Ketanov Tablets: Instructions for use. Ketanov: Instructions for use, analogues, prices, prices in pharmacies of Russia Tablets Ketan Side effects

Ketanov tablets are a widely known painful agent. They also have anti-inflammatory and antipirelic activity. In what cases and how to apply Ketanov to tell the instruction.

With exacerbation of the articular disease, the acute flow of the inflammatory process or other bolt attacks can not do without an anesthesia. Most often in such cases are prescribed nonarcotic analgesics. They do not cause addiction, do not affect the psyche and do not apply irreparable harm to health. The strongest analgesic effects in a number of non-steroidal drugs have drugs manufactured by ketorolaca. These medicines are available under different trade names.

Pharmacological properties of the drug

The mechanism of action of ketanes, as well as most NSAIDs, is associated with non-selective inhibition of cyclooxygenase enzymes involved in the biosynthesis of prostanoids - highly active arachidonic acid metabolites. It is the excessive number of prostaglandins included in the prostanoid subclass, responsibly for the occurrence of pain, feverish state, the development of the inflammatory process.

There are 2 cyclooxygenase isoforms. COF-1 is constantly present in many tissues and organs, this enzyme forms the basal level of prostaglandins, protecting the gastric mucosa, providing the normal functioning of the liver, kidneys, genital organs regulating heart function and blood circulation. COG-2 begins to reinforce into peripheral tissues only under the action of damaging tissue factors initiating the inflammatory response in the focus.

All the side effects that arise - the result of the indiscriminate effects of ketans, expressed in the oppression of the activity of the constitutive enzyme COG-1. The therapeutic effect of Ketanov is due to the blocking of COX-2 and a decrease in the products of prostaglandins that are generated under the action of this type of enzyme.

According to the instructions of Ketanov, it provides:

  • analgesic effect - Reduces or completely stops pain, acting in a lesion focus, reducing the sensitivity of nerve endings to the effects of pain incentive. Ketanov is effective in relation to any types of pain, regardless of the cause of the occurrence, localization and degree of intensity. Can be used even with constant non-coming pain;
  • anti-inflammatory action - suppresses the inflammatory process, blocking the production of cellular inflammation modulators, reducing vascular permeability, normalizing blood circulation in the damage zone. The result becomes the weakening of the expression of the inflammatory phenomenon: removal of swelling, focal hyperemia, local increase in tissue temperature, elimination of soreness, swelling of the joint and restoring disturbed functions. Compared to the anesthetic effect of ketanov, its anti-inflammatory activity is less pronounced;
  • antipyretic effect - normalizes the pathologically elevated body temperature, reducing the concentration of prostaglandins and returning to normal indicators displaced with pyrogen substances to a higher level of the installation point of thermal homeostasis. Ketanov has a weak antipyretic activity.

Composition, form of release

The Ketan Registration Card holder is the Indian Pharmaceutical Firm Ranbaxi Laboratories Limited. The Russian market of Ketanov comes in 2 dosage forms - tablets and injectable solution. The active ingredient is represented by Ketorolak with troometamine (synonym for Ketorolak Trometamol). In 1 tablet contains 10 mg of active substance.

Tablets are a circular two-way form, have a film coating, on the one hand the letter KVT is squeezed. Paired in plastic blisters for 10 pcs., It may be invested in an individual pack: 1, 2, 3 or 10 such blister packs.

The instruction contains a list of auxiliary ingredients:

  • Microcrystalline cellulose (MCC), modified corn starch - tablet fillers;
  • magnesium stearate - lubricant;
  • Colloidal particles of anhydrous silicon dioxide - enterosorbent, providing the rapid removal of toxins.

Film shell composition:

  • Hydroxypropylmethylcellulose (receiving) - regulates the solubility of the composition;
  • Macroogol 400 is a stabilizer of the composition;
  • Purified Talc - sliding substance;
  • Titanium dioxide - color corrigent.

How can Ketanov acts

The features of the chemical structure of the active component of the ketanes - derivative of acetic acid are allowed to include the drug to the clinical and pharmacological group comprising an NSAID with a pronounced painkillers. According to the effect, the effect is comparable to the effects of opioid analgesics - morphinea morphine-containing mixtures. At the same time, the drug is deprived of undesirable ACCLITI and sedative properties, does not affect platelet levels and their functional activity does not lead to changes in the heart muscle.

Ketanov is characterized by speed - the decrease in pain is permanently after 40-60 minutes after taking a tablet, complete anesthesia occurs after 2 hours. The effect is saved to 7 hours. To minimize the risk of developing adverse reactions provoked by the non-selective action of ketorolac, the medicine must be made in minimal effective doses limited to the crossed course.

When appointing ketan tablets and the choice of dosing mode, the processes occurring with the drug after its introduction to the body are taken into account.

Pharmacokinetic parameters having clinical significance are given in the instructions.:

  • Suction: When orally intake, Ketorolac is almost completely absorbed from the intestine (the shell protects the composition from rapid dissolution and premature action, thereby protecting the walls of the stomach). Ketanov is characterized by maximum biological accessibility reaching 80-100%. Peak plasma concentrations are fixed in 40-50 minutes. The fact of meals for the degree of absorption of ketorolac does not affect, but the presence of fatty food slows down to 1 hour the suction process and, accordingly, reduces the rate of the onset of therapeutic action. The equilibrium concentration of the bearer of the blood plasma reaches a regular, 4-time reception. With longer dosing, these values \u200b\u200bdo not change.
  • Distribution: In a free form in systemic blood flow, only less than 1% of the received drug is located, the remaining amount circulates in the associated state as a complex with plasma proteins. Ketorolac is widely distributed between the tissues and organs, easily penetrates the lesion focus, enters the articular bags, articulation cavities, synovial membranes. Overcomes the placental barrier, excreted into breast milk.
  • Metabolism: The chemical structure of the medicinal substance is partially changing under the influence of hepatic enzymes. The resulting metabolites pharmacological activity do not possess.
  • Excretion: Metabolites (40%) and the remains of otanov leave the body mainly with the urine (more than 90%), in a small part with the carte masses. The concentration of the substance is dropped twice in 4-6 hours after oral or parenteral (intramuscular) input. At high school, as well as patients with a deterioration in kidney performance, the half-life indicators increase to 10-14 hours, which increases the toxicity of the drug, so this category of patients requires a dose correction.

Indications for reception

The reason for the relapse and progression of the disease of the ketanov does not affect, this is a means of symptomatic therapy, intended for the treatment of manifestations of the disease. As a potent analgesic of nonsteroidal action, the drug can only be used with short-term pains - strong or moderate intensity or in cases where the use of other NSAIDs turned out to be ineffective. Use the drug to remove chronic pain is not recommended.


According to the instructions in the indication for receiving Ketanov tablets is:

Instructions for use

Depending on the degree of severity of the inflammatory process or pain, tablets can be taken once or regularly until completely relieved pain. Single dosage - 1 tablet. In the case of ceta treatment, the recommended multiplicity of reception is 3-4 times, this is not more than 40 mg of ketorolac. Between repeated receptions, it is desirable to withstand the maximum long interval. The duration of use should not exceed 5 days.

The instruction instructs certain rules for receiving tablets:

  • Do not disturb the protective shell, swallow the whole, drinking sufficient water.
  • To reduce the risk of damage to the gastric mucosa, take together with meals or immediately after meals.
  • If the pain is insufficient and need a quick effect - it is permissible to take a tablet on an empty stomach.
  • Control symptoms if the pain weakly weakened, then it is not recommended to accept an excess pill.
  • With strong pains with the permission of the doctor, the ketan tablets are allowed to combine with opioid analgesics.

Failure to comply with the established dosages is fraught with poisoning.

Overdose manifests usually by pain in the abdominal cavity, vomit, dizziness, slow motion, to sleep or excitement. Subsequently, damage to the inner shell tissue of any digestive tract, a disorder of acid-alkaline equilibrium, a failure of the kidneys can be diagnosed.

Having found any of the listed symptoms, you should complete the reception and urgently remove the remnants of the drug from the body, flushing the stomach, ensuring a sharp increase in the diurea, making activated carbon. Cleansing the dialysis method to sufficient effect will not give. Increased caution is required to abide by patients with liver, kidney, heart, chronic active hepatitis, bronchial asthma, nose or nasophal polyps and after 65 years.

According to the instructions of Ketanov, contraindicated to the reception in the case of:

  • individual intolerance to the components of the tablets, Ketorolak, other NSAIDs;
  • aspirin triad;
  • dehydration or reduction of circulating blood (hypovolemia);
  • diseases of the liver or gastrointestinal bodies in the phases of exacerbation;
  • hypocoagulation, active bleeding, impaired hematopoietic function, hemorrhagic stroke;
  • Children's or adolescent age - 0-16 years;
  • tooling a child or breastfeeding.

Side effects

The instruction informs about a number of unwanted phenomena, capable of developing in the course of treatment with potent analgesic otanov. Especially this contributes to the reception of high doses and pills abuse.

The following side effects appear most often:

  • Catching pains in the stomach area or pelvic area, constipation either diarrhea, vomiting, gases accumulation in the intestine, feeling thirst, stomatitis;
  • Pressure jump, arrhythmia, temporary loss of consciousness, headache, drowsiness, mood swings, vertigo, loss of taste perception;
  • violation of visual, auditory, respiratory function;
  • problems with urination, azotemia, blood in the urine, kidney pain or swelling;
  • various types of bleeding, change in blood pattern;
  • Increased sweating, heat, rash on the skin, purple, itching.

Attention!

During the treatment of ketans, the reception of alcohol is prohibited, the driving of a car or the performance of other works requiring the speed of reaction and concentration is not recommended. Ketanov is able to influence the effects of many drugs or change its characteristics when combined. To avoid adverse drug interactions, about all cases of consistent or simultaneous reception of other drugs, you must notify the doctor. Only a specialist will be able to correctly recalculate the administered doses.

The cost of the drug, analogues

Ketanov tablets - prescription drug. In the factory package, in a darkened place and at temperatures up to 25 degrees are stored 3 years. You can buy a medicine in any pharmacy network.

The cost of Tablets produced by Romania is:

  • 20 pcs. - 50-70 rubles;
  • 100 pieces. - 220-250 rubles.

Ketan's analogues are other NSAIDs manufactured by ketoprofen, sodium diclofenac or indomethacin. The closest properties have preparations, including the same active substance, are pills:

All changes in replacement should be coordinated with the doctor. Powerful painkillers have a lot of contraindications, their incorrect reception is able to lead to serious complications, therefore it is unacceptable to engage in self-treatment.

Ketanov belongs to the group of strong nonarcotic analgesics. More precisely, to the group (non-steroidal anti-inflammatory means). The effect of small and large doses of the drug significantly removes pain syndrome.

CETANS is produced in three forms:

  1. The solution for intramuscular injections in ampoules, 1 ml volume, with a containing substance content of 30 ml / ml. Fossing ampoules in boxes with instructions for use, 10 pcs.
  2. Tablets for reception inside containing 10 mg of the active component, 10 or 100 pieces in the box.
  3. Ketanov MD - relatively new type of medication - pills for resorption.

The medicine contains the active substance of Ketorolaca Trometamine.

Manufacturer Ranbaxy Laboratories, Ltd. (India) In Candle, Mazi and Gel Ketanov does not release. For outdoor application, the doctor can assign a group analogue, NSAIDs containing.

Properties

The mechanism of action of Ketorolak is similar to the entire NSAID substance group. Ketorolak suppresses the production of COF (cyclooxygenase) and further prostaglandins. If this is not done, a chain of biochemical reactions is launched on an irritating factor, as a result of which inflammation is formed in tissues, pain and fever.

Ketanov has pronounced painkillers. The relief of inflammation and a decrease in body temperature during fever appear to a lesser extent.

Prescription leave.

Analogs

  • Vatorlak;
  • Dolk;
  • Ketalgin;
  • Ketofril;
  • Matrolly VM.

Video: Ketanov

Content

For pain relief, doctors are often prescribed by the drug Ketanov - instructions for use indicating that it relieves inflammation, intended for persons over the age of 16 years. Tablets are accepted to relieve pain - dental head, menstrual, the solution is used intramuscularly. Familiarize yourself with the recommendations for the use and contraindications of the medication to be treated correctly.

Anesthetic ketanov

According to the pharmacological classification, the drug of ketans refers to non-steroidal drugs with antlegum and anti-inflammatory effects. This means that it will buy pain syndromes, relieves inflammation. The active intensity of the medication is Ketorolaca Trometamine, which has a pronounced analgesic effect.

Composition and form of release

Ketanes are produced in the form of tablets and injection solutions. The detailed composition of each drug is given further:

Pills

Description

Shell-covered, round

Transparent colorless pale yellow liquid

The concentration of active substance, mg

Starch corn, microcrystalline cellulose, water, macrogol, silicon dioxide, talc, hydroxypropylmethylcellulose, magnesium stearate

Sodium chloride, alcohol, water, sodium Edetat, sodium hydroxide, hydrochloric acid

Packaging

10, 20 or 100 pcs. in pack

5 or 10 ampoules 1 ml in pack

Pharmacological properties

Non-steroidal anti-inflammatory agent (NSAID) refers to the pyrrolized-carboxylic acid derivative, has an analgesic, anti-inflammatory and moderate antipyretic effect, stimulates opioid receptors. The mechanism of work is associated with the oppression of the enzyme the metabolism of arachidonic acid, which is the predecessor of prostaglandins. These substances cause inflammation, pain and fever.

Oral administration of the drug allows you to get the active substance with the walls of the stomach and intestines and reach the maximum concentration in the blood plasma in 45 minutes (in parenteral administration similar time). Meal does not affect the absorption of the medication, it binds to the proteins by 99%. An active substance is excreted after 4-10 hours with urine, intestines. If the kidney function is violated or in the elderly, the output time increases.

Indications for the use of Ketanov

The instructions for use said about the testimony for the use of the drug - this is a short-term relief of moderate and strong pains of the next origin:

  • postoperative bleeding (after abdominal, orthopedic, gynecological operations);
  • when dislocate, fractures, damage to soft tissues;
  • toothpick, after surgical interventions from the dentist;
  • postpartum period, oncology;
  • osteoarthrosis, Ishialia;
  • not applicable in chronic pains.

Ketanov from abdominal pain

As in the case of any other pain, Ketanov helps with abdominal pain, but according to the reviews of doctors, it is not recommended to do this. The reason for the negative effect of the drug on the mucous membrane of the digestive tract is becoming. If the abdominal pain is caused by the pathologies of the internal organs, the use of the drug is prohibited, since the relief of the syndrome will postpone a visit to the doctor, will increase the risk of complications. You can use tablets if the pain is short-term, arose after the operation.

Ketanov with menstruation pain

Most women have menstruation pains are caused by a spastic reduction in the uterus, which cause prostaglandins. If the patient has no problems with the sexual sphere, the bend of uterus or hormonal disorders, otanov effectively copes with pain, blocking the production of substances that impede the normal blood movement along the vessels of the genital organs.

For dental pain

The active component of Ketorolac is known for a strong painkillers due to the obstacle to the production of prostaglandins. Finding inside, it acts systemically, and not just a toothache. The drug helps with a strong pain syndrome, which passes in 35 minutes, and the action lasts up to seven hours. Due to the antipyretic effect, analgesic can be used with strong inflammation from pulpitis or periodontitis.

Method of application and dosage

According to the instructions for use, the method of use and dosage of the drug depends on the form of the issue and individual characteristics of the patient, plus from the severity of the pain symptom. The ampumery solution is applied parenterally, injected with intramuscular injections. Tablets are designed for oral intake. Dosage, course and multiplicity determines the doctor, you should not do this yourself.

Other dose of Ketanov in ampoules is 10-30 mg with an introduction interval every 4-6 hours. The maximum duration of the solution is two days. The maximum daily dosage is 90 mg, for patients with a body weight to 50 kg, with violations of the kidney function or over the age of 65 years - 60 mg. The solution is entered only in a hospital, begins to act in half an hour, the maximum effect reaches 1.5 hours, and the anesthesia lasts up to six hours. In the initial postoperative period, the solution is introduced every two hours.

Tablets Ketanov

For intake, the adult shows 10 mg of tablets every 4-6 hours, with acute pronounced pain syndrome of 20 mg every 3-4 hours. The maximum daily dose of the tablet form is 90 mg (8 tablets), for elderly patients, with a body weight up to 50 kg or patients with impaired kidney function - 60 mg. The tablets are swallowed entirely, do not frame, do not chew, 100 ml of pure water ished.

The reception is desirable to exercise after eating so as not to harm the mucous membrane of the gastrointestinal tract. If the food was abundant and fat, the effect will slow down. For the best possible relief pain, it is recommended to drink tablets before meals. Doctors recommend taking tablets on schedule, on the day of combination with a solution cannot be made more than 30 mg. The duration of continuous treatment is 5-7 days.

special instructions

In the application instructions, it is useful to explore the section of special instructions, from where the patient will turn around a lot of new:

  • caution preparation is prescribed to patients in violation of platelet function, liver, chronic heart failure, high pressure, gastrointestinal erosions, risk of ulcers;
  • after resection of the prostate gland, tonsonyctomy, plastic operations require careful homeostasis, the poet the agent is prescribed under medical control;
  • when a rash appears on the skin, the symptoms of the liver damage to the medication should be canceled;
  • if drowsiness, dizziness appears during therapy, it is recommended to refrain from the management of machines and mechanisms, because psychomotor functions slow down;
  • the drug is prohibited by pregnant women, mothers when lactation, children, with supporting anesthesia in obstetric practice due to an increase in the duration of the generic period, inhibition of the reduction of the uterus and the blood flow of the fetus;
  • against the background of regular reception, it is recommended to take blood test analysis once a month and pass the coagulogram to not have problems with blood coagulation.

How often can you drink ketanov

According to the instructions for use, the ketanes are used every 4-6 hours of 1 tablet or 10-30 mg of solution. Do not think that then 6-8 tablets per day. You can maximize 3-4 tablets or a daily dose of 90 mg.The duration of the reception of the solution should not exceed two days, and the tableted form of the medication is a week, because it causes negative reactions.

Ketanov Children

Due to the strong influence on the children's body, the drug is contraindicated to children and adolescents under the age of 16. With breastfeeding, it is recommended to cancel therapy or, if it is impossible, stop lactation and resume it after the doctor's permission so that the newborn does not receive negative consequences for its health. Before use, always consult your doctor.

Medicinal interaction

The instructions for use indicated on the drug interaction of tablets and injections of Ketanov with other drugs:

  • the combination with other NSAIDs can lead to increased side effects;
  • Pentoxifillalin, anticoagulants, heparin strengthen the risk of bleeding;
  • aCE inhibitors increase the risk of renal failure;
  • Slobalucid increases the output period of medication from the body4
  • lithium preparations slow down the kidney clearance of ketorolac and metal, increase its concentration in plasma;
  • Ketanov reduces the rugged effect of furosemide;
  • when combined with opioid analgesics or narcotic analgesics (morphine) requires a dose correction.

Side effects and overdose

From the instructions, you can learn side effects of ketanov in the form of injections and tablets that are manifested in the following factors:

  • bradycardia, a change in blood pressure, fainting, rapid heartbeat;
  • nausea, abdominal pain, diarrhea, constipation, meteorism, vomiting;
  • dry mouth, thirst, stomatitis, gastritis, erosion, ulcer;
  • headaches, anxiety, drowsiness, paresthesia;
  • depression, sleep disorders, vision, taste, movements, respiration, urination;
  • bleeding from nose, hematuria, anemia, swelling;
  • skin itching, rash, dermatitis, urticaria, allergic reactions, Malgia;
  • bronchospasm, anaphyactic shock, fever.

Contraindications

For receiving Ketanov there are certain limitations. This is contraindications in which drug use will cause negative phenomena:

  • erosion, stomach ulcers and a 12-rosewood in the aggravation stage;
  • gastrointestinal bleeding or suspicion of it;
  • hemorrhage hemorrhage;
  • blood coagulation disorders;
  • hemorrhagic diathesis;
  • incomplete hemostasis;
  • aspirin triad;
  • renal, liver failure;
  • polyps in the nasal cavity;
  • bronchial asthma;
  • age up to 16 years;
  • pregnancy, lactation;
  • increased sensitivity to components, acetylsalicylic acid or other NSAIDs;
  • birth.

Terms for sale and storage

Both forms of release of Ketanov can be purchased by prescription. Preparations are stored at temperatures up to 25 degrees for three years for a solution and five for tablets.

Analogs

On the shelves of Russian pharmacies you can meet synonyms and Ketanov analogues. First include drugs whose composition is completely identical, the active substance is the same and is at the same concentration. Substitutes include similar means of therapeutic effect. Popular analogues are:

  • tablets Ketorol, Ketorolak, Ketofril, Dolk, paracetamol;
  • solution for injections of ketorolac, dolomin, ketalgin, ketorol.

What is stronger - Ketorol or Ketanov

It is impossible to argue that Ketherol or Ketanov. They contain the same active substance Ketorolac. Both drugs are produced in the form of tablets and a solution, but Ketorod has a gel form. The means belong to different Indian companies, differ in price - ketorol is cheaper by about 25%. The choice of the drug from these two remains behind the doctor or patient.

Price Ketanova

You can buy ketanov through the pharmacy network or the Internet. The cost of the drug line depends on the form of the release, the number of tablets in the package and trading charge. Exemplary prices in Moscow and St. Petersburg will amount to:

Video

Ketanov is an excellent anesthetic drug, which is prescribed as symptomatic therapy and for complex treatment. A medication is produced in the form of tablets and a solution for injection. We will tell you what doses must be used to remove the pain syndrome and describe all the side effects of the drug.

Doctors prescribe injections or pills to remove severe pain. The drug is great for short-term use. Ketanov can cope with such types of pain syndromes:

  1. Moderate or severe pain after a serious operation;
  2. Pain due to gynecological diseases;
  3. Uncomfortable sensations after an orthopedic diagnosis;
  4. For removing urological pain;
  5. As symptomatic therapy after visiting the dentist;
  6. With acute muscle injury;
  7. With fractures and tissue breaks;
  8. Removal of pain when dislocation and strong tension.

In addition, doctors are prescribed Ketanov to remove the attack of short-term pain in such cases:

  • After canceling drug intake;
  • Fighting tootham;
  • With caries and pulpita;
  • In case of pericoronitis;
  • With colic in the kidneys. Appointed in a complex with spasmolitics;
  • Removes pain after childbirth;
  • When otitis;
  • To remove the attack of Ishiagia;
  • At the time of fibromyalgia;
  • Spasms with osteoarthritis;
  • Syndrome stopping at the moment of radiculitis;
  • Removal of back pain during osteochondrosis;
  • In pathology in tissues and muscles.

For each case, the doctor prescribes a certain dosage of Ketanov. Therefore, it is important to consult with the doctor and pass the inspection before taking medication. Incorrect dose may not remove pain or cause side effects.

How to use tablets?

Usually, for the removal of a strong pain, the doctor is assigned 1 tablet every 4 hours. This is 10 mg of the active substance. The reception rate of Ketanov should not last more than 7 days. Some patients need to be prescribed a dosage below:

  1. Older people over 65;
  2. Patients with weight less than 50 kg;
  3. People with the problems of the liver and kidneys.

Dosage of the drug in the form of a solution

Ketanes in the form of an injection solution are prescribed intramuscularly. To remove the first attack of pain, it is necessary to introduce 10 mg of the drug. After 5 hours, the dosage should rise to 30 mg. Control the injection of the medicine should have a doctor.

Maximum dose of Ketanov per day is no more than 90 mg. Elderly patients need to introduce no more than 60 mg of medication.

Making injections with drug allowed 2 days to relieve pain. After that, the patient can take otanov in tablets for another 5-7 days before the full disappearance of pain symptoms.

After the first injection, the unpleasant pain passes after 30 minutes. Full anesthesia will occur after 2 hours. The doctor must definitely change the dosage based on the patient's diagnosis and its general condition. To reduce the likelihood of side effects, you should not prescribe too high a dose.

Contraindications for reception

For some patients, it is strictly forbidden to use ketanes in the form of anesthetic. The drug will not remove an unpleasant symptom and only harm health. Here in what cases doctors do not recommend taking medication:

  • Allergies to any component in the composition of tablets or mortar;
  • If the patient opened an active ulcer;
  • When bleeding in the stomach;
  • At the moment of a peptic disease;
  • Dangerous at bronchial asthma;
  • Not appointed with angioedema edema;
  • With ritin;
  • Dangerous at urban;
  • Not applied before the operation and at the time of manipulation with vessels;
  • Due to insufficiency in the work of the heart;
  • In the occurrence of polyps in the nose;
  • In case of bronchospasm;

  • Not appointed with the swelling of the quinque;
  • It is dangerous for patients after surgery, which previously had frequent bleeding;
  • Not prescribed when fighting in pregnant women;
  • When using other painkillers;
  • Dangerous in hemorrhagic diathesis;
  • If the patient has blood clotting disorders.

The reception of Ketanov in such cases may cause severe complications and aggravation of pain syndrome. It is imperative to consult with the doctor before taking this anesthetic and tell the doctor about all past diagnoses. It is best to undergo a diagnosis that will help identify hidden disorders in the body.

Using the drug during pregnancy

It is also not recommended to take a medicine when feeding a baby with breasts. Through the milk, the composition of the substance can get into the toddler's body and cause an allergic reaction. If a woman has started strong pain and the doctor appointed a reception of Ketanov, then it is necessary to immediately stop breastfeeding.

Interaction with other drugs

If you take otanov in parallel with other medicines, it can cause complication or lead to a decrease in an anesthetic effect. Here is a list of basic interactions to pay attention to:

  1. It is forbidden to take warfarin along with Ketanov. Otherwise, an anesthetic effect will decrease to 97 percent. It is also not worth drinking digoxin, heparit and other salicylates;
  2. Use with acetylsalicylic acid. It is not recommended to combine two drugs, since there are risks of the occurrence of side effects;
  3. Application of probelocide. With parallel reception, the action of Ketanova is reduced. Doctors do not recommend combining these drugs;
  4. Taking cyclosporin. May lead to nephrotoxic side effects. Not used with Ketanov;
  5. Parallel use of SPEPENTIFILIN. This leads to the development of hazardous hemorrhage;
  6. Use with myfepriston. The effect of this drug will completely disappear, if you start taking ketanov;
  7. It is prohibited by parallel use of drugs with lithium;
  8. Use of anticoagulants. If you take them together with Ketanov, it leads to the risk of bleeding. Simultaneous intake is categorically contraindicated.

If it can take the above-described drugs in parallel, this can lead to dangerous side effects and deterioration of the overall state. It is necessary to inform you to inform the doctor what medicines you are currently accepting so that it can correct therapy.

Overdose drug

When taking too much dose of Ketanov, such unpleasant symptoms may begin:

  • Reaction slows down;
  • A strong headache appears;
  • Sense of sleepiness and lethargy;
  • Nausea and vomiting;
  • Severe abdominal pains;
  • When taking too much dose - bleeding in the stomach;
  • Attacks of arterial hypertension;
  • The emergence of renal failure;
  • In extreme cases - problems with breathing, convulsions and coma.

Doctors reported that Ketanov with a long-term reception in a high dose, led to a fatal outcome. Therefore, it is important at the first signs of side effects immediately apply to the hospital.

Doctors must appoint symptomatic therapy for the patient. Not later than 4 hours after an overdose you need to cause vomiting or take activated coal. The required dose is 100 grams for an adult patient. Doctors often prescribe osmotic drugs to remove symptoms.

With one-time overdose, the tool begins pain in the stomach and nausea. Usually such symptoms take place immediately after the cessation of Ketanov.

If you ignore unpleasant symptoms and not consult a doctor, the reception of large doses can lead to dangerous complications.

Side effects of the drug

Ketanov has some side effects that the doctor should warn. Typically, symptoms arise due to the reception of a large dose or intolerance to the organism of the medication.

Where do you occur?Side effects
Such complications may begin in digestionAttack of nausea and vomiting;
The emergence of anorexia;
Uncomfortable sensations in the stomach;
Pain and spasms in the stomach;
The patient feels a change in the mouth in the mouth;
Ulcers in the area of \u200b\u200bthe stomach;
Strong bleeding, which can lead to a fatal outcome. There are elderly patients;
Diarrhea attack;
A feeling of dryness in the mouth;
Severe thirst;
The occurrence of meteorism and constipation;
Attacks of pancreatitis;
Feeling of overcrowding in the stomach;
The emergence of the initial stage of gastritis;
Strong belching;
Manifestation of colitis and crown disease;
The emergence of esophagitis.
These side effects occur in the liverViolates the work of the body;
Manifestation of renal failure;
In rare cases, jaundice arises;
Attacks of raising hepatic enzymes;
The emergence of hepatitis and hepatomegaly.
In the nervous system you can observe such complicationsFatigue and sense of drowsiness;
Memory and concentration problems;
Strong headaches;
Attacks anxiety and panic;
Begins to spin the head;
Insomnia manifestation;
Overexcitation of the body;
The patient feels ailment;
There is stress and strong irritability;
A man sees unusual dreams at night;
Disorientation occurs in space;
Fever and convulsions begins;
Changes of mood and anxiety;
Harsh hallucinations;
A man can faint;
Manifestation of psychosis.
In the work of the cardiac system, such side effects can be notedBlood tides to the head ;;
Pallitude of the skin;
The heart begins to beat more often;
The occurrence of palitation;
Severe pain in the chest zone;
Swelling on the skin;
Insufficiency in the work of the heart;
Development of arterial complications;
In extreme cases - myocardial infarction or stroke attack.
In the circulatory system such side effectsManifestation of aplastic anemia;
Purple appearance;
Attacks of leukopenia;
Strong agranulocytosis;
The occurrence of thrombocytopenia;
Neutropenia.
In bronchi, the drug causes such complicationsAttacks of bronchospasm;
Severe shortness of breath;
Swelling in the lungs and larynx;
Bouts of bronchial asthma;
Exacerbation of the lung disease.
Side effects in the ureteria systemUrban frequency increases;
Attacks of nephrotic syndrome;
Delays when going to the toilet;
Increased crotinine in the urine;
The occurrence of papillary necrosis;
Severe pain in the lower back region;
Renal failure;
Attacks of hematuria.
Such complications may occur on the skinSevere rash;
Dermatitis;
The skin begins to peel;
Almonds increase;
Pictures of photosensitization.
In the immune system allocate such complicationsAllergy to the composition of the drug;
Anaphylactoid reactions that can lead to a fatal outcome;
Skin color on the face may change;
Urban appears on the body;
Torments strong itching;
Swell the eyelids in the patient.
In the senses, such side effects manifestReduction of hearing;
Tinnitus;
Drop view;
The occurrence of neuritis in the eye nerve;
Fucetitude view.
Other side effectsThe patient's body begins to sweat much;
Attacks of Malgia;
Changing the color of the skin at the injection site;
Swelling of face and hands;
Improving body weight;
Strong fever;
There is a chill in the body.

Features of the use of drug

In order for Ketanov to remove severe pain and did not harm the health of the body, it is necessary to know some rules for reception. Doctors give such useful tips:

  1. To reduce the likelihood of side effects, the doctor must first appoint a minimal dose of Ketanov. It is better to take the drug for just a couple of days, since long therapy may cause complications in some organs;
  2. After the injection is injected, the pain passes only after 30 minutes. Therefore, you need to be patient and not to take several painkillers at once. Otherwise the dangerous interaction of drugs will begin;
  3. Do not drink tablets more than 5 days in a row;
  4. If the patient has problems with kidneys and liver, it is advisable to minimize the dose and be under the control of the doctor. The specialist is obliged to regularly control the diuresis and the work of the kidneys;
  5. For women who cannot be pregnant for long, it is necessary to refuse to receive Ketanov;
  6. If the patient has a Crohn's disease, he needs to be cautiously prescribed a drug in tablets with great care;
  7. Regular control is needed for patients with a weak heart. Better at the time of therapy to be in the hospital next to the attending physician.

Rules for storing medicine

The drug ketanov must be kept in a dark place at a temperature not higher than 25 degrees. It is important that children do not have access to medicine. The shelf life of Ketanov - no more than 3 years from the moment of manufacture. In no case do not take the medicine after the expiration of this time.

Analogs of the drug

The doctor may write a patient from pain another medicine. It will be similar to Ketanov according to the method. Here is a list of all similar preparations:


Each tool has its own contraindications and a number of side effects. It is necessary to study this information and carefully read the instructions for use.

Price for medicine

You can buy a drug of Ketanov in each pharmacy without a doctor's recipe. Cost for medicine in different forms:

  1. Ketanov in the form of 10 mg tablets - from 67 to 73 rubles per 20 pieces;
  2. Ketanov in pills of 10 mg - from 200-230 rubles per 100 pieces;
  3. Ketanov in the form of a solution for injection - from 113 to 125 rubles for 10 ampoules.

Ketanov refers to analgesic drugs. In addition to relieving pain, it also eliminates inflammation and has a moderate antipyretic effect.

According to analgesic effect, this means is comparable to morphine and much more efficiently other non-steroidal anti-inflammatory drugs. Moreover, it does not have the danger of sedative impact and does not produce sense of dependence.

Data from instructions for use

Produced forms

Ketanov is produced in tablets and ampoules that should be kept in a pre-humid place with a temperature not higher than 25 ° C. The drug has a three-year shelf life.

The tablet shape of the drug is a carton pack with blisters (each 10 pcs.), And their number ranges from 1 to 10. Tablets have a round, biconvex form. Covered with a white shell with engraving on one side of KVT.

The composition of one tablet includes thrometamine ketorolaca (10 mg).

Auxiliary substances serve:

  • corn starch,
  • colloidal silicon dioxide
  • magnesium stearate.

The film shell consists of:

  • hydroxypropylmethylcellulose,
  • makroogol 400,
  • purified talca
  • titanium dioxide
  • purified water.

1 ml ampoules are included in the cardboard kidney 5 (10) pcs. Injection solution has a pale yellow color or colorless transparent.

In 1 ml of an intramuscular solution, a troomethamine ketorolac (30 mg) is contained.

As auxiliary substances used:

  • sodium chloride,
  • edetat Dinataria,
  • sodium hydroxide,
  • water.

Who prescribe a tool

The main purpose of the drug is the removal of medium or strong painful syndrome of any origin, including oncological diseases, injuries and postoperative period. How practically effective cannas can be found from reviews at the end of the text.

Ketanov is effective for relieving pain accompanying:

  • osteochondrosis
  • radiculitis,
  • osteoarthritis,
  • ears, fractures or dislocation
  • pulpitis,
  • pericoronite
  • oncological disease
  • neuralgia
  • ishiygia,
  • otitis,
  • hepatic (renal) colic,
  • in the head of the head
  • menses.

The drug eliminates postoperative pains in areas:

  • general surgery
  • gynecology
  • orthopedics
  • urology
  • otolaryngology,
  • dentistry.

Who should not use ketanov

As contraindications, it is important to keep in mind:

  • aggravated sensitivity to parts of the drug, manifested in the form of bronchospasm, "aspirin asthma", angioedema edema, dehydration;
  • ulcerative destruction of the stomach and intestines in the stages of exacerbation;
  • reduced blood coagulation and bleeding disorders;
  • renal (liver) failure;
  • hemorrhagic stroke;
  • state of pregnancy, childbirth, breastfeeding;
  • the age of children is not older than 16 years;
  • therapy of chronic diseases.

Care

The drug should be used very carefully at:

  • cholecystitis
  • asthma bronchial
  • chronic heart failure
  • arterial hypertension
  • hepatitis in the active phase
  • violations of kidney functions,
  • system Red Volcanka,
  • sepsis
  • old age (after 65 years),
  • nasopharynx polyps.

Other significant information

On possible side manifestations

They may arise in the form:

  • gastralgia, diarrhea, constipation, meteorism and other disorders of the digestive system;
  • pain in the lower back, renal failure, edema of renal origin, jade;
  • stall in the ears, lowering hearing and vision;
  • dysfots, difficulty breathing, bronchospasm, larynx swelling, rhinitis;
  • dizziness, headache, drowsiness, depression;
  • raising blood pressure;
  • anemia, leukopenia;
  • bleeding (nose, etc.);
  • skin rash, urticaria.

In addition to these consequences, there may be other side effects, such as swelling of various parts of the body, increased sweating.

Questions of interaction with other medicines

The sharing of the tablet form of Ketanov with other drugs can give an unexpected result, for example:

  1. Eating along with aspirin or other non-steroidal anti-inflammatory agent can provoke a stomach ulcer or gastrointestinal bleeding.
  2. Combination with paracetamol can lead to nephrotoxicity (kidney damage), with methotrexate - to nephro- and hepatotoxicity.
  3. Adding indirect anticoagulants, trocharmedics, heparin increases the risk of bleeding.
  4. The combination with diuretics, hypotensive, analgesic means of their effect decreases.
  5. If you take oral hypoglycemic drugs and insulin in parallel, their action rises. Therefore, it is necessary to recalculate the dose.

Mixing in one syringe solution for injections with morphine sulfate, hydroxyzine will cause precipitate. Ketanov has pharmaceutical incompatibility with lithium preparations and tramadol in solution.

Injection solution is combined with solutions:

  • physiological
  • Ringer
  • dextrose 5%,
  • infusion.

Methods of use

After intramuscular administration, an anesthetic effect begins after half an hour. Receiving tablets inside gives this effect in an hour. The maximum result comes after one or two hours.

Receive tablets

Depending on the level of pain, tablets are taken inward once or repeatedly. The dose is 10 mg. Re-admission implies the same dosage that needs to be taken no more than 4 times a day, which depends on the degree of pain. The greatest daily dose is 40 mg.

The course of treatment is a maximum of 5 days.

Introduction of the solution

The minimum effective doses are selected on the basis of the degree of pain and individual human reaction.

One-time dose of single intramuscular injection solution is:

  • persons younger than 65 years from 10 to 30 mg (dose depends on the degree of pain);
  • after 65 years, 10-15 mg is prescribed with impaired kidney functions.

For multiple administration:

  • persons under 65 years old first 10-30 mg, further every 4 or 6 hours in the same dose;
  • after 65 years and with impaired kidney functions - every 4-6 hours 10-15 mg.

The longest time of treatment is 5 days.

Transitional doses

When changing intramuscular administration, the means on the tablet reception total dose for days should not exceed:

  • 90 mg for persons under 65 years old
  • 60 mg after 65 years or in disruption of kidney functions.

On the day of the transition, the amount of medication in tablets should not be higher than 30 mg.

What else is important to know

The price and analogues

In Russian pharmacy chains of Ketanov in tablets, there is an average of 40-50 rubles. (20 pcs.) And 240-250 rubles. (100 pieces.). In ampoules 10 pcs. Stand 112-115 rubles.

In Ukrainian pharmacies, these prices are respectively equal: 18, 185, 106 UAH.

Analogues that can be used instead of Ketanov:

  • Ketorol
  • Emodol,
  • Ketolong Darnitsa,
  • Ketalgin,
  • Ketonort
  • Novalket Health,
  • Fanigan,
  • Diclot
  • Diclac
  • ASEFIL,
  • Flap
  • Diax
  • Aeral
  • Ariral.