions for use and doses

Syrup 15 mg/5 ml

Children 6-12 years old: 5 ml (15 mg ambroxol hydrochloride) 2-3 times a day. Maximum dose 45 mg ambroxol hydrochloride per day. After 2-3 days, if the patient feels better, LAZOLVAN can be taken 2 times a day, i.e. every 12 hours.

Children 2-5 years: 2.5 ml (7.5 mg ambroxol hydrochloride) 3 times a day (every 8 hours). The maximum dose is 22.5 mg ambroxol hydrochloride per day. After 2-3 days, if the patient feels better, LAZOLVAN can be taken 2 times a day, i.e. every 12 hours.

Syrup 30 mg/5 ml

Adults: 10 ml (60 mg ambroxol hydrochloride) 2 times a day (every 12 hours). The maximum dose is 120 mg ambroxol hydrochloride per day.

If the patient feels better, the dose of LAZOLVAN can be halved.

Children over 12 years of age: 5-7.5 ml (30-45 mg ambroxol hydrochloride) 2 times a day (every 12 hours). The maximum dose is 60-90 mg ambroxol hydrochloride per day.

Children 6-12 years old: 2.5 ml (15 mg ambroxol hydrochloride) 2-3 times a day. The maximum dose is 45 mg ambroxol hydrochloride per day. After 2-3 days, if the patient feels better, LAZOLVAN can be taken 2 times a day, i.e. every 12 hours.

Children 2-5 years: 1.25 ml (7.5 mg ambroxol hydrochloride) 3 times a day (every 8 hours). The maximum dose is 22.5 mg ambroxol hydrochloride per day. After 2-3 days, if the patient feels better, LAZOLVAN can be taken 2 times a day, i.e. every 12 hours.

Children under 2 years of age: This medicine is contraindicated for children under 2 years of age.

Patients with impaired renal and liver function

Patients with impaired renal function or severely impaired liver function should take the drug only as prescribed by a doctor and under the supervision of a doctor. Since the drug is metabolized in the liver and excreted by the kidneys, in case of severe renal failure accumulation of ambroxol metabolites produced in the liver is expected.

Skipping a drug dose

If you forget to take LAZOLVAN or take an insufficient amount, continue taking the medicine according to the dosage regimen. Do not double the dose to make up for a missed dose.

If symptoms do not improve or worsen after 5 days of treatment, you should consult a doctor to reassess the clinical situation.

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Side effect

Criteria for assessing the frequency of adverse reactions medicine classified according to the international dictionary of adverse reactions, divided into system-organ classes (MedDRA system): very often (≥1/10); often (≥1/100,<1/10); нечасто (≥1/1000, <1/100); редко (≥1/10000, <1/1000); очень редко (<1/10000); частота неизвестна (невозможно определить на основании имеющихся данных).

Frequent adverse reactions are: perversion of taste, pharyngeal hypoesthesia, nausea, oral hypoesthesia.

Immune system disorders: rarely: hypersensitivity reactions; frequency unknown: anaphylactic reactions, including anaphylactic shock, angioedema, itching.

Nervous system disorders:often: perversion of taste.

Disorders of the respiratory system, chest and mediastinal organs: often: pharyngeal hypoesthesia; very rarely: rhinorrhea; frequency unknown: shortness of breath (as a symptom of an allergic reaction).

Gastrointestinal disorders: often: nausea, oral hypoesthesia; uncommon: vomiting, diarrhea, dyspepsia, abdominal pain, dry mouth; rarely: dry throat; very rarely: constipation, hypersalivation.

Disorders of the skin and subcutaneous tissues: rarely: rash, urticaria; frequency unknown: severe skin reactions (including erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis).

Cosides of the kidneys and urinary tract:very rarely: dysuria.

General disorders and reactions at the injection site: uncommon: fever, mucosal reactions.

Reporting Adverse Reactions

It is important to report suspected adverse reactions after registration of a medicinal product to ensure continuous monitoring of the benefit-risk ratio of the medicinal product. Health care professionals are encouraged to report any suspected adverse drug reactions through national adverse reaction and drug failure reporting systems.

The patient, if he experiences any undesirable reactions, is advised to consult a doctor. This recommendation applies to any possible adverse reactions, including those not listed in the instructions for use of the drug. You can also report adverse reactions to the Adverse Drug Events Information Database, including reports of drug failure. By reporting side effects, you can help provide more information about the safety of the drug.

Contraindications Hypersensitivity to ambroxol or other components of the drug. Rare hereditary intolerance to any component of the drug (see section “Precautions”). Children under 2 years of age.

Overdose No symptoms of overdose have been described in humans. In accidental overdoses and/or cases of medical malpractice, the observed symptoms have been reported to be consistent with known side effects of LAZOLVAN when used at recommended doses. Possible: nausea, vomiting, diarrhea, dyspepsia. Treatment: artificial vomiting, gastric lavage in the first 1-2 hours after taking the drug, symptomatic therapy.

Precautions There have been reports of the development of severe skin reactions, such as erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis in patients taking ambroxol.

You should immediately stop using the drug if symptoms of a progressive skin reaction (sometimes associated with the development of blisters and damage to the mucous membranes) appear and consult a doctor.

In case of impaired renal function or severe impairment of liver function, LAZOLVAN should be taken only after consultation with a doctor. Due to the fact that the drug is metabolized in the liver and excreted by the kidneys, in cases of severe renal impairment, accumulation of ambroxol metabolites produced in the liver may occur.

Patients with impaired bronchial motility and copious bronchial secretions (as, for example, with the rare syndrome of primary ciliary dyskinesia) LAZOLVAN should be used with caution due to the risk of difficulty with the discharge of large amounts of sputum and blockage of the bronchi.

Lazolvan syrup contains sorbitol (E-420). Sorbitol is a source of fructose. Patients with hereditary fructose intolerance should not use this drug.

Additive effects should be taken into account when sorbitol or fructose from other sources is used. The sorbitol content of medicinal products may affect the bioavailability of other medicinal products used simultaneously. Sorbitol may cause gastrointestinal discomfort and a mild laxative effect.

When prescribing to children aged 2 to 6 years, the risk/benefit ratio should be taken into account.

LAZOLVAN syrup 30 mg/5 ml: 1.2 g of sorbitol is contained in 5 ml of syrup, which is 4.9 g of sorbitol in the maximum recommended daily dose (20 ml).

LAZOLVAN syrup 15 mg/5 ml: 1.2 g of sorbitol is contained in 5 ml of syrup, which is 7.4 g of sorbitol in the maximum recommended daily dose (30 ml).

Pregnancy, breastfeeding and fertility Pregnancy Ambroxol hydrochloride penetrates the placental barrier. Animal studies have not revealed direct or indirect negative effects on pregnancy, embryonic/fetal development, childbirth or postnatal development. Extensive clinical experience with the use of the drug in periods later than the 28th week of pregnancy has not revealed any evidence of a negative effect on the fetus. However, it is advisable to observe the usual precautions regarding the use of any medicinal product during pregnancy. The use of LAZOLVAN is not recommended, especially during the first trimester of pregnancy.

Breastfeeding period

Ambroxol has been shown in animal studies to be excreted in breast milk. Use during breastfeeding is not recommended.

Fertility

Animal studies have not shown any direct or indirect negative effects on fertility.

Effect of the drug on the ability to drive vehicles and operate machinery

There are no known cases of the drug influencing the ability to drive vehicles and machines. No relevant studies have been conducted.

Interaction with other drugs Combined use with antitussive drugs leads to difficulty in sputum discharge while reducing cough, so caution is recommended after a careful assessment of the benefit/risk ratio. Increases the penetration and concentration in bronchial secretions of amoxicillin, cefuroxime and erythromycin. The clinical significance of this has not been established.

Packaging Syrup 15 mg/5 ml in a dark glass bottle of 100 ml, closed from the inside with plastic film and a plastic cap with first opening control, placed in a cardboard box with a measuring cup and instructions for use. Syrup 30 mg/5 ml in a dark glass bottle of 100 ml, closed from the inside with plastic film and a plastic cap with first opening control, placed in a cardboard box with a measuring cup and instructions for use.

Storage conditions Store syrup 15 mg/5 ml at a temperature not exceeding 30°C, do not freeze. Syrup 30 mg/5 ml store at a temperature not exceeding 30°C, do not freeze. Keep out of the reach of children.

The drug is suitable for the treatment of adults and children. Before you start using the medicine, it is recommended to consult your doctor.

Compound

The active ingredient of Lazolvan is ambroxol hydrochloride.

Quantitative content of the active substance for each dosage form:

  • Syrup – 30 mg per 5 ml of the drug, children’s syrup – 15 mg per 5 ml.
  • Lazolvan solution for oral administration and inhalation contains 7.5 mg of active substance per 1 ml.
  • Tablets – 30 mg per 1 piece.
  • Lozenges – 15 mg per piece.

The active ingredient of the nasal spray is tramazoline hydrochloride.

Dosage forms

A wide selection of dosage forms of the drug allows you to find a suitable remedy for all categories of patients:

  • Lazolvan nasal spray is prescribed for therapy. The drug is a clear, pale yellow liquid with a characteristic odor of eucalyptus.
  • Lazolvan solution for oral administration and inhalation is a clear, colorless or slightly brown liquid. During inhalations with Lazolvan and saline solution, the dosage and duration of the course of therapy are selected individually.
  • The syrup is a viscous, transparent, colorless liquid that has a characteristic strawberry smell. Lazolvan syrup is not used for inhalation. The dosage form is intended for internal use.
  • Tablets for internal use.
  • Lozenges for resorption.

Indications and contraindications

An inhalation solution for children and adults is prescribed as part of complex therapy for the following diseases:

  • Pathologies of the upper respiratory tract in acute and chronic form, accompanied by increased secretion of sputum.
  • (acute and chronic form).
  • Pneumonia.
  • Chronic obstructive pulmonary disease.
  • Bronchial asthma, in which the process of sputum discharge is difficult.
  • Bronchiectasis.

Inhalations with Lazolvan during pregnancy should not be carried out in the 1st trimester. Another contraindication is intolerance to the active or excipients of the drug.

Instructions and dosage

Rules for taking the drug depend on the form of release.

Lazolvan Rino

Nasal drops Lazolvan are used to eliminate:

  • swelling and nasal mucosa caused by acute respiratory infections or;
  • and middle - in order to facilitate the outflow of the contents of the paranasal sinuses.

Instructions for using Lazolvan nasal drops indicate that adults and children over 6 years of age are recommended to take up to 4 injections of the product into each nostril over 24 hours. Duration of treatment – ​​up to 7 days.

Lazolvan Rino should not be used for patients under 6 years of age, with intolerance to the components of the drug, angle-closure glaucoma, atrophic glaucoma, or a history of surgical operations on the cranial area, which were performed through the nasal cavity.

Syrup Lazolvan

Lazolvan children's syrup (15 mg/5 ml) must be taken in accordance with the dosage regimen specified by the manufacturer:

  • Children under 2 years old - 0.5 teaspoon twice a day.
  • 2-6 years - 0.5 teaspoon three times a day.
  • 6-12 years - 1 teaspoon up to 3 times a day.

The dosage regimen for adults and children over 12 years of age is 1 teaspoon of Lazolvan syrup for adults (30 mg/5 ml) three times a day. It is recommended to take this form of the drug during meals with water. The duration of treatment is no more than 5 days.

Lazolvan for inhalation

Lazolvan inhalation solution enhances the outflow and transport of mucus and helps relieve cough. During the treatment of patients with a history of chronic obstructive pulmonary disease, long-term use of Lazolvan significantly reduces the number of exacerbations. The instructions for Lazolvan for inhalation indicate that the drug can be used not only for inhalation, but also for oral administration.

The solution contains benzalkonium chloride, which can provoke the development of bronchospasms in patients with increased reactivity of the respiratory system.

Parents need to check with their doctor about how to dilute Lazolvan for inhalation for children. As a rule, a child under 6 years of age is recommended to take 1-2 inhalations with 2 ml of the drug per day.

When carrying out inhalation with Lazolvan and saline solution, the dosage for adults is 2-3 ml of the medicine up to 3 times a day. More details on how to carry out this procedure will be discussed below.

Lazolvan solution should not be mixed with alkaline solutions and products based on cromoglycic acid. Combination with antitussive drugs that make it difficult to remove sputum is also undesirable.

The instructions for use of Lazolvan for inhalation give the following recommendations regarding dosage for internal administration of the drug:

  • For children under 2 years old, give 1 ml of the product twice a day.
  • Children from 2 to 6 years old - 1 ml three times a day.
  • Children 6-12 years old - 2 ml three times a day.
  • The dosage of Lazolvan for inhalation for children over 12 years of age and adults is 4 ml three times a day.

For oral administration, the drug should be diluted in liquid: water, milk, juice, tea.

Inhalations with saline solution

A pure solution of the drug is not suitable for inhalation. It is important to know how to dilute Lazolvan for inhalation with saline solution. As a rule, they are mixed in a 1:1 ratio. This concentration of active components helps accelerate the process of liquefaction and removal of sputum.

The use of a solution for inhalation helps to increase the penetration of antibacterial substances into the bronchial mucus: amoxicillin, erythromycin, cefuroxime.

A table on inhalations with Lazolvan and saline solution, indicating the proportion, frequency and duration of the procedures, will help you avoid mistakes.

Inhalations of Lazolvan and saline solution should not be carried out using steam inhalers. If after 4-5 days there is no expected therapeutic effect, a second consultation with the attending physician is required.

How to do inhalations correctly

It is important to know how to inhale with Lazolvan. To carry out the procedure, it is necessary to use any modern equipment designed for inhalation, for example, devices that promote the spraying of drugs in the form of tiny particles.

Before using the inhaler, you should assemble it correctly and study the instructions for use, care and storage.

During the procedure, you must adhere to the following recommendations:

  • During inhalation, the patient is recommended to be in a sitting position. Carrying out inhalations in a supine position is possible only with the use of mesh nebulizers.
  • Inhalations should be carried out 90 minutes after meals or physical activity.
  • The aerosol is inhaled through the mouth through a specially designed nozzle: this allows you to accelerate the achievement of therapeutic effects. After inhaling, it is recommended to hold your breath for a few seconds and exhale through your nose.
  • During the procedure, inhaling too deeply can provoke a severe coughing attack, so you need to breathe evenly during inhalation.
  • When treating bronchial asthma, inhalation should be carried out after using medications with bronchodilator action. This helps prevent spasm and irritation of the airways.
  • The recommended temperature of the finished mixture should be approximately equal to human body temperature. This helps prevent the development of irritation in the respiratory tract.
  • Children wear a special mask during inhalation; adults use a mouthpiece that prevents the accumulation of medicine in the nasal cavity. The mask must first be wiped with hydrogen peroxide or a special disinfectant. You can't boil it.
  • The procedure should not be performed before bedtime, since the drug stimulates the secretion and removal of mucus, which can cause a severe cough.
  • You cannot use steam inhalers when performing inhalations with Lazolvan solution.

Patients with pulmonary hemorrhage, arrhythmia and severe dysfunction of the cardiovascular system should refrain from inhalation.

Side effects

Cough inhalation with Lazolvan can most often provoke the development of the following undesirable side reactions:

  • Nausea, loss of sensitivity in the oral cavity.
  • Allergic reactions.
  • Impaired sense of taste.

It is also possible to develop dyspeptic disorders, vomiting, stool disorders, abdominal pain, dry mouth and throat, skin rash, hives, swelling, itching.

Adverse reactions are mild, transient, and in most cases do not require discontinuation of use of the medication.

In case of overdose, nausea, dyspeptic disorders, abdominal pain, and bowel disorders may develop. In this case, it is necessary to induce artificial vomiting, rinse the stomach and consult a doctor for symptomatic treatment.

Analogue of the drug

A frequently prescribed analogue of Lazolvan for inhalation is Ambrobene.

This is a mucolytic agent that simultaneously has a secretomotor, secretolytic and expectorant effect. The active ingredient is ambroxol hydrochloride. The solution for inhalation is available in dark glass bottles of 40 and 100 mg.

Ambrobene is prescribed for pneumonia, bronchitis, obstructive pulmonary disease, in particular for bronchial asthma. It can even be used to treat newborns.

The question often arises, which is better for inhalations: Lazolvan or Ambrobene? The choice of drug is left to the doctor and the patient. It should be remembered that these drugs are analogues, the quantitative content of the active component in them is identical.

Inhalations with Lazolvan for dry cough may not provide the desired therapeutic result. In this case, drugs should be used that reduce the viscosity of mucus and eliminate the inflammatory process (Berotek, Berodual, Salgima). The selection of medicine is carried out taking into account the root cause that provoked the cough.

Useful video about inhalations

Lazolvan is a mucolytic drug that is used for inflammatory processes in the respiratory tract. The active substance of this medicine is ambroxol hydrochloride. This is an expectorant that helps remove excess mucus from the lumen of the bronchi. Lazolvan helps against bronchitis, pneumonia, chronic pulmonary obstruction, bronchial asthma, etc. In view of this, it is clear that the drug helps against cough. Many patients are interested in what type of cough Lazolvan is used for: dry or wet. The peculiarity of this drug is that it is effective for both manifestations of the symptom.

This medicine is available in tablets, syrup and ampoules, as it is used to treat both adults and children. In addition, there are also lozenges for children.

Indications for use

Lazolvan is prescribed for the treatment of dry and wet cough. But if this symptom is caused by such pathological conditions:

  • Bronchitis with acute and chronic course. This is an inflammation of the mucous membranes of the bronchial passages. In this case, there may be a characteristic symptom - yellow or green sputum. This means that the cause of the pathology is a bacterial infection. Lazolvan is effective in this case.
  • Pneumonia, that is, inflammation of the lungs. This disease is provoked by bacterial microorganisms or fungi, so to treat cough you will need Lazolvan in combination with antibiotics.
  • Chronic obstructive pulmonary disease. This pathology is bronchitis in combination with emphysema.
  • Bronchial asthma. This is a chronic disease in which attacks of suffocation accompany a person regularly. If the cough is accompanied by the removal of sputum, then Lazolvan is an effective remedy.
  • Bronchiectasis. In this case, the bronchi expand and become deformed. This pathology is accompanied by a cough with the release of purulent sputum, and there may also be a high temperature. In this case, Lazolvan quickly removes mucus along with bacteria.
  • Respiratory distress syndrome. This pathology occurs in premature babies.. In order for the lungs to function normally, the child is given a drug that activates the production of surfactant. Lazolvan is one of such medicines.

Effect of the drug

Is Lazolvan an antibiotic or not? This question comes up often. The answer is clear - no, it is mucolytic. Therefore, its action is aimed at diluting sputum, which, due to its viscosity, is difficult to remove from the lungs. Under the influence of Lazolvan, a surfactant is produced, that is, a substance that allows you to quickly remove sputum along with pathological bacteria by coughing. At the same time, recovery occurs faster.

The bronchi contain microscopic hairs that are designed to move mucus. The active substance of the drug activates the functioning of these hairs.

Lazolvan is effective as part of combination therapy. Namely, together with antibacterial drugs. This treatment is prescribed for advanced pneumonia, accompanied by a chronic cough. In this case, Lazolvan promotes the production of pulmonary secretions. Quite often, when combining this drug with an antibiotic, the doctor prescribes a smaller dose of the antibacterial agent. This is especially important in treating children.

Lazolvan is not aimed at blocking the cough process. This is very important in the treatment of inflammation in the upper and lower respiratory tract. Since for the best effect it is necessary to remove the contents of bronchial mucus.

When to take Lazolvan - for dry or wet cough? This medicine will help with both types of cough.. With a dry cough, the mucus liquefies and the process of its removal begins, and with a wet cough, it accumulates in the lumens of the respiratory tract faster and is removed more efficiently.

Lazolvan for dry cough

A dry cough is an extremely unpleasant symptom that makes breathing difficult. In this case, the drug thins the mucus that has settled in the bronchi. At this stage, the sputum is very thick and it is difficult for the bronchi to remove it on its own. Therefore, a dry, unproductive cough occurs. The drug helps to increase the amount of mucus, since only after this the expectoration will be more productive. Therefore, Lazolvan worsens cough.

For dry coughs in children and adults, Lazolvan dilutes sputum, as a result, a person’s breathing significantly improves. But it is important to understand that the cough will only get worse and will begin to turn into a wet one.

It is important to note that dry cough can be caused by tracheitis, laryngitis, pharyngitis, and tonsillitis. Coughing in these pathologies makes breathing difficult and the person suffers from paroxysmal suffocation and discomfort in the throat. Such symptoms often lead a person even to psycho-emotional disorders. In cases where the larynx is affected, Lazolvan is not recommended for use in dry coughs in adults and children, as it can provoke spasms of the larynx. Doctors do not prescribe this drug for such pathologies, since there is no wheezing in the bronchi.

To make the process of sputum removal from the bronchi faster, you should take Lazolvan for a wet cough. This medicine will help completely cleanse the lungs and bronchi. Consequently, the inflammation goes away, but only if it is not provoked by a bacterium.

Lazolvan is effective in the form of inhalations for a wet cough in a child. Since the active substance penetrates directly deep into the respiratory tract.

When a wet cough occurs due to pneumonia, the use of Lazolvan is also very effective. Only the dosage is set by the doctor depending on whether the cough is productive or unproductive.

Release form

Lazolvan is available in a variety of pharmacological forms, since it is recommended for children of all ages and adults to take it. All recommendations are indicated in the instructions for the drug.

Pills

Lazolvan is available in tablet form. This is the form of the drug that is recommended for use by adults and children over 12 years of age.. This age group is usually prescribed 1 tablet 3 times a day. This regimen lasts from 1 to 3 days, and then the dose is reduced to 2 times a day, and children can be prescribed 0.5 tablets.

Sometimes doctors prescribe cough tablets for children over 6 years of age. In this case, a single dose is 0.5 tablets, you need to drink them 3 times a day. And then the dose is reduced. The tablets should be taken during meals, and washed down with a small amount of water.

If the disease of the respiratory system has become severe, then it is not recommended to reduce the dosage throughout the entire course of treatment.

Syrup


For children, Lazolvan syrup is better than tablets
. It is usually prescribed to patients over 6 years old, half a measuring spoon, which is included with the drug. But according to the instructions for use of the syrup, Lazolvan for dry cough in adults and children over 12 years of age can also be used in this pharmacological form. But the dosage is much higher - 1 tbsp. l. at a time.

After the syrup enters the gastrointestinal tract, it begins to act within 15 minutes, and the therapeutic effect lasts for 6-12 hours.

According to the instructions, Lazolvan for children in the form of syrup is not recommended for patients under 6 years of age, but sometimes doctors prescribe it, only the dosage is adjusted depending on the age of the child. In this case, children 2-6 years old are recommended to take 2.5 ml of syrup 3 times a day. And for children under 2 years of age, the same dose is only 2 times a day. Such treatment should be carried out under the supervision of a physician.

Lazolvan syrup contains fructose, which may cause an allergic reaction.. It is also not recommended to give it to children who have dermatitis and other rashes on the body or mucous membranes.

Ampoules


Lazolvan, which is available as a liquid substance in ampoules, is indicated for intramuscular, intravenous or subcutaneous administration
. Most often, this form of the drug is prescribed to adult patients. The single dose is 15 ml. But in severe cases it increases to 30 ml, that is, 2 ampoules at a time.

As for children, the dosage is prescribed based on weight. The proportion is 1.6 ml per kg of weight. But there are cases when the dose is increased on the first day of treatment.

Inhalations

Inhalations with Lazolvan are recommended for both adults and children. They need to be used for 2-3 sessions daily, if one procedure involves 2-3 ml of the substance. Typically, children over 12 years of age and adults need inhalation with a solution containing 4 ml of Lazolvan. For children over 6 years of age, the dose of the drug at a time should not be more than 2 ml, do it 3 times a day.

Sometimes inhalations are prescribed for children over one year of age, but with a severe cough. In this case, the dose of Lazolvan used is prescribed only by a doctor. For children under 2 years of age, it is recommended to use a solution with 1 ml of the active substance at a time, the procedure should be carried out 2 times a day. And at the age of 2 to 6 years, the dosage is the same, only the frequency of administration changes - 3 times a day.

The maximum effect after inhalation is achieved after 3 hours. In this case, the active substance penetrates deep into the bronchi, spreading throughout the respiratory tract. But still, most of all, the active substance is localized in the lungs. The therapeutic effect lasts 7-12 hours.

An important indicator is also the time of one procedure:

  • For children under 6 years of age, this time should be no more than 3 minutes.
  • For children over 6 years old, the time of one inhalation should not exceed 5 minutes.
  • For adults, the procedure should last 5-6 minutes.

Inhalations with Lazolvan are effective for obstructive chronic pulmonary pathologies. In this case, long-term procedures are prescribed. This treatment will help significantly delay the next exacerbation of the disease.

Patients with increased reactivity of the respiratory system should carefully use such inhalations, since liquid Lazolvan contains the substance benzalkonium chloride. And this means that after inhalation, bronchospasm may occur, which will aggravate the patient’s condition.

To prepare a solution for inhalation, it is important to know some rules. You cannot combine Lazolvan with alkaline solutions and solutions based on cromoglycic acid. Another dangerous combination is Lazolvan and antitussive drugs. Such solutions will provoke spasms and make it difficult to remove mucus from the bronchi.

The inhalation solution for dry and wet cough can be taken orally. To do this, you will need to dilute the prescribed dose in liquid and drink. This could be milk, tea, juice, etc.

Lazolvan and bronchitis


Chronic bronchitis is a pathology that causes a dry cough
. And exacerbations of this pathology occur in a fairly severe form. Clinical studies have shown that Lazolvan for cough for children and adults gives a positive result when included in treatment therapy. Since the active substance of the drug penetrates the mucus composition, due to this, the bronchi are released. In addition, bronchitis provokes a dry cough, which causes pain. Lazolvan removes these sensations, which means the patient’s condition is significantly alleviated.

In the chronic type of bronchitis, as a result of frequent inflammation, the bronchi become clogged, the lumen narrows and their deformation occurs. At the same time, the medicine also effectively clears the lumen of the bronchi from mucus.

Lazolvan for bronchitis in children and adults has a local immunomodulatory effect, since during the treatment process antibodies are formed in the sputum, which stimulate immune cells.

Contraindications


Before prescribing Lazolvan, any doctor will make sure that the patient does not have renal or liver failure, and it is also not recommended to take the medicine during the first trimester of pregnancy and lactation
.

It is better for nursing women not to take the tablet form of Lazolvan; in this case, it is preferable to take it intramuscularly or intravenously.

If a person takes the drug in excess of the prescribed dosage, then characteristic symptoms of an overdose may appear:

  • attacks of nausea and vomiting;
  • diarrhea;
  • flatulence;
  • abdominal pain.

Overdose occurs extremely rarely. This condition is especially dangerous for children.

Lazolvan during pregnancy

During pregnancy, a woman's immunity decreases, so quite often during this period she can become infected with various viral infections. A severe cough has an extremely negative impact on the condition of the child and the pregnant woman.. Therefore, it is necessary to urgently begin treatment. Quite often, doctors prescribe Lazolvan to women during the second trimester of pregnancy. Inhalations or tablets are effective.

This prescription is made only by a doctor, and the doctor also sets the dosage. If you follow the doctor's instructions, there will be no negative effects. The course of treatment should not exceed 10-14 days.

If, when taking Lazolvan, a dry cough intensifies, itching and redness of the skin appear, then it is necessary to stop taking it. You should also consult your doctor for advice.

Treatment results

The results of therapeutic therapy with Lazolvan are often positive, since, according to statistics, side effects are extremely rare. When using this drug, after the first dose, the breathing process is facilitated; if a person has pain in the larynx, then Lazolvan relieves them. Sputum is removed qualitatively, and as a result, recovery occurs without complications.

Of course, during use, negative results in the form of side effects may also occur. But this rarely happens.

Cough accompanies most respiratory diseases. Treatment of the clinical syndrome, depending on its type, requires the use of a number of medications that reduce the frequency of coughing attacks. Such drugs include Lazolvan, the instructions for use of which contain an approximate dosage regimen. It also spells out possible restrictions on admission.

Few people know what kind of cough Lazolvan will help with. The mucolytic acts comprehensively, eliminating unproductive coughing and evacuating mucus from the bronchi. The drug has high bioavailability; the manufacturer provides various forms of release, including a solution for inhalation.

Description of the drug

Lazolvan for cough can be used by pregnant women, children and adult patients. Syrup and tablet (including lozenges) forms of release may have age restrictions.

Release form

Several forms of the drug allow patients to choose the most convenient cough treatment option. The solution is transparent, brown in color. Lazolvan tablets are white (less often yellow), round, flat. The edges of the dosage form are beveled and the company logo is engraved. Chamfer and risk are present.

Lazolvan syrup is transparent, with a berry (strawberry) aroma and a sweetish taste. The lozenges are round, flat, brown in color with a mint smell. The solution and Lazolvan for children are sold in glass bottles of various volumes (100–200 ml), tablets are sold in thin plastic blisters.

Composition and beneficial properties of Lazolvan for cough

The manufacturer provides active additives in the composition of the product. The main component is ambroxol (in the form of hydrochloride). Its concentration may vary (7.5–15–30 mg). Depending on the form of release, Lazolvan contains the following additional elements:

  1. In solution - carboxylic acid (tribasic), alkylbenzyldimethylammonium chloride, sodium hydrogen phosphate (dihydrate), distilled water.
  2. The pills contain starch of plant origin (corn), magnesium salt of stearic acids, lactose, silicon dioxide.
  3. Lozenges contain sorbitol, gum, eucalyptus oil, essential peppermint oil, sweetener (saccharin), paraffin, purified water.
  4. The syrup contains benzoic acid, flavors identical to natural, sorbitol, glycerol, potassium salt, purified water.

The lowest concentration of the main component (ambroxol) is present in the Lazolvan solution. In pills - no more than 30 mg of the active element, in syrup and lozenges - 15 mg. The expectorant and mucolytic effect of Lazolvan is due to its composition.


Eucalyptus oil is one of the components of Lazolvan lozenges

Use of Lazolvan in children

Lazolvan is not recommended for children under one year of age. Children from 2 years old are given only syrup. Cough medicine for children is taken depending on the prescribed dose. The therapeutic norm is determined by a specialist depending on the severity of the disease and the frequency of coughing attacks.

Use of Lazolvan during pregnancy and breastfeeding

When breastfeeding, it is strictly forbidden to use Lazolvan, regardless of the release form. The active component passes into breast milk and overcomes the placental barrier, so the medication is not used in the first 3 months of pregnancy. From the second trimester, mucolytics can be treated if there is no threat to the life of the fetus or woman. Reception should be carried out under the supervision of a doctor and according to the instructions.

Indications for use

The instructions for use contain the following indications:

  • bronchitis without cough;
  • chronic bronchitis (in the acute stage);
  • respiratory viral infections;
  • pulmonary obstruction;
  • respiratory distress syndrome;
  • pneumonia;
  • bronchial asthma.

According to the instructions, Lazolvan can be used for diseases accompanied by a severe cough.


Cough with chronic bronchitis

For what type of cough is it used?

Many people are interested in what kind of cough Lazolvan can be used for. Dosage forms of the drug are used according to the instructions for 2 types of cough: wet and unproductive.

Lazolvan for wet cough

With a wet cough, Lazolvan expands the lumens of the bronchi and accelerates the removal of exudate. The medicine acts gently, reducing the frequency of coughing attacks. Treatment of the clinical syndrome accompanying the disease can be carried out using any form of release. Lazolvan also relieves inflammatory processes in the respiratory system for wet coughs.

According to the World Health Organization, a wet cough is observed in every 2nd patient. Every year, attacks of wet cough with sputum discharge occur in every 3rd child. Children under 6 years of age get sick more often than adults, especially in winter.

Lazolvan for dry cough

For dry cough, do not take Lazolvan syrup, tablets and lozenges. The solution is used for medicinal purposes. Inhalations with Lazolvan for dry cough are carried out according to the instructions. Particles of the active component, together with steam, penetrate the respiratory tract faster.


A man makes inhalation with Lazolvan

Contraindications and side effects

Any form of release goes on sale along with instructions for use, which are enclosed in a cardboard box. The medicine has a number of contraindications, in the presence of which it is impossible to take it. These include:

  • period of bearing a child (first trimester);
  • breastfeeding period;
  • individual intolerance to active or auxiliary elements).

The medication also has relative limitations. These include liver and kidney failure. Independently increasing the therapeutic dose increases the risk of developing a number of side effects.

Most often, they arise from the digestive tract. These include stomach and intestinal disorders, including impaired bowel movements, constipation or diarrhea, heartburn and dyspepsia.

Side effects from taking Lazolvan include allergic reactions. They occur against the background of a slight excess of the daily norm. Most often, this is hyperemia, redness and peeling of the skin, burning and itching.


The period of breastfeeding is the main contraindication to the use of Lazolvan

Instructions for use

Instructions for use of Lazolvan involve oral administration of most dosage forms. The dosage regimen is determined individually. The therapeutic norm is prescribed by a specialist based on the severity of the disease and the intensity of its manifestation. In case of a severe cough attack, with the permission of the attending physician, the dose may be increased. For each individual dosage form there is a specific method of administration.

Mode of application

Inhalations with Lazolvan must be carried out according to the instructions. Drops (solution) are mixed in equal parts with sodium chloride. The resulting mixture is poured into a nebulizer. Steam inhalers cannot be used for these purposes. The solution heated to room temperature is inhaled slowly - a sharp inhalation can provoke a severe coughing attack.

Lazolvan tablets are taken whole; chewing them is not recommended. You don’t have to take the baby syrup with water; it tastes good.

Dosage

An approximate dosage regimen is prescribed in the instructions for use of Lazolvan. Dosage regimen (depending on release forms):

  1. Tablets - no more than 1 tablet once three times a day.
  2. Syrup -2.5-10 ml (depending on age) once. Children from 2 to 6 years old - 2.5 ml, children from 7 to 12 years old - 5 ml once, children over 12 years old - no more than 10 ml. The syrup is drunk 2-3 times a day.
  3. Lozenges - 1–2 pills 3–4 times a day or with each coughing attack.

The solution for inhalation can be taken orally. Dosage regimen: no more than 20 drops at a time.


Girl takes a pill

How to use

The tablet form must be taken with plenty of water. The syrup is taken in its pure form; it is not recommended to dilute it with water. Lozenges need to be dissolved.

Before or after meals

Any dosage form, according to the instructions, can be taken before, after or during meals.

Dry cough after Lazolvan

In rare cases, after Lazolvan the cough may get worse. This may be due to the stimulating properties of the drug; cough often appears after inhalation. Often, coughing attacks can signal the development of complications. Deterioration of the condition requires immediate contact with a specialist.

special instructions

According to the instructions, it is strictly forbidden to drink alcohol during treatment with Lazolvan. The drug does not reduce concentration, driving is allowed.

Can it be taken together with other drugs?

The medication cannot be used for medicinal purposes simultaneously with antitussive medications. Antibiotics can be included in complex therapy along with a mucolytic - in this case, the concentration of the latter in the blood increases.


Is it possible to take Lazolvan with other medications?

Analogues and cost

Lazolvan has several structural analogues and generics. These include:

  1. Ambromol. The syrupy form of release has the same composition as the original. The main indications for use are respiratory pathologies. Do not use during breastfeeding and pregnancy.
  2. Bronchorus. Sold in pill form. It has expectorant and antispasmodic properties. There are age restrictions (up to 12 years).
  3. . The closest structural analogue of the original. Available in the form of syrup with raspberry flavor and smell. Eliminates dry and wet cough.

The cost of Lazolvan in pharmacies may vary depending on the place of sale and form of release. Approximate cost - 160–190 rubles.