Can children be allergic to Creon? Allergy to Creon - two options for the reaction Insufficiency of pancreatic function in various nosologies

A pediatric dermatologist prescribed the drug Creon 10,000 to us for a 4-year-old child. The fact is that we have food allergies, as well as drugs, especially syrups. The child develops atopic dermatitis due to food allergy. The rashes appear mainly on the elbows, which redden, itch terribly, that the child scratches the skin until it bleeds, and the skin is very rough on the elbows.

When our pediatrician saw this, he immediately referred to a pediatric dermatologist.

After examination, the doctor prescribed a comprehensive treatment and diet.

In the treatment was prescribed the drug Creon 10000. It is available in capsules. Sold in jars, as well as in cardboard boxes. We bought this one in a cardboard box.

We were prescribed a clear dosage based on the weight of the child. I will not paint it, since everything is individual.

In the instructions, everything is very conveniently painted.

Although the capsules, as for me, are too big for a child of this age. But we had no problems with taking this drug.

Creon 10000 is intended for the stomach, compensates for the deficiency of pancreatic enzymes. He helped us a lot. Atopic dermatitis is gone. The skin became clear and no more rashes.

Regarding allergies, the pediatrician told us, so that - this can be for life, or maybe the child will outgrow.

And in general, to improve the digestion process and eliminate problems, Creon is one of the best.

Adequate nutrition provides the body with the substances necessary for life, therefore, allergic reactions that are provoked by the intake of a particular food require treatment. Special attention should be paid to atopic dermatitis, which is a chronic condition in which the human immune system does not adequately respond to certain types of food.

Modern medicine classifies food intolerances into the following groups:

True food allergy associated with immunological mechanisms;

Pseudo-allergic manifestations associated with the histamine-liberating properties of food additives and certain types of food;

Psychogenic reactions to consumed foods;

Food allergy caused by a deficiency of digestive enzymes.

Active substance

Pancreatin

Composition and form of release

Creon capsules 10000/25000. 1 capsule contains: pancreatin 150/300 mg; amylase 8000/18000 U EF; lipase 10000/25000 U EF; protease 600/1000 U EF. Excipients: macrogol; liquid paraffin; methylhydroxypropylcellulose phthalate; dimethicone 1000; dibutyl phthalate. Capsule shell: iron oxide red (E172); iron oxide black (E172); iron oxide yellow (E172); titanium dioxide (E171); gelatin. Capsules are available in blister packs of 10; in a pack of cardboard 2 blisters; in a blister 25 pcs.; in a pack of cardboard 2 or 4 blisters; in polyethylene bottles of 20 and 50 pcs .; in a pack of cardboard 1 bottle.

Pharmacological group

Digestive enzyme remedy.

pharmachologic effect

Replenishment of the deficiency of pancreatic enzymes. Creon is a gelatin capsule consisting of mini-microspheres with porcine pancreatin. Gelatin capsules tend to dissolve rapidly in the stomach, releasing microspheres, which are enteric-coated and easily miscible with gastric contents. After dissolution, Creon, together with the food lump, enters the small intestine, where the microsphere shell dissolves and the active substance is released.

The active ingredient of the drug Creon has the ability to break down fats (lipolytic effect), carbohydrates (amylolytic effect) and proteins (proteolytic effect) after which food is absorbed in the intestine. Creon is practically not absorbed, exerting a pharmacological effect in the intestinal lumen.

Digestion of food is a physiological function of the gastrointestinal tract. As a result of the work of the digestive system, complex chemical compounds that are contained in food are broken down into smaller particles, which become available for assimilation by the body and serve as building materials for muscles, bones, nourish the brain, nervous system, and give energy for life. Therefore, experts believe that understanding the mechanisms of development of food intolerance, including atopic dermatitis, is impossible without assessing the work of the digestive system.

The process of digesting food begins in the mouth, during chewing. The food lump is crushed and exposed to the alkaline environment of enzymes that are found in saliva. The further digestion process continues in the acidic environment of the stomach. Bile breaks down fats, pancreatic enzymes process starch, fiber, muscle fibers. Subsequently, the chyme (food lump) undergoes final digestion in the intestinal juices.

In the case when the digestive system does not produce the required amount of certain enzymes and / or when the intestinal microflora is disturbed, the conversion of the antigen (allergen) into a substance neutral for the body is hampered and an allergic reaction occurs, which can manifest itself in the form of skin rashes or more serious and dangerous manifestations, such as swelling or difficulty breathing. That is why, in the complex therapy of atopic skin reactions, drugs can be prescribed that replenish enzyme deficiency, for example, the "Creon" remedy for atopic dermatitis.

Indications for use

Creon is used as a replacement therapy for enzymatic deficiency caused by the following diseases:

chronic course of pancreatitis;
condition after pancreatectomy;
condition after gastrectomy;
cystic fibrosis;
Schwachman-Diamond syndrome;
pancreatic cancer or other tumor causing obstruction of the pancreatic or bile duct;
condition after surgery with the imposition of a gastrointestinal anastomosis (for example, according to Billroth-II);
other diseases associated with a deficiency of pancreatic enzymes, including atopic dermatitis.

Reviews about the treatment of atopic dermatitis in children on the website of a well-known pediatrician dispelled my doubts about whether to use "Creon" for allergies in a child or not. I was worried that giving a child enzymes was evil, since then my own enzymes would stop being produced at all. It turns out that in reality everything is somewhat different and there is nothing wrong with the treatment with the use of the "Creon" remedy. There are practically no side effects (as in our case), and substances that can cause allergies are easily split into harmless ones and are absorbed by the body. I gave my daughter Creon for 14 days with meals. In combination with the use of antihistamines and capsules that improve the microflora in the intestines, the enzymes worked wonderfully. My daughter's stool became regular (although there used to be a tendency to constipation), the heaviness in the abdomen after eating stopped, rashes on the cheeks and in the folds of the arms, which began to redden and itch after 20 minutes after any meal, disappeared, although dry skin and slight peeling persist.

Method of administration and dosage

Creon is prescribed depending on the nosology that caused the indigestion, the severity of the disease and the patient's diet. In order to be able to adequately select the dosage, there are several forms of the drug, with different contents of the active substance in the capsules: Creon 10 thousand, 25 thousand, 40 thousand. It is recommended to use the drug Creon during any meal, both main and additional ... It is advisable to swallow the capsules without chewing, drinking plenty of water or other neutral liquid. If it is impossible to swallow the capsule, its opening is allowed, and the dissolution of microspheres in liquid food that has a neutral medium (for example, yogurt or grated apple), the mixture of microspheres with food must be consumed immediately, its storage is unacceptable. During Creon therapy, it is very important to observe an adequate drinking regime, with a lack of fluid, stool disorders (constipation) are possible.

Cystic fibrosis

The initial dosage for children under 4 years of age is 1 thousand units of lipase per kilogram of the child's body weight 3-4 times a day (during each meal), for children over 4 years old is 0.5 thousand units of lipase per kilogram of the child's body weight , 3-4 times a day (during each meal), the maintenance dosage of the drug is selected individually, depending on the severity of the condition and objective research data and usually does not exceed 10 thousand units of lipase per kilogram of body weight per day.

Lack of pancreatic function in various nosologies

The dose of Creon is selected individually, depending on the nosology, the degree of indigestion and other factors. In most cases, the initial dosage is from 10 thousand to 25 thousand units of lipase during each meal. The maintenance dosage is calculated depending on the nature of the food, the degree of exocrine pancreatic insufficiency and on average ranges from 20 thousand to 75 thousand units of lipase during each main meal and from 5 thousand to 25 thousand units of lipase during additional meals ...

Drugs that replenish enzyme deficiency are prescribed for atopic dermatitis in adults and children. It is worth noting that just taking enzymes to stop an allergic reaction and prevent the subsequent development of skin rashes may not be enough. As a rule, the treatment of atopic dermatitis involves a set of measures: the use of antihistamines, anti-inflammatory, hormonal, sedatives. Self-medication for atopic dermatitis is unacceptable!

Side effects

The incidence of side effects when taking Creon is comparable in frequency with the occurrence of adverse reactions when taking a placebo.

Rarely there are side effects from the gastrointestinal tract (stool disorders, abdominal pain, dyspeptic disorders) and allergic skin reactions.

Contraindications

Contraindication to the appointment of Creon is acute pancreatitis with pancreatic hyperfunction, intolerance to porcine pancreatin or any of the auxiliary components of the drug.

special instructions

In patients with cystic fibrosis who took other drugs of pancreatin in high doses, fibrosing colonopathy (narrowing of some parts of the small intestine and colon), as well as colitis, were sometimes diagnosed. In the studies of Creon, such an effect was not noted, however, in such patients during treatment with Creon, careful monitoring of possible bowel changes should be carried out.

Perhaps the use of Creon in children.

The absence of systemic effects allows the use of Creon in women during lactation.

Creon does not affect the rate of mental reactions and can be used in patients working with complex mechanisms or driving vehicles.

More often, Creon, on the contrary, helps to cope with allergies, as it removes toxic products formed during digestion.

Allergy to Creon - why and how it develops

The active active ingredient of Creon are pancreatic enzymes, which are obtained from the pancreas of pigs. Enzymes are catalytic proteins that regulate the processes of life and metabolism Metabolism: the basis of the life of all living things in the body. Pancreatic enzymes help digest the main food ingredients - proteins, fats and carbohydrates.

Allergy is an inadequate reaction of the body to the ingress of a substance into it. Allergy to proteins of animal origin is a fairly common phenomenon. Allergy to Creon is especially common in people who are intolerant to pork. There may also be an allergy to the excipients that make up the capsules and their contents.

Excipients of Creon Creon - a medicine that will help digestion are macrogol 4000, hypromellose phthalate, dimethicone 1000, cetyl alcohol, triethyl citrate. The capsule shell contains gelatin, iron dye red oxide, iron dye yellow oxide, titanium dioxide, sodium lauryl sulfate. Any of these substances may be allergic.

When you are allergic to a drug, in response to the ingress of an allergen, a number of biologically active substances are produced in the body, which cause an allergic reaction.

Allergy to Creon manifests itself in the form of a skin rash of a different nature, which is often accompanied by itching. The most common type of rash is urticaria, a rapidly growing red blister on the skin that can coalesce. Hives can develop quickly and disappear just as quickly. But this is not a harmless reaction. With its rapid growth, edema can go to the subcutaneous tissue and the soft tissues located under it. The danger is the transition of edema to the region of the larynx and vocal cords: the increased volume of soft tissues can block the access of air to the lungs. It is possible that allergies may appear in the form of eating disorders - nausea, vomiting, loose stools. Liquid stools - indigestion, bloating and abdominal pain.

If an allergy develops, you should stop taking Creon immediately and consult a doctor.

How Creon can help with allergic diseases

Allergy to Creon is not so common. But to reduce allergies, Creon is taken. The mechanism of action of Creon in this case is due to the fact that it contributes to the correct splitting of food ingredients, their rapid absorption into the bloodstream and the rapid elimination of toxic products formed during digestion from the body. Much less toxic products are formed during digestion when using Creon than without it.

Very often, allergies appear from birth. This is a congenital allergy that manifests itself in the form of skin lesions - atopic dermatitis. In the future, skin manifestations can turn into other types of allergies, including bronchial asthma.

With allergies, the whole body always suffers. Allergens cause multiple immunological and biochemical processes, as a result of which a large amount of a number of biologically active substances (histamine, serotonin, etc.) enter the bloodstream, which negatively affects all organs and tissues.

This happens due to the effect of these substances on the walls of small blood vessels that feed various organs and tissues. With different allergic reactions, different organs and tissues can suffer, but almost always the pancreas is involved in the allergic process, which is associated with the peculiarities of the structure and blood supply of this organ. Even a slight violation of blood circulation leads to edema of the pancreas, which in turn leads to a decrease in the supply of oxygen and nutrients to the cells of the gland.

At the same time, the pancreas also has significant compensatory capabilities, so a person does not feel any changes. If allergic reactions continue for a long time, the function of the pancreas. Diabetes and pancreas - things that need to be known are reduced and digestive disorders occur with the formation of toxic substances that increase the phenomenon of allergies.

Thus, with allergic diseases, changes in the pancreas almost always occur. That is why Creon is often prescribed as part of the complex treatment of allergic diseases.

Who gave children Creon for atopic dermatitis?

Mobile application "Happy Mama" 4,7 Communication in the application is much more convenient!

Most often atopic. dermatitis due to problems in the intestines. it is necessary to take the analysis for dizb-z first of all. And if only from the outside to treat, there will be no sense.

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Take no more than 2 weeks, since the pancreas will begin to be lazy and stop producing enzymes by itself, and this should not be allowed. The doctor prescribes the dosage. And a strict diet, nothing can be done, will have to be followed for a long time 🙁

Recently, a gastroenterologist came to the child, some kind of luminary, said that Creon should not be abused, you have already been told why above.

follow a diet, eat new foods with caution. maybe it makes sense to consult someone else?

yeah, but we were prescribed for anemia, I didn't give a fig to the child.

but here's the indications for use:

* pancreatic cancer;

* ductal obstruction due to neoplasm (for example, obstruction of the pancreatic duct or common bile duct);

Symptomatic therapy of digestive disorders in the following cases:

* conditions after cholecystectomy;

* partial gastric resection (billroth-i / ii);

* duodeno- and gastrostasis;

* cirrhosis of the liver, pathology of the terminal section of the small intestine;

* bacterial overgrowth in the small intestine.

Eh, I understand. what selfishness, but sitting on one oatmeal for a whole year. Yes, and there is nowhere to lose weight, with an increase of 158 I weigh 47 kg.

daladna 🙂 my friend, with a height of 155, weighs 43 kilos and nothing :))

and I myself, with the same height as yours, constantly flew when I weighed 48 kg :))

everything was the same with us (right now we are 6 months old), the current is also arching and getting up on the bridge from pain (COLICI) has stopped eating a lot, but cheese, cottage cheese, curazza (I can't look at her), porridge - that's our food. about Creon: they drank - the contents of 1 torpedo is divided into three parts and is given during the day (they drank until the whole bank is over) there are not so many of them)))), but we also showed on the ultrasound of internal organs that the pancreas is not quite formed, so we just needed mezim and creon, right now - ugh, ugh, we eat it ourselves and, OH, HAPPINESS - we poop ourselves (from four months already without pills and a GAS EXHAUST tube) we eat everything, and the child eats beet and pumpkin purees, so that Creon helped us.

you should not abuse enzymes, babies already have an immaturity of the enzymatic system, and with artificial enzymes, the body will generally become lazy and will work poorly. Diet, diet and again diet. I kept a food diary, the time that I ate myself (HS), that the child, the manifestation of allergies, increased rashes, diarrhea or something else. And so I figured out what is possible and what is not. It seems that an allergy manifests itself when an allergen arrives from 2 to 8 hours.

After a year and a half, all our allergies disappeared, and for up to a year they ate boiled and stewed zucchini.

Your answer is encouraging, maybe we will be better by six months. I also keep a food diary, but there's no sense in it.

if the child is very worried about rashes, ask the doctor if enterosgel is possible, it helped us a lot to remove the external manifestations of allergies, but when the allergen was ingested, everything crawled out again.

and how much should you give it? and how did you give, with a spoon, diluted with water?

By the way, I noticed such a pattern, the greatest manifestation of allergies was at 3.6 and 9 months. It seems that children have something with the maturation of the immune system during these periods, so there is a surge of allergic reactions, I read about it somewhere, I don't remember where.

By the way, yes, it is the same with us. 6 months was strong, now 9, again a rash is coming up.

the pediatrician persistently prescribed creon for us because of allerg rash. She didn’t give. My mom drank Creon after removing the gallbladder .. in theory, this is a very strong medicine. And she told me not to do it in any case - the pancreas will not learn to work on its own. On a strict diet for six months. Well, what to do? The improvements are very slow, but still there. I really hope that it will eventually outgrow when everything in the gastrointestinal tract will tune in by itself. here)) so bear with it;))

and by the way, also 158 .. and already probably also somewhere around 47. baby 9m, pronounced rash from 3

could not find out what? Did you do something, treated with medication, or just a diet?

Does the child have problems with stool?

I will write about my experience: they were also all sprinkled, up to wet corroded areas on the neck. I gradually switched to a strict diet, by the way, with the growth of 163, I dropped to 46 kg - feel the difference, as they say. The husband threatened to stop the Guards.

And by about six months, everything came to naught by itself, began to eat everything, including chocolate, etc. When you take a general blood test, there is an indicator that is responsible for allergies (I don’t know what it’s called) and we didn’t have allergies as such. Therefore, it is not at all necessary that you have a food allergy, perhaps it is just that an immature body cannot normally digest certain foods. this is a temporary difficulty. But there is no allergy to this or that product.

Now I slowly, with a 2-week interval, introduce all the products (complementary foods) and there was no reaction to anything else (pah-pah). So my advice is to endure at least half a year, let the small body grow stronger, and then make decisions. Although I would not give any medicine in this case either.

That is, there was no allergy to the blood, even when the rash was present?

And do you feed when everything has already passed?

yes, there was diathesis, but there was no allergy in blood. those. it was just a temporary reaction of the body to food, due to immaturity, which eventually passed.

Complementary foods began to be introduced from 6 months, diathesis already by this time was not. and the products are all accepted ok. True, complementary foods, due to such a past, began with cereals and zucchini - the most non-allergenic products.

Oh, thanks, I need to see a blood test, just recently took

For children with allergies

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Creon for the treatment of food allergies, who has tried it?

The child is 3 months old, full of hepatitis B. Reacts very strongly to foods I eat. Our doctor, in response to my concern about the child's rash, advised me to try Creon, supposedly enzymes will help break down allergens. Has anyone tried this to treat food allergies? Was there an effect?

On the one hand, I don't really want to feed the child with drugs, but on the other, what if it helps, and, lo and behold, I can eat whatever I want? Now I am on a strict diet, but a step to the left, a step to the right is immediately punishable by a rash and red cheeks. Has lost 4 kg in 3 months.

How much should you take? Do I need to go on a diet at this time or can I slowly try other foods?

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Creon with atopic dermatitis: instructions for use, reviews

Adequate nutrition provides the body with the substances necessary for life, therefore, allergic reactions that are provoked by the intake of a particular food require treatment. Special attention should be paid to atopic dermatitis, which is a chronic condition in which the human immune system does not adequately respond to certain types of food.

Modern medicine classifies food intolerances into the following groups:

True food allergy associated with immunological mechanisms;

Pseudo-allergic manifestations associated with the histamine-liberating properties of food additives and certain types of food;

Psychogenic reactions to consumed foods;

Food allergy caused by a deficiency of digestive enzymes.

Active substance

Composition and form of release

Pharmacological group

Digestive enzyme remedy.

pharmachologic effect

Digestion of food is a physiological function of the gastrointestinal tract. As a result of the work of the digestive system, complex chemical compounds that are contained in food are broken down into smaller particles, which become available for assimilation by the body and serve as building materials for muscles, bones, nourish the brain, nervous system, and give energy for life. Therefore, experts believe that understanding the mechanisms of development of food intolerance, including atopic dermatitis, is impossible without assessing the work of the digestive system.

The process of digesting food begins in the mouth, during chewing. The food lump is crushed and exposed to the alkaline environment of enzymes that are found in saliva. The further digestion process continues in the acidic environment of the stomach. Bile breaks down fats, pancreatic enzymes process starch, fiber, muscle fibers. Subsequently, the chyme (food lump) undergoes final digestion in the intestinal juices.

In the case when the digestive system does not produce the required amount of certain enzymes and / or when the intestinal microflora is disturbed, the conversion of the antigen (allergen) into a substance neutral for the body is hampered and an allergic reaction occurs, which can manifest itself in the form of skin rashes or more serious and dangerous manifestations, such as swelling or difficulty breathing. That is why, in the complex therapy of atopic skin reactions, drugs can be prescribed that replenish enzyme deficiency, for example, the "Creon" remedy for atopic dermatitis.

Indications for use

Creon is used as a replacement therapy for enzymatic deficiency caused by the following diseases:

chronic course of pancreatitis;
condition after pancreatectomy;
condition after gastrectomy;
cystic fibrosis;
Schwachman-Diamond syndrome;
pancreatic cancer or other tumor causing obstruction of the pancreatic or bile duct;
condition after surgery with the imposition of a gastrointestinal anastomosis (for example, according to Billroth-II);
other diseases associated with a deficiency of pancreatic enzymes, including atopic dermatitis.

Reviews about the treatment of atopic dermatitis in children on the website of a well-known pediatrician dispelled my doubts about whether to use "Creon" for allergies in a child or not. I was worried that giving a child enzymes was evil, since then my own enzymes would stop being produced at all. It turns out that in reality everything is somewhat different and there is nothing wrong with the treatment with the use of the "Creon" remedy. There are practically no side effects (as in our case), and substances that can cause allergies are easily split into harmless ones and are absorbed by the body. I gave my daughter Creon for 14 days with meals. In combination with the use of antihistamines and capsules that improve the microflora in the intestines, the enzymes worked wonderfully. My daughter's stool became regular (although there used to be a tendency to constipation), the heaviness in the abdomen after eating stopped, rashes on the cheeks and in the folds of the arms, which began to redden and itch after 20 minutes after any meal, disappeared, although dry skin and slight peeling persist.

Method of administration and dosage

Cystic fibrosis

Lack of pancreatic function in various nosologies

Drugs that replenish enzyme deficiency are prescribed for atopic dermatitis in adults and children. It is worth noting that just taking enzymes to stop an allergic reaction and prevent the subsequent development of skin rashes may not be enough. As a rule, the treatment of atopic dermatitis involves a set of measures: the use of antihistamines, anti-inflammatory, hormonal, sedatives. Self-medication for atopic dermatitis is unacceptable!

Side effects

The incidence of side effects when taking Creon is comparable in frequency with the occurrence of adverse reactions when taking a placebo.

Rarely there are side effects from the gastrointestinal tract (stool disorders, abdominal pain, dyspeptic disorders) and allergic skin reactions.

Contraindications

Contraindication to the appointment of Creon is acute pancreatitis with pancreatic hyperfunction, intolerance to porcine pancreatin or any of the auxiliary components of the drug.

special instructions

Perhaps the use of Creon in children.

The absence of systemic effects allows the use of Creon in women during lactation.

Creon does not affect the rate of mental reactions and can be used in patients working with complex mechanisms or driving vehicles.

A swollen tummy, colic and severe pain in children often worries young mothers and fathers. Every parent knows firsthand what it is when your child does not sleep well, cries all the time and suffers from fever and abdominal pain.

Basically, this comes from malnutrition and a weak child's body. In such situations, the powerful drug Creon 10000 comes to the rescue, which helps to eliminate the discomfort of the gastrointestinal tract and significantly improves the condition of the child. But what to do if after the first application your baby is covered with red inflammation all over the body? Let's figure it out!

Please note that if your child is from 3 weeks to 3 months, then colic in the abdomen is a normal phenomenon that every baby goes through, so there is no need to treat and give him various medications.

What is Creon?

Creon 10000- This is one of the most effective enzyme preparations, consisting of pancreatic substances that help the body to better digest food and cleanse it of toxic enzymes. With it, proteins, fats and carbohydrates are better processed and absorbed in the small intestine. It also improves bowel and pancreatic function.

It can be taken by both adults and children of any age, and even babies (only on the recommendation of doctors). The dose of the drug and the frequency of use depends exclusively on the individual from each client, taking into account the degree of the disease and the state of the body as a whole. During use, the capsules must be swallowed completely and washed down with a small amount of water.

Allergy Causes

All medications, without exception, have negative reactions and side effects. The most common ones are headache, increased level of fatigue, disturbed sleep, nausea, etc. But, one of the biggest disadvantages of Creon on the part of the skin and subcutaneous tissue is allergy.

This is due to the fact that when a drug enters the body, a variety of biologically active substances begin to reproduce there, due to which an allergic reaction appears on the skin. Hypersensitivity of children's organs instantly reacts to allergens in the medicine.

Another reason for allergies is the release of a substance by the child's body, such as histamine that help inflammation to manifest itself on the skin tissues.

Allergy symptoms

The most common type of allergic reaction in children is hives... It manifests itself as red blisters on certain parts of the body, these spots can join together, and they are almost always accompanied by itching. It most often appears on the hands, face, joints or airways, and sometimes it can exhibit fever.

It is easy enough to get rid of it, but it is important to know that if you allow hives to a neglected state, then it can negatively affect the subcutaneous tissue and soft tissues under it. There is a danger if edema enters the larynx and vocal cords, since the formed new soft tissues can block the access of oxygen to the body.

Also, an allergy from Creon can manifest itself as violation of the gastrointestinal tract... Most often it is vomiting, nausea, dry mouth, diarrhea, constipation, abdominal pain, etc.

How to eliminate allergies?

Getting rid of an allergic reaction in a child will not be difficult.

At the first signs of rashes and pain, you should immediately contact a gastroenterologist. It is important to remember the famous phrase for everyone - self-medication can be dangerous to your health (and the health of your children).
If you know for sure that your child is sprinkled with Creon, stop using it right away. Find alternatives to this drug in the form of other drugs.
Start applying ointments or products directly from the rash itself.
After consulting a dietitian, try changing your baby's diet. This will give you a better chance of finding out the root cause of the problem and fixing it.

It is important to know that if you or your child have any of the diseases listed below, then taking Creon 10000 is strictly prohibited.

Contraindications:

Chronic pancreatitis with acute exacerbation.
High sensitivity to the components of the drug (for example - porcine pancreatitis).
Acute pancreatitis.

Remember, when newborn babies are faced with allergic reactions, rashes and disorders, you need to immediately react and take some measures. So, as some allergy symptoms can smoothly turn into others, thereby infecting your child's body with new diseases of varying severity. Therefore, more often try to visit medical institutions, carry out health preventive measures and do not forget to monitor your baby.

Active substance

Pancreatin

Composition and form of release

Pharmacological group

Digestive enzyme remedy.

pharmachologic effect

Digestion of food is a physiological function of the gastrointestinal tract. As a result of the work of the digestive system, complex chemical compounds that are contained in food are broken down into smaller particles, which become available for assimilation by the body and serve as building materials for muscles, bones, nourish the brain, nervous system, and give energy for life. Therefore, experts believe that understanding the mechanisms of development of food intolerance, including atopic dermatitis, is impossible without assessing the work of the digestive system.

The process of digesting food begins in the mouth, during chewing. The food lump is crushed and exposed to the alkaline environment of enzymes that are found in saliva. The further digestion process continues in the acidic environment of the stomach. Bile breaks down fats, pancreatic enzymes process starch, fiber, muscle fibers. Subsequently, the chyme (food lump) undergoes final digestion in the intestinal juices.

In the case when the digestive system does not produce the required amount of certain enzymes and / or when the intestinal microflora is disturbed, the conversion of the antigen (allergen) into a substance neutral for the body is hampered and an allergic reaction occurs, which can manifest itself in the form of skin rashes or more serious and dangerous manifestations, such as swelling or difficulty breathing. That is why, in the complex therapy of atopic skin reactions, drugs can be prescribed that replenish enzyme deficiency, for example, the "Creon" remedy for atopic dermatitis.

Indications for use

Creon is used as a replacement therapy for enzymatic deficiency caused by the following diseases:

chronic course of pancreatitis;
condition after pancreatectomy;
condition after gastrectomy;
cystic fibrosis;
Schwachman-Diamond syndrome;
pancreatic cancer or other tumor causing obstruction of the pancreatic or bile duct;
condition after surgery with the imposition of a gastrointestinal anastomosis (for example, according to Billroth-II);
other diseases associated with a deficiency of pancreatic enzymes, including atopic dermatitis.

Reviews about the treatment of atopic dermatitis in children on the website of a well-known pediatrician dispelled my doubts about whether to use "Creon" for allergies in a child or not. I was worried that giving a child enzymes was evil, since then my own enzymes would stop being produced at all. It turns out that in reality everything is somewhat different and there is nothing wrong with the treatment with the use of the "Creon" remedy. There are practically no side effects (as in our case), and substances that can cause allergies are easily split into harmless ones and are absorbed by the body. I gave my daughter Creon for 14 days with meals. In combination with the use of antihistamines and capsules that improve the microflora in the intestines, the enzymes worked wonderfully. My daughter's stool became regular (although there used to be a tendency to constipation), the heaviness in the abdomen after eating stopped, rashes on the cheeks and in the folds of the arms, which began to redden and itch after 20 minutes after any meal, disappeared, although dry skin and slight peeling persist.

Method of administration and dosage

Cystic fibrosis

Lack of pancreatic function in various nosologies

Drugs that replenish enzyme deficiency are prescribed for atopic dermatitis in adults and children. It is worth noting that just taking enzymes to stop an allergic reaction and prevent the subsequent development of skin rashes may not be enough. As a rule, the treatment of atopic dermatitis involves a set of measures: the use of antihistamines, anti-inflammatory, hormonal, sedatives. Self-medication for atopic dermatitis is unacceptable!

Side effects

The incidence of side effects when taking Creon is comparable in frequency with the occurrence of adverse reactions when taking a placebo.

Rarely there are side effects from the gastrointestinal tract (stool disorders, abdominal pain, dyspeptic disorders) and allergic skin reactions.

Contraindications

Contraindication to the appointment of Creon is acute pancreatitis with pancreatic hyperfunction, intolerance to porcine pancreatin or any of the auxiliary components of the drug.

special instructions

Perhaps the use of Creon in children.

The absence of systemic effects allows the use of Creon in women during lactation.

Creon does not affect the rate of mental reactions and can be used in patients working with complex mechanisms or driving vehicles.

Allergy to Creon can be one of its side effects. It develops most often in those who cannot tolerate pig meat. In addition to enzymes, croeon also contains excipients - and they may be allergic. More often, Creon, on the contrary, helps to cope with allergies, as it removes toxic products formed during digestion.

Allergy to Creon - why and how it develops

Active active ingredient of Creon are pancreatic enzymes , which are obtained from the pancreas of pigs. Enzymes are catalytic proteins that regulate the processes of life and metabolism in organism. Pancreatic enzymes help digest the main food ingredients - proteins, fats and carbohydrates.

Excipients of Creon are macrogol 4000, hypromellose phthalate, dimethicone 1000, cetyl alcohol, triethyl citrate. The capsule shell contains gelatin, iron dye red oxide, iron dye yellow oxide, titanium dioxide, sodium lauryl sulfate. Any of these substances may be allergic.

How does it manifest

When you are allergic to a drug, in response to the ingress of an allergen, a number of biologically active substances are produced in the body, which cause an allergic reaction.

Allergy to Creon manifests itself in the form of a skin rash of a different nature, which is often accompanied by itching. The most common type of rash is urticaria, a rapidly growing red blister on the skin that can coalesce. Hives can develop quickly and disappear just as quickly. But this is not a harmless reaction. With its rapid growth, edema can go to the subcutaneous tissue and the soft tissues located under it. The danger is the transition of edema to the region of the larynx and vocal cords: the increased volume of soft tissues can block the access of air to the lungs. The appearance of allergies in the form of eating disorders is not excluded - nausea, vomiting, loose stools , bloating and abdominal pain.

If an allergy develops, you should stop taking Creon immediately and consult a doctor.

How Creon can help with allergic diseases

At the same time, the pancreas also has significant compensatory capabilities, so a person does not feel any changes. If allergic reactions continue for a long time, the function of the pancreas decreases and digestive disorders occur with the formation of toxic substances that increase the phenomenon of allergies.

Thus, with allergic diseases, changes in the pancreas almost always occur. That is why Creon is often prescribed as part of the complex treatment of allergic diseases.

Galina Romanenko

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