Nutraceuticals are used for. Nutraceuticals: what they are and what they eat them with. Distinctive features of dietary supplements of this group

Biologically active food supplements (BAA) are specially designed to help our body. At the same time, dietary supplements are not a cure for diseases or excess weight, but one of the ways to supplement the daily diet with a complex of useful and nutritious substances, most of which the body does not synthesize on its own, but can only obtain from food.

Dietary supplements are traditionally divided into nutraceuticals and parapharmaceuticals. However, at present, such a division can be considered conditional, since most products are complex drugs, that is, they act as nutraceuticals and parapharmaceuticals at the same time.

Nutraceuticals– irreplaceable (essential) nutritional components that protect the body from external and internal risk factors. These are proteins, amino acids, polyunsaturated fatty acids, phospholipids, carbohydrates, dietary fiber.

Nutraceuticals are unique in that they can be used daily for an unlimited amount of time along with the products we consume, improving their digestibility and maintaining our health at the highest level. Nutraceuticals are effective means of preventing “diseases of civilization” - diabetes, obesity, immunodeficiency states, diseases of the gastrointestinal tract and cardiovascular system, and the musculoskeletal system.

Nutraceuticals are an essential part of food, which do not require special indications for use and have no contraindications. They are used by both sick and healthy people.

Nutraceuticals Company Coral Club– Ultimate, Apricotabs, Children's delicious vitamins, Omega 3/60, Protiviti, Colostrum (FirstFoot), Selenium, Zinc, etc.

The use of nutraceuticals in the daily diet of different population groups (children, young and elderly people, athletes, people with poor health) allows:

– compensate for the lack of essential nutrients in children and adults;

– take into account in the nutrition of each individual person his individual needs, which depend not only on gender, age, but also on the genetically determined characteristics of the metabolism of an individual organism, its biorhythms, environmental living conditions, physiological conditions (emotional stress, physical activity, etc. .);

– ensure that the sick person’s need for nutritional nutrients is maximized;

– increase the body’s protective response from the effects of adverse environmental factors;

– influence enzyme systems, accelerate and enhance the removal and binding of toxins and foreign substances from the body.

Parapharmaceuticals– these are natural remedies that have a targeted physiological effect and are used to prevent various diseases. Composition of parapharmaceuticals– complexes of bioactive substances isolated from plants: glycosides, alkaloids, phenolic compounds, enzymes, organic acids, phytoncides, saponins, essential oils, terpenoids, flavonoids, tannins, etc.

The vast majority of parapharmaceuticals are safe to use. Compared to medications, they have a beneficial healing effect on the functions of individual organs and systems of the body, with a significantly lower likelihood of side and toxic effects.

In large doses, these dietary supplements are already considered medicines.

Advantages of parapharmaceuticals over drugs:

1. Obtained from medicinal or food plants of an ecological niche;

2. They contain natural water- and fat-soluble complexes of biologically active natural components;

Action parapharmacists carried out in the following areas:

– systems that participate in the development of adaptive reactions of the body are activated;

– the functional activity of individual organs and systems is regulated;

– stimulates the activity of the nervous system, physical and mental performance;

– metabolism is regulated, as well as the motor-evacuation function of the gastrointestinal tract.

Parapharmaceuticals Company Coral Club– Diosin, Ant tree bark, Cat's claw, Herbal sets, Alfalfa, Black walnut leaves, Eyebright, Echinacea, etc.

Complex products – Microhydrin, Bioshape, spirulina products, Fito-Si, Enduro-max, etc.

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Ministry of Health of the Republic of Belarus

"Vitebsk State Order of Peoples' Friendship Medical University"

Department of General and Clinical Biochemistry

Abstract on the topic:

"Parapharmaceuticals and nutraceuticals"

Prepared by:

3rd year student, 15th group

Faculty of Pharmacy

Kotovich E.V.

Checked by: Orlova L.G.

Vitebsk 2014

Introduction

Nutraceuticals

Parapharmaceuticals

Conclusion

Bibliography

Introduction

According to experts, people's health depends 12% on the level of healthcare, 18% on genetic predisposition, and 70% on lifestyle, the most important component of which is nutrition.

Medical views, while never generally stable, have been unanimous throughout human history on one thing: the poorer the diet, the more disease there is. Experts say that the human diet today should contain more than 600 different substances (nutrients). Unfortunately, not everyone can afford a balanced diet of all nutrients. This is where biologically active additives (BAA) come to the rescue - concentrates of natural substances isolated from food raw materials of animal (including marine), mineral, plant origin, or substances obtained by chemical synthesis that are identical to natural analogues.

All dietary supplements are divided into three groups:

1. Nutraceuticals

2. Parapharmaceuticals

3. Nutritional supplements

Let's look at nutraceuticals and parapharmaceuticals in more detail.

Nutraceuticals

Nutraceuticals are dietary supplements designed to replenish essential substances (essential nutritional factors) in the body. They are divided into groups:

· nutraceuticals intended for functional nutrition;

· nutraceuticals intended to replenish nutrients, the synthesis of which is weakened for some reason (intestinal dysbiosis, chronic diseases).

The criterion for determining dietary supplements for them is the recommended daily requirement for certain nutrients.

Daily requirements are recommended standards that determine the amount of a specifically important nutritional component required to prevent nutritional deficiency and related diseases. Therefore, at best, this is the lowest limit of a nutrient that will prevent nutritional deficiency and subsequent disease.

Nutraceuticals include: vitamins, coenzyme Q10, minerals, antioxidants, amino acids, essential fatty acids, chelate complexes, dietary fiber, enzymes.

All nutraceuticals can be divided into 2 groups.

The use of nutraceuticals in the daily nutrition of sick and healthy people allows:

· easily and quickly eliminate the lack of essential nutrients, which is widely detected in the majority of the adult and child population of Russia;

· take into account individual needs in the nutrition of a particular person, which differ significantly not only in age, gender, intensity of physical activity, but also due to the genetically determined characteristics of the metabolism of an individual, his biorhythms, environmental conditions of the region of residence, physiological conditions - pregnancy, psycho-emotional stress, etc. .d.;

· to ensure as much as possible the altered physiological needs for nutrients of a sick person, to bypass areas of metabolic pathways damaged by the disease, and sometimes to carry out their correction (for example, the nutrition of a patient with phenylketonuria);

· by strengthening the protection elements of cellular enzyme systems, increase the general, nonspecific resistance of the body to the effects of adverse environmental factors in the population living in both ecologically clean and environmentally unfavorable regions;

· acting primarily on enzyme systems, purposefully changing the metabolism of individual substances, in particular xenobiotics, as well as strengthening and accelerating the binding and removal of foreign and toxic substances from the body.

Thus, the use of nutraceuticals is an effective means of prevention, as well as additional (and sometimes primary) treatment of patients with widespread chronic diseases such as obesity, diabetes mellitus, cardiovascular diseases, malignant neoplasms, immunodeficiency conditions, diseases of the gastrointestinal tract , degenerative diseases of the musculoskeletal system.

Functions performed by nutraceuticals

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Parapharmaceuticals

Parapharmaceuticals (from the Latin para - about, pharmaceuticals - medicines) include medicinal plants, algae, and mushrooms. These are, as a rule, products containing minor food components: bioflavonoids, organic acids, glycosides, biogenic amines, regulatory oligopeptides, polysaccharides, oligosaccharides, etc. The action of parapharmaceuticals is implemented in the following areas:

· regulation within physiological boundaries of the functional activity of individual organs and systems;

· activation of systems involved in the development of adaptive compensatory and adaptive reactions of the body;

· regulation of the nervous system, including higher nervous activity;

· regulation of microbiocenosis of the gastrointestinal tract.

These properties of parapharmaceuticals allow the human body to adapt to changed, extreme conditions, and provide additional, auxiliary therapy for various diseases, which qualitatively expands the capabilities of basic treatment methods.

Differentiation of parapharmaceuticals from drugs occurs according to the following criteria:

· therapeutic dose. If dietary supplements present in the drug do not exceed the therapeutic dose, then it is classified as parapharmaceuticals

· expected effectiveness. When using parapharmaceuticals - after 8-12 weeks

· no side effects.

Depending on the biotechnological method of their production, parapharmaceuticals are divided into several groups:

The vast majority of parapharmaceuticals are safe to use. Although when using parapharmaceuticals, the phenomenon of individual intolerance to their individual components cannot be ruled out, which, however, is also typical for some food products and even more so for medications. Thus, parapharmaceuticals, without replacing medications, significantly improve the quality of preventive and therapeutic measures.

Functions performed by parapharmacists

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Examples of parapharmaceuticals and nutraceuticals

Vitamins are used as nutraceuticals. Vitamins are low molecular weight organic compounds of various chemical natures that are necessary for normal life and have high biological activity. In the human body, vitamins are not synthesized (or synthesized in insufficient quantities), but are supplied to it with food. Some vitamins are waste products of intestinal microflora and, when absorbed in the intestines, to some extent satisfy the body's need for these substances. Unlike other essential nutritional factors, vitamins do not serve as a source of energy or material for biosynthetic plastic processes, but perform mainly the function of regulators of numerous biochemical reactions, which together constitute metabolism and energy.

Sources of vitamins for humans are food products of plant and animal origin. Due to the fact that the normal course of various physiological and biochemical processes cannot be ensured in the absence of vitamins, insufficient intake of vitamins into the body leads to the development of pathological conditions - hypovitaminosis and vitamin deficiency.

Preparations containing vitamins are used in the winter-spring period and in all cases when the diet includes an insufficient amount of vitamins. Vitamin preparations are used as medicines. Introducing excess vitamins into the body can lead to hypervitaminosis.

Bee products are used as parapharmaceuticals. For example, bee honey contains about 300 different substances that determine its bactericidal, antiallergic and antihemorrhagic effect. Honey is widely used in the treatment of wounds and ulcers, for diseases of the liver and gallbladder, peptic ulcers of the stomach and duodenum, colitis, and chronic constipation. It improves coronary blood flow, myocardial contractility, helps lower blood pressure, and is effective in the treatment of insomnia, neuroses, some diseases of the respiratory and genitourinary systems, eyes, and skin.

Propolis has a broad pharmacological effect, which is determined by many biologically active substances it contains, including flavonoids, sterols, and vitamins. Propolis has antibacterial, anti-inflammatory, immunostimulating, local anesthetic, antifungal, and antipruritic effects. Various medicines are produced from it, including alcohol tincture and propolis oil. They are used in the treatment of long-term non-healing wounds, trophic ulcers, burns and frostbite, as well as many therapeutic diseases

Conclusion

nutraceutical parapharmaceutical supplement concentrate

In order to optimize the nutrition of a practically healthy population and people with reduced nonspecific resistance of the body, it is recommended to prescribe nutrition with the inclusion of dietary supplements that help eliminate the lack of nutritional and biologically active substances. Along with this, it is necessary to include biologically active food additives in preventive and therapeutic nutrition. Preventive nutrition with the addition of dietary supplements is aimed at correcting and eliminating risk factors for the development of diseases. And the inclusion of dietary supplements in medical nutrition serves the purpose of meeting the increased needs of the sick person’s body, helping to adapt the chemical composition and energy value of the diet to the characteristics of the pathogenetic mechanisms of the disease.

Now the time urgently requires enriching food products with the nutrients we need. One of the ways to replenish them is the regular use of vitamins, premixes, and enrichment of food products with nutrients, although this is difficult from a technological point of view. Such food additives can be vitamin-mineral mixtures, prophylactic salts (iodized, low sodium), multifunctional herbal supplements (for example, wheat germ).

Bibliography

1. Orlova S.V., Encyclopedia of dietary supplements for food, Moscow, 1998.

2. Menshikov F.K., Diet therapy, Moscow, Medicine, 1972.

3. Vasilaki A.F., Kishenko Z.V., A short guide to dietary nutrition, Chisinau, Shtinitsa, 1980.

4. Maev I.V., Petukhov A.B., Tutelyan V.A. and others. Biologically active food additives in preventive and clinical medicine. / Moscow, VUNMC 1999.

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A dietary supplement for weight loss is a mysterious remedy, it is not clear whether it is useful or harmful, how effective is it and is it worth using? One of the types of dietary supplements for weight loss are nutraceuticals. Nutraceuticals (damn what a word)) are meal replacements or simply ideal food.

Most often, a nutraceutical is a protein powder from which you can prepare a cocktail based on juice, milk, kefir or yogurt with fruits or berries. Sounds temptingly delicious.

Dietary supplements for weight loss

Why is this the perfect food? The fact is that a meal replacement contains (at least should (!) contain) high-quality protein (protein), which is necessary for complete effective weight loss. If you haven’t read about this yet, I suggest you read the article about Proteins for weight loss, Part 1 and Part 2, where we discussed in detail why protein is needed and why.

In addition, these dietary supplements include vitamins or their precursors, macro- and microelements and polyunsaturated fatty acids. Due to their composition, nutraceuticals, saturating the body with all these beneficial substances, improve its condition. Thus, giving a signal that it contains a sufficient amount of everything necessary and you can get rid of the excess immediately.

Simply put, excess weight, or rather fat, is a disease of the body, a lack of proteins, vitamins and essential substances and an excess of sugar, dyes, pesticides, fertilizers and chemicals. By giving what is necessary, we get rid of what is unnecessary.

Dietary supplements for weight loss and health

Another dietary supplement for weight loss or nutraceutical is a very valuable thing for very busy people, because you only need 1-2 minutes to prepare a full meal.

To lose weight, replace 1-2-3 meals a day and with a minimum of calories (specially calculated by the manufacturer, it is 200-250 calories) your body receives maximum nutritional value.

IMPORTANT: why not just take some vitamins, supplements, etc. Firstly, vitamins and microelements are absorbed with a sufficient amount of protein in the diet (when nutraceuticals are consumed, all this is balanced in one serving), otherwise they simply pass through the toilet. In addition, the nutraceutical contains the optimal amount of vitamins, protein and all substances in the required quantity. As a result, there is no need to independently calculate your diet and you can be sure of the optimal price-quality ratio.

Dietary supplements for weight loss

Speaking of quality. Before you start using this or that product, read reviews, certificates, and make sure the quality of the product. On my own behalf, I can add that the leading manufacturer of dietary supplements for weight loss around the world is the Herbalife company, which produces products for weight control and weight loss. Undoubtedly, a dietary supplement for weight loss - a nutraceutical - is a useful and convenient thing. But what will happen if you stop using it, will you really gain weight???

Indeed, this method of losing weight is for those who want to get excellent results in the shortest possible time, with benefits for the body, without diets and fasting. It must be remembered that after you finish using the product, you take responsibility for the quality of your diet (I’ll tell you a secret that it’s almost impossible to ensure such quality on your own, because there will be either a shortage of nutrients, or too much calories and quantity). Therefore, if funds allow, make such an investment in your health - this is a profitable investment.

A dietary supplement for weight loss is a mysterious remedy, it is not clear whether it is useful or harmful, how effective is it and is it worth using? One of the types of dietary supplements for weight loss are nutraceuticals. Nutraceuticals (damn what a word)) are meal replacements or simply ideal food.

Most often, a nutraceutical is a protein powder from which you can prepare a cocktail based on juice, milk, kefir or yogurt with fruits or berries. Sounds temptingly delicious.

Why is this the perfect food? The fact is that a meal replacement contains (at least should (!) contain) high-quality protein (protein), which is necessary for complete effective weight loss. If you haven’t read about this yet, I suggest you read the article about Proteins for weight loss, Part 1 and Part 2, where we discussed in detail why protein is needed and why.

In addition, these dietary supplements include vitamins or their precursors, macro- and microelements and polyunsaturated fatty acids. Due to their composition, nutraceuticals, saturating the body with all these beneficial substances, improve its condition. Thus, giving a signal that it contains a sufficient amount of everything necessary and you can get rid of the excess immediately.


Simply put, excess weight, or rather fat, is a disease of the body, a lack of proteins, vitamins and essential substances and an excess of sugar, dyes, pesticides, fertilizers and chemicals. By giving what is necessary, we get rid of what is unnecessary.

Another dietary supplement for weight loss or nutraceutical is a very valuable thing for very busy people, because you only need 1-2 minutes to prepare a full meal.

To lose weight, replace 1-2-3 meals a day and with a minimum of calories (specially calculated by the manufacturer, it is 200-250 calories) your body receives maximum nutritional value.

IMPORTANT: why not just take some vitamins, supplements, etc. Firstly, vitamins and microelements are absorbed with a sufficient amount of protein in the diet (when nutraceuticals are consumed, all this is balanced in one serving), otherwise they simply pass through the toilet. In addition, the nutraceutical contains the optimal amount of vitamins, protein and all substances in the required quantity. As a result, there is no need to independently calculate your diet and you can be sure of the optimal price-quality ratio.


Speaking of quality. Before you start using this or that product, read reviews, certificates, and make sure the quality of the product. On my own behalf, I can add that the leading manufacturer of dietary supplements for weight loss around the world is the Herbalife company, which produces products for weight control and weight loss. Undoubtedly, a dietary supplement for weight loss - a nutraceutical - is a useful and convenient thing. But what will happen if you stop using it, will you really gain weight???

Indeed, this method of losing weight is for those who want to get excellent results in the shortest possible time, with benefits for the body, without diets and fasting. It must be remembered that after you finish using the product, you take responsibility for the quality of your diet (I’ll tell you a secret that it’s almost impossible to ensure such quality on your own, because there will be either a shortage of nutrients, or too much calories and quantity). Therefore, if funds allow, make such an investment in your health - this is a profitable investment.

uroki-pitaniya.ru

Biologically active food supplements (BAA) are specially designed to help our body. At the same time, dietary supplements are not a cure for diseases or excess weight, but one of the ways to supplement the daily diet with a complex of useful and nutritious substances, most of which the body does not synthesize on its own, but can only obtain from food.


Dietary supplements are traditionally divided into nutraceuticals and parapharmaceuticals. However, at present, such a division can be considered conditional, since most products are complex drugs, that is, they act as nutraceuticals and parapharmaceuticals at the same time.

Nutraceuticals– irreplaceable (essential) nutritional components that protect the body from external and internal risk factors. These are proteins, amino acids, polyunsaturated fatty acids, phospholipids, carbohydrates, dietary fiber.

Nutraceuticals are unique in that they can be used daily for an unlimited amount of time along with the products we consume, improving their digestibility and maintaining our health at the highest level. Nutraceuticals are effective means of preventing “diseases of civilization” - diabetes, obesity, immunodeficiency states, diseases of the gastrointestinal tract and cardiovascular system, and the musculoskeletal system.


Nutraceuticals are an essential part of food, which do not require special indications for use and have no contraindications. They are used by both sick and healthy people.

Nutraceuticals Company Coral Club– Ultimate, Apricotabs, Children's delicious vitamins, Omega 3/60, Protiviti, Colostrum (FirstFoot), Selenium, Zinc, etc.

The use of nutraceuticals in the daily diet of different population groups (children, young and elderly people, athletes, people with poor health) allows:

– compensate for the lack of essential nutrients in children and adults;

– take into account in the nutrition of each individual person his individual needs, which depend not only on gender, age, but also on the genetically determined characteristics of the metabolism of an individual organism, its biorhythms, environmental living conditions, physiological conditions (emotional stress, physical activity, etc. .);

– ensure that the sick person’s need for nutritional nutrients is maximized;

– increase the body’s protective response from the effects of adverse environmental factors;

– influence enzyme systems, accelerate and enhance the removal and binding of toxins and foreign substances from the body.

Parapharmaceuticals– these are natural remedies that have a targeted physiological effect and are used to prevent various diseases. Composition of parapharmaceuticals– complexes of bioactive substances isolated from plants: glycosides, alkaloids, phenolic compounds, enzymes, organic acids, phytoncides, saponins, essential oils, terpenoids, flavonoids, tannins, etc.


The vast majority of parapharmaceuticals are safe to use. Compared to medications, they have a beneficial healing effect on the functions of individual organs and systems of the body, with a significantly lower likelihood of side and toxic effects.

In large doses, these dietary supplements are already considered medicines.

Advantages of parapharmaceuticals over drugs:

1. Obtained from medicinal or food plants of an ecological niche;

2. They contain natural water- and fat-soluble complexes of biologically active natural components;

Action parapharmacists carried out in the following areas:

– systems that participate in the development of adaptive reactions of the body are activated;

– the functional activity of individual organs and systems is regulated;

– stimulates the activity of the nervous system, physical and mental performance;

– metabolism is regulated, as well as the motor-evacuation function of the gastrointestinal tract.

Parapharmaceuticals Company Coral Club– Diosin, Ant tree bark, Cat's claw, Herbal sets, Alfalfa, Black walnut leaves, Eyebright, Echinacea, etc.

Complex products – Microhydrin, Bioshape, spirulina products, Fito-Si, Enduro-max, etc.

coralvada.com

Story

Humanity has always faced seasonal and endemic food deficiencies (not taking into account starvation as such), and since ancient times empirical attempts have been made to cope with their consequences. Observations of animals were useful, and some traditions and ritual actions, when viewed from the perspective of nutritionology, look reasonable and not at all barbaric, such as drinking the blood of killed animals, still practiced in the far north. With the growth of the cultural level, man lost and suppressed some of the fundamental protective mechanisms, in return acquiring labor skills and intelligence, the rudiments of the economy to the detriment of biological expediency.

Man expanded his habitat without fundamentally changing the basic principle of solving the food program - accumulation, concentration, storage; the survival of the clan was paramount, and there was no talk about the variety and adequacy of nutrition, which in general terms has remained to this day.


The first written descriptions of strange diseases, as well as attempts to combat them, date back to the period of great conquests and long campaigns, when, for example, the captain was forced to load the ship with gunpowder, or even gold, at the expense of food, or an expedition that remained for the winter or was waiting for passing transport for several months she suddenly found herself stricken with an unknown disease that is not observed among the locals, or, even more remarkable, is called “alien disease.” Bleeding gums in combination with anemia and brittleness, deformed nails, called scurvy, was observed in those who were forced to give up fresh plant food, but lemon and wild bulbs, traditionally used by the aborigines for food, turned out to be a salvation; from the characteristic pain and convulsive syndrome (beriberi), common among European sailors who explored the coastal waters of Indochina, he was tired of yeast leaven; A characteristic skeletal deformation in children (rickets) was observed in families forced to economize on animal products, and a proven means of prevention was a steam extract of fat from the liver of cod or whale - fish oil.

Currently, experimental and hygienic research to substantiate the feasibility of using dietary supplements is an important area of ​​activity for many medical institutes.

Professor V.A. Dadali (Head of the Department of Biological Chemistry, Faculty of Medicine, State Educational Institution of Higher Professional Education, St. Petersburg State Medical Academy named after I.I. Mechnikov) advocates the active use of dietary supplements in the nutrition of the Russian population.

Several dietary supplement classification systems

Generations of dietary supplements by degree of technological modification of the product

  • natural concentrates of nutrients that are used as independent food products and food additives, as well as a factor in physiotherapy, etc.; for example: mineral spring water, salt deposits of marine and thermal origin, bee products, mumiyo, algae, fish caviar and liver (first generation);
  • food concentrates, food additives, herbs and their mixtures for making teas, traditional for the cuisine of many nations and suitable for long-term storage (usually by drying) (not to be confused with medicinal preparations, whose place is in herbal medicine); example: dried fruits, pickles, fermentation products (alcoholic and lactic acid);
  • extracts, extracts, tinctures (similar to herbal preparations); mixtures of extracts in the form of syrups, pastes, lozenges, briquettes, balms;
  • highly concentrated and pure extracts, artificial and synthetic vitamin preparations, phospholipid, polypeptide and glycoprotein complex preparations, which are widely used in pharmacology; the emergence and popularization of the above-mentioned means is the merit of researchers and the established medical industry;

  • preparations combining the advantages of all of the above, fortified food products enriched with “elite” strains of lactic acid bacteria, kefir and yogurt, the emergence of the term “dietary supplement”; the period was marked by the emergence of the dietary supplement industry itself, conflicts against the backdrop of competition;
  • a product involving high technologies - bioengineering, information; focused on maximum proximity to individual and immediate needs (in the process of formation);

By origin of the main components

  • plant extracts, whole plant parts
  • bee products
  • seafood
  • animal hoods
  • mineral components
  • fermentation products
  • biotechnology products
  • synthetic analogues of natural nutrients

Nutraceuticals, parapharmaceuticals and eubiotics

Dietary supplements are also conventionally divided into three groups:

Nutraceuticals are biologically active food additives used to correct the chemical composition of human food (additional sources of nutrients: protein, amino acids, fats, carbohydrates, vitamins, minerals, dietary fiber). The functional role of nutraceuticals is aimed at:

  • replenishment of the deficiency of essential nutrients;
  • targeted changes in the metabolism of substances;
  • increasing the body’s non-specific resistance to the effects of unfavorable environmental factors;
  • immunomodulatory effect;
  • binding and excretion of xenobiotics;
  • therapeutic nutrition.

The ultimate goal of using nutraceuticals is to improve a person's nutritional status, promote health, and prevent a number of diseases.

Parapharmaceuticals are biologically active food additives used for prevention, auxiliary therapy and support within the physiological boundaries of the functional activity of organs and systems. The daily dose of a parapharmaceutical or, in the case of a composition, the daily dose of the active principle of a parapharmaceutical, should not exceed a single therapeutic dose determined when using these substances as medicines, provided that the dietary supplement is taken at least twice a day. All plants included in parapharmaceuticals must be checked according to domestic and international regulatory documentation in terms of permission for their use in the food industry, as well as in medicinal teas and infusions in accordance with the requirements of: Russian Pharmacopoeia; foreign Pharmacopoeia; Methodological guidelines on the procedure for preclinical and clinical study of drugs of natural origin and homeopathic medicines (Ministry of Health and Medical Industry of the Russian Federation 04/08/94); Flavoring substance sand natural sources of flavourings, 111 ed, Council of Europe, 1981; Flavors and Fragrance Materials. A Worldwide reference list of materials used in compounding flavors and fragrances with sources of supply, 1993.

Eubiotics are biologically active food additives that contain live microorganisms and (or) their metabolites that have a normalizing effect on the composition and biological activity of microflora and motility of the digestive tract; Eubiotics sometimes include a substrate that promotes the growth of friendly flora, but is not absorbed by the human body. Probiotics are an accepted synonym for the concept of “eubiotics,” however, products that do not contain living flora completely fall under this category. The mentioned means are also generalized under the category of “microecological therapy means”.

The main differences between dietary supplements - parapharmaceuticals and drugs

  1. Dietary supplements - parapharmaceuticals in most cases are sources of natural food components that do not have nutritional value, but are classified as essential nutritional factors - organic components of food and medicinal plants, seafood and animal tissue components. Less commonly, the active ingredients of dietary supplements - parapharmaceuticals can be obtained by biotechnological or chemical methods. Dietary supplements - parapharmaceuticals also include products prepared on the basis of compositions of microorganisms intended to normalize and maintain intestinal microbiocenosis (eubiotics/probiotics).
    The active principles of dietary supplements - parapharmaceuticals specifically support or regulate, within physiological limits, the functions of individual organs and systems. They are used exclusively “per os”. They are sold freely both through special departments of grocery stores and through the over-the-counter departments of pharmacies. When using dietary supplements - parapharmaceuticals as aids in the diet therapy of human diseases or as specific preventive agents, consultation with a specialist doctor is necessary before using them.
  2. The effect of dietary supplements - parapharmaceuticals is realized by initiating universal mechanisms of adaptive reactions of the body to the influence of irritants of a very different nature.
  3. Quantitative changes in the functioning parameters of the body's systems and organs are within the limits of their physiological norm.
  4. A wide (much more than that of drugs) range of doses used at which dietary supplements - parapharmaceuticals have a normalizing and corrective effect on the functions of individual organs and systems of the human body in the absence of toxic and side effects.

Legislative regulation

Terminology in Russia

According to Russian legislation - Order of the Ministry of Health of the Russian Federation No. 117 dated April 15, 1997 “On the procedure for examination and hygienic certification of biologically active food additives” introduces the following terminology:

  • Biologically active food additives (nutraceuticals and parapharmaceuticals) are concentrates of natural or natural-identical biologically active substances intended for direct intake or introduction into food products in order to enrich the human diet with individual biologically active substances or their complexes.
  • Biologically active food additives (BAA) are obtained from plant, animal or mineral raw materials, chemical or biotechnological methods. These include enzyme and bacterial preparations (eubiotics), which have a regulating effect on the microflora of the gastrointestinal tract.

Registration requirements in Russia

To obtain legal status on the territory of the Russian Federation, each specific name of dietary supplement is subject to state registration with the issuance of an appropriate certificate. The issuance and cancellation of certificates is carried out by the Federal Service for Supervision of Consumer Rights Protection and Human Welfare.

On August 10, 1998, the Russian Government approved the concept of state policy in the field of healthy nutrition, in which dietary supplements play a significant role. Professor V. Knyazhev, Deputy Minister of Science and Technology of Russia, wrote on this occasion: “The implementation of the concept of state policy... provides for the development of domestic industry:... the production of biologically active food additives (BAA), which make it possible to quite easily and quickly compensate for the deficiency of essential nutrients. The use of dietary supplements increases the body’s nonspecific resistance to unfavorable environmental factors, opens up a safe, non-drug way to regulate and support the functions of individual organs and systems of the body, thereby reducing morbidity, improving health, and prolonging life...”

According to the legislation currently existing in Russia, dietary supplements, before their introduction to the mass consumer, undergo careful and comprehensive control at the Certification Center of the State Sanitary and Epidemiological Supervision of the Russian Federation, and long-term clinical studies confirming their effectiveness. That is why only research institutes and companies with high scientific and technical potential have the opportunity to develop dietary supplements.

Features of the development and control of dietary supplements

The basis for recommendations for the use of dietary supplements are clinical trials. Moreover, the requirements for conducting such studies are quite stringent and require the mandatory inclusion of a whole range of modern methods, available only in large research and clinical institutions. Moreover, clinical trials can only be conducted in medical institutions accredited to conduct such studies in the manner established by the Ministry of Health of the Russian Federation. A list of such institutions has been approved.

Before conducting clinical trials, laboratory tests of new products are carried out. For example, to experimentally study the immunomodulatory effect of dietary supplements, a set of studies using laboratory animals is recommended to determine the following indicators:

  • the effect of dietary supplements on nonspecific resistance of mice to bacterial infection;
  • the level of antibodies in the blood serum of mice to the corpuscular thymus-dependent antigen, as well as to the soluble thymus-dependent antigen;
  • polyclonal activity of B lymphocytes;
  • delayed type hypersensitivity to sheep red blood cells;
  • phagocytic activity of macrophages;
  • production of soluble mediators of immunogenesis - cytokines tumor necrosis factor and interleukin-2;
  • T-lymphocyte proliferation in cyclosporine-induced immunosuppression; humoral immune response.

When conducting clinical trials of dietary supplements that have, for example, choleretic and hepatoprotective properties, the mandatory research methods include:

  • study of the biliary function of the hepatobiliary system using duodenal intubation;
  • ultrasound examination of the gallbladder and liver;
  • determination of such biochemical blood parameters as cholesterol, bilirubin, enzymes alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and amylase;
  • as well as carrying out thymol and sublimate tests.

Application

Biologically active food additives are used:

  • to replenish insufficient dietary intake of protein and individual essential amino acids, lipids and individual fatty acids (in particular, polyunsaturated higher fatty acids), carbohydrates and sugars, vitamins and vitamin-like substances, macro- and microelements, dietary fiber, organic acids, bioflavonoids, essential oils, extractives, etc.;
  • to reduce calorie intake, regulate (decrease or increase) appetite and body weight;
  • to increase non-specific resistance of the body, reduce the risk of developing diseases and metabolic disorders;
  • to carry out the regulation of body functions within physiological boundaries;
  • for binding in the gastrointestinal tract and removing foreign substances;
  • to maintain the normal composition and functional activity of intestinal microflora.

Initially, dietary supplements were considered as a compensatory supplement to the diet of people who have increased requirements for any (missing) components of normal nutrition (for example, athletes). Later, dietary supplements began to be considered a means of disease prevention, which naturally leads to the question of individualizing the prescription of dietary supplements and the development of “individual dietary supplements” (see metabonomics).

Currently, the following areas are considered separately from dietary supplements:

  • Sports nutrition
  • Functional nutrition
  • Diet food
  • Preventive nutrition (in enterprises)
  • Government programs for the introduction of additives of certain substances into food products for the population (for example, iodides or periodates in salt (“Iodized salt”) in regions of natural geological depression of iodine in the environment).

Features of selling dietary supplements in Russia

Unlike medicines, Russia does not provide mandatory certification or declaration (quality testing by independent laboratories) of each batch of dietary supplements.

The quality of dietary supplements is checked almost exclusively during production, which is often taken advantage of by unscrupulous manufacturers, violating technology and recipes. In addition, clinical studies of the use and effect of dietary supplements are not mandatory. All of the above, combined with unreliable (and often aggressive) advertising, creates fertile ground for fraud and deception in the production and sales of dietary supplements.

In the Russian Federation, examination of documentation, medical and biological assessment, sanitary-chemical, microbiological and other necessary studies of dietary supplements, as well as, if necessary, making a decision on their clinical testing, are entrusted to the Center for Hygienic Certification of Food Products of the Department of Sanitary and Epidemiological Surveillance of the Ministry of Health of the Russian Federation , which is located on the basis of the Institute of Nutrition of the Russian Academy of Medical Sciences. In some cases, this work is carried out jointly with other authorized institutions.

On dietary supplements that have passed state registration in accordance with the Decree of the Chief State Doctor of the Russian Federation “On state registration of biologically active food additives” No. 21 of September 15, 1997. A federal register of biologically active additives (BAA) is maintained. The main document giving the right to trade dietary supplements in the Russian Federation is the registration certificate. The reliability of the latter is checked according to the Register on the official website of Rospotrebnadzor http://fp.crc.ru. The certificate contains information about the name of the dietary supplement, the manufacturer and recipient of the certificate for the dietary supplement, their addresses, the certificate number and the date of its issue, the scope of application of the dietary supplement, the composition and hygienic characteristics of the dietary supplement.

The production, circulation and sale of dietary supplements in the Russian Federation is regulated by SanPiN 2.3.2.1290-03. The right to produce, use, sell dietary supplements on the territory of the Russian Federation, as well as import dietary supplements, is given by the Certificate of State Registration (SGR). The list of dietary supplements that have passed state registration is contained in Federal Register of dietary supplements, for which Rospotrebnadzor is responsible. Information about dietary supplements, agreed with Rospotrebnadzor, is open and kept up to date on its Search server. The SGR is valid for the entire period of production of dietary supplements, i.e. is actually an indefinite document. Before the introduction of the state registration procedure, dietary supplements underwent a sanitary and epidemiological examination, the results of which were included in the sanitary and epidemiological report (SEZ) or registration certificate (RU). These documents were valid for 3-5 years, after which a re-examination was necessary. All SEZs and RUs, the validity of which has not yet expired, continue to be valid together with the SGR for newer dietary supplements. Information about the majority of existing SEZs and RUs is also included in the database of the Rospotrebnadzor Search Server.

The sale of dietary supplements is not allowed:

  • have not passed state registration;
  • without a certificate of quality and safety;
  • not meeting sanitary rules and standards;
  • expired;
  • in the absence of appropriate conditions for implementation;
  • without a label, as well as in the case when the information on the label does not correspond to that agreed upon during state registration;
  • in the absence of information on the label in accordance with the requirements of current legislation.

In accordance with SanPiN 2.3.2.1290-03“Hygienic requirements for the organization of production and circulation of biologically active food additives (BAA)” retail trade of dietary supplements can only be carried out through pharmacies (pharmacies, pharmacy stores, pharmacy kiosks and others), specialized stores selling dietary products, food stores (special departments , sections, kiosks).

see also

  • Vitamins
  • Dietetics
  • Nutritionology
  • Cosmeceuticals
  • Dietary supplements
  • Nutritional supplements
  • Artlife
  • UES Register of dietary supplements

Notes

  1. http://www.mechnik.spb.ru/podrazdel_academy/faculty/kaf/kafedra_gigieny_pitaniya_i_dietologii_s_kursom_gigieny_detei_i_podrostkov/index.php
  2. http://www.mechnik.spb.ru/podrazdel_academy/faculty/kaf/kafedra_tradicionnoi_mediciny_i_gomeopathy/index.php
  3. http://vision.rambler.ru/users/best4link/1/1/
  4. Guidelines MUK 2.3.2.721-98
  5. http://www.golkom.ru/book/31_7.html
  6. see above

dic.academic.ru

Let's figure out what it is

"What is it?" - you will probably ask, and we will have an answer. Nutraceuticals are a special type of dietary supplements (biologically active additives), the main task of which is to replenish the reserves of vitamins, minerals and other biologically active substances that are necessary for normal human life. If we get some of the nutrients that cannot be synthesized in our body from consumed foods, then nutraceuticals should make up the rest. The very concept of “nutraceuticals” is a synthesis of the words “Nutrition” and “Pharmaceutical”. In other words, it is a way of eating that simultaneously has medicinal potential for the prevention and prevention of disease.
The most well-known and understandable example of nutraceuticals is sports nutrition. After all, this is a protein powder that not only contains the ideal dose of protein for our body, but also helps replace meals. That is why nutraceuticals are called ideal nutrition - they bring the content of nutrients in the human body to the level at which a person’s daily needs are.
What effects can nutraceuticals have on the human body:
they replenish the reserves of essential nutrients in the human body;
allow you to individualize nutrition;
increase immunity;
remove toxins;
speed up metabolism (and therefore promote weight loss);
improve performance;
help prevent the development of obesity, cancer, osteoporosis.

Depending on the set of nutrients, certain types of nutraceuticals are distinguished:
vitamin-mineral complexes (these are the usual combinations of vitamins and minerals);
antioxidant complexes (vitamins A, C, as well as enzymes and bioflavonoids);
preparations with polyunsaturated fatty acids (for example, omega-3 and omega-6);
preparations with substances that are sources of phospholipids (for example, licentine);
preparations that contain dietary fiber (pectin, chitin, etc.).