Lactofiltrum – medicine combined action, sorbent acting in the intestinal lumen, and active substance from the group of prebiotics. The sorbing (suction) effect is manifested due to the accumulation of toxic compounds on the surface of the sorbent. The prebiotic effect is expressed in stimulating the growth of beneficial intestinal flora and restoring the balance of natural microorganisms. According to the instructions for use, lactofiltrum as an enterosorbent that normalizes intestinal microflora is prescribed for both adults and children.
Composition of the drug and pharmacological action
The clinical effect of taking it is achieved due to active ingredients as part of Lactofiltrum:
- hydrolytic lingin, a product of hydrolysis of natural wood, which provides absorption and some disinfection effect in the intestinal cavity. Lingin is not absorbed through the walls and does not enter the systemic circulation, being limited to local exposure. This active substance binds, collects and removes most toxic substances of both exogenous and endogenous origin (ethanols, heavy metal salts, excess bilirubin, urea, cholesterol compounds, histamines, some allergens, waste products of pathogenic bacteria, components of other drugs, etc.). d., reducing the level of endoxification;
- lactulose, a synthetic disaccharide (fructose and galactose). Once in the cavity of the colon, lactulose undergoes a process of fermentation and breakdown, forming important organic acids that suppress the proliferation of pathogenic flora, regulating peristalsis and absorption of fluid in the lower parts of the digestive tract.
The complex effect of the two active components of Lactofiltrum reduces the concentration of toxins in the intestinal cavity and restores the natural balance of microorganisms.
Release forms of Lactofiltrum
The drug is produced under the commercial names Laktofiltrum and Laktofiltrum Eco. The composition of both drugs, the active and main accompanying components are identical, however, Lactofiltrum Eco is not presented in tablet form, but is more convenient for childhood options: lozenges, powder for dissolution in liquid, and tablets.
Depending on the manufacturing option, Laktofiltrum Eco may also contain flavoring agents. Moreover, according to the register, Lactofiltrum is classified as an officially registered medicinal product, and Eco is classified as a biologically active additive (BAA) due to the specific policies of the manufacturer.
The active components of all forms of release, regardless of the name, are the same, but their volume differs. Instructions for use make it easy to calculate the dosage required for different ages and the frequency of taking different forms of Lactofiltrum.
In what cases is Lactofiltrum prescribed?
The main indications for the use of the drug are based on the presence of toxic substances in the intestinal lumen that adversely affect the human body. Among such conditions, the following are indicated as indications:
- intestinal dysbiosis, including after diseases of a bacterial or viral nature, antibiotic therapy, poisoning, etc. in order to restore the balance of the natural intestinal flora;
- as part of complex therapy liver cirrhosis, hepatitis;
- V complex treatment irritable bowel syndrome;
- for allergic reactions, manifestations of atopic dermatitis, urticaria as part of general therapy.
Lactofiltrum: instructions for use
Regardless of the patient’s age, the drug must be taken three times a day before main meals, 30-60 minutes before meals, with a sufficient amount of water. Tablet forms can be crushed or the powder can be used to prepare solutions.
The dosage of a single dose depends on the age of the patient. The following doses are recommended for tablets:
- at the age of 1 to 3 years, ½ tablet per dose;
- from 3 to 7 years, whole tablet;
- from 8 to 12 years 2 or 3 tablets depending on the child’s body mass index;
- over 12 years old and adults 2-3 tablets as prescribed by a doctor.
Average duration of treatment for all age groups is 14-21 days. Prolonged courses of therapy are possible only as prescribed by a specialist.
Contraindications to taking Lactofiltrum and side effects
Obvious contraindications include the presence of bleeding in the digestive tract of any etiology, obstruction of any part of the intestine, galactosemia (carbohydrate metabolism disorder), individual sensitivity to the components of the drug, including allergic reactions to flavorings, etc. If an allergy or individual hypersensitivity reaction occurs, you must stop taking the drug and contact a specialist to select a different form of the drug or an analogue of the drug.
According to the instructions for the drug, caution should be exercised when prescribing Lactofiltrum in any form to patients with atonic bowel dysfunction, as well as during exacerbation peptic ulcer stomach and duodenum.
Information about the possibility of taking this drug during pregnancy and breastfeeding missing, since studies involving this group of patients have not been conducted. However, the components of the drug do not have a teratogenic effect, do not have a detrimental effect on the fetus and mother if the indicated doses are observed, and do not fall into breast milk during lactation.
Lactofiltrum: side effects when taken
Lactofiltrum is classified as a medicine with a low number of registered side effects. According to information from the manufacturer's instructions, intestinal dyspepsia is observed in statistically significant but rare quantities ( increased gas formation, manifestations of flatulence, stool liquefaction).
If the recommended doses are exceeded, hardening of the stool, difficulty in defecation (constipation), and pain in the abdominal area may be observed, which is primarily due to an excess of the sorbing component. No specific therapy is required for overdose; use of the drug should be discontinued until symptoms disappear completely and consultation with your doctor is required.
Lactofiltrum and other medications: combination of doses
Lactofiltrum does not have a direct effect on the therapeutic effect of taking other medications. However, it must be remembered that the sorbent in the drug can bind and remove not only toxic substances, but also drug components. Therefore, oral (internal) medications should be taken at intervals, and if in doubt, consult a specialist.
According to the instructions, it is optimal to take Lactofiltrum 60 minutes before meals, so you should be very careful when combining it with medications, which should also be taken before meals.
Photo of the drug
Latin name: Lactofiltrum
ATX code: A07BC
Active substance: Lactulose + Ligninhydrolysis (Lactulosum + Ligninumhydrolisatum)
Analogues: Filtrum, Polyphepan
Manufacturer: STI-MED-SORB (Russia)
Description is valid on: 04.10.17
Lactofiltrum - sorbent plant origin, which is used to normalize intestinal microflora and detoxify the body. The drug is characterized by an immunomodulatory effect.
Active substance
Lactulose + Lignin hydrolised.
Release form and composition
Available in tablet form for oral administration and gel for external use.
Indications for use
- restoration of normal intestinal microflora (including after the use of antibacterial drugs);
- complex treatment of IBS (irritable bowel syndrome);
- complex therapy of liver cirrhosis and hepatitis;
- complex treatment allergic manifestations: urticaria, atopic dermatitis;
- therapy for a number of digestive disorders caused by dysbacteriosis, in particular flatulence, bloating, constipation, diarrhea, pain in the epigastric region;
- complex therapy of chronic colitis;
- treatment of infectious diseases of the digestive tract, such as salmonellosis and dysentery;
- strengthening the immune system during annual seasonal diseases.
Indications also include various poisonings and intoxications, viral and infectious diseases. In addition, the drug is taken for acne, hair loss and other cosmetic problems.
Contraindications
- intestinal obstruction,
- galactosemia,
- gastrointestinal bleeding,
- intolerance to the drug due to hypersensitivity to its components.
Use with extreme caution in patients with diseases such as:
- intestinal atony;
- stomach and duodenal ulcers (in the acute stage).
Instructions for use Lactofiltrum (method and dosage)
The gel is taken orally, 1 hour before meals or taking medications, with a sufficient amount of water. You can pre-grind the tablet.
The application diagram according to indications is as follows:
- adults and children over 12 years old should take 2-3 tablets. three times a day;
- children 8-12 years old - 1-2 tables. three times a day;
- children 3-7 years old – 1 table. three times a day;
- children 1-3 years old – 0.5 tablet. three times a day.
The average duration of treatment is 2-3 weeks. If necessary, you can carry out repeat courses therapy.
Side effects
When used in some cases, the following may occur: side effects:
- diarrhea,
- flatulence,
- allergic reactions to individual components of the drug.
Overdose
In case of an overdose of the drug, constipation and abdominal pain are observed. In this case, the appointment must be cancelled.
Analogs
Filtrum, Polyphepan.
pharmachologic effect
Lignin being complex organic compound, which is obtained as a result of the hydrolysis of wood, has the ability to bind and retain a number of different substances on its surface, in particular:
- organic and inorganic compounds;
- exotoxins;
- endotoxins;
- pathogenic microflora;
- salts of heavy metals;
- alcohol;
- allergens;
- medicines.
Lactofiltrum is also prescribed in cases of excess metabolic products in the body, which can provoke the development of endogenous toxicosis, namely:
- serotonin;
- bilirubin;
- histamine;
- cholesterol;
- urea.
The active substance of the drug, lignin, is not toxic, so it is not absorbed into the general bloodstream and into fully is excreted from the intestines within 24 hours without disturbing the secretion and motility of the intestinal tract.
The second active component of Lactofiltrum - lactulose - is classified as synthetic prebiotics and synthetic disaccharides. It is characterized by the property of being released in the large intestine without being absorbed into it upper sections and in the stomach. Directly in the colon, this prebiotic acts as a substrate that stimulates the growth of bifidobacteria and lactobacilli. During hydrolysis in the large intestine, lactulose is capable of forming organic acids (lactic, formic and acetic), which suppress the reproduction and growth of pathogenic bacteria and inhibit the synthesis of nitrogen-containing toxins pathogenic flora. And thanks to the reduction in the amount of nitrogen-containing substances in the intestines, there is stimulation of its motility and improvement of peristalsis, as well as an increase osmotic pressure.
Thus, the utilization of pathogenic microorganisms and the formation of bifidobacteria and lactobacilli determines the effective restoration of the colon microflora, as well as the optimization of lipid, carbohydrate and protein metabolism. At the same time, the absorption of vitamins and microelements from the large intestine improves, and the severity of the endogenous toxic state of the body decreases.
Improves local immunity and also reduces the severity of allergic reactions and manifestations of intoxication.
special instructions
Can be used with other medications if taken separately.
During pregnancy and breastfeeding
There is no information on the safety of use during pregnancy and lactation.
Lactofiltrum is an enterosorbing agent designed to normalize intestinal microflora. It is also an effective immunomodulator (a group of substances that stimulate immune processes in the body).
The use of the medication helps strengthen the immune system, remove pathological toxins from the body and relieve symptoms of intoxication of various etiologies. Most often, the drug Lactofiltrum is used as a component of complex therapy for allergic manifestations and disorders of the gastrointestinal tract.
Despite enough high level safety, the medication can only be prescribed by a qualified specialist after diagnosing the patient’s body.
Clinical and pharmacological group
Enterosorbent that regulates the balance of intestinal microflora.
Conditions for dispensing from pharmacies
Dispensed without a doctor's prescription.
Prices
How much does Lactofiltrum cost? The average price in pharmacies is 300 rubles.
Release form and composition
The product is available in dark brown tablets with white-gray splashes. The shape is flat-cylindrical. What the tablets help with is indicated in the corresponding section.
1 tablet contains the following active ingredients:
- Hydrolysis lignin – 355 mg;
- Lactulose – 120 mg.
Auxiliary components: magnesium stearate – 5 mg, croscarmellose sodium – 20 mg.
Pharmacological effect
The pharmacological action of the enterosorbent is characterized by those properties that are inherent in lignin and lactulose, which are included in its composition as active components.
Hydrolytic lignin is a sorbent of natural origin, consisting of wood hydrolysis products. It is characterized by high sorption activity and a nonspecific detoxification effect. It is able to bind in the intestines and remove pathogens and their toxins from the body, and its effect also extends to medications, any allergen, ethanol, heavy metal salts and excesses of certain metabolic products: urea, cholesterol, bilirubin, serotonin, histamine, and other products metabolic processes, under the influence of which endogenous toxicosis can develop.
Lactulose is a synthetic disaccharide that is capable of stimulating the growth of lacto- and bifidobacteria in the colon under the influence of fermentation of normal intestinal microflora, acting as a substrate. As a result, organic acids are formed: lactic, acetic and formic, which are able to suppress the growth of pathogens and reduce the content of their metabolic products, which are nitrogen-containing toxic substances. Due to this, the osmotic pressure in the lumen of the colon increases and peristalsis is stimulated.
Indications for use
Adult patients and children over 1 year of age are prescribed the use of the drug Lactofiltrum for the treatment of the following pathologies:
- and (as part of a medicinal complex);
- seasonal decrease in immunity;
- (including after the use of antibiotics);
- chronic form (as part of a drug complex);
- (in combination with other medications);
- cosmetological pathologists (as one of the drugs for the treatment of acne, hair loss, etc.);
- allergic manifestations (as one of the components of complex therapy and atopic eczema);
- various disorders of normal digestion due to dysbiosis, accompanied by flatulence, bloating, painful sensations in the abdominal area and diarrhea.
Use for acne
Lactofiltrum gets rid of acne quite effectively. This process occurs thanks to a special sorbent contained in the preparation. It cleanses the patient’s body of waste, toxins, and harmful substances. In addition, the intestinal microflora is restored, as well as the automicroflora is restored.
Lactofiltrum for acne should be taken for 14 days. A few days after starting treatment, the patient should notice positive result. Acne begins to gradually disappear, inflammation becomes less noticeable, and unevenness smoothes out. Lactofiltrum has earned the most positive reviews. The use of this drug proves that a healthy intestine is the key to clean and beautiful skin. People who underwent treatment and got rid of gastrointestinal diseases noted a significant improvement in their facial condition.
In some cases, Lactofiltrum does not help with acne. This factor is explained by the fact that the patient increased sensitivity to the drug, to its individual components, or other problems have arisen. Therefore, before using the drug, you need to familiarize yourself with the contraindications.
Contraindications
Lactofiltrum is prohibited when:
- galazoctemia;
- bleeding from the gastrointestinal tract;
- intestinal obstruction;
- hypersensitivity to lactulose or lignin.
In the presence of intestinal atony, gastric and duodenal ulcers in an acute course, the drug is prescribed with caution, strictly under medical supervision.
Use during pregnancy and lactation
There are no data on the safety of using Lactofiltrum during pregnancy and breastfeeding.
During pregnancy and lactation, take only as prescribed by a doctor.
Dosage and method of administration
The instructions for use indicate: Lactofiltrum tablets are taken orally, if necessary, after preliminary crushing, with water, 1 hour before meals and taking other medications.
- Adults and children over 12 years of age are prescribed 2-3 tablets. 3 times a day, children aged 8 to 12 years – 1-2 tablets. 3 times a day, children aged 3 to 7 years – 1 tablet. 3 times/day, children aged 1 to 3 years – 1/2 tablet 3 times/day.
The average duration of treatment is 2-3 weeks. Long-term use of the drug and repeated courses of treatment should be carried out only on the recommendation of a doctor.
Side effects
Safe components in the composition of the sorbent rarely cause negative symptoms. Most reactions occur when the composition is used incorrectly, the frequency or the one-time norm for a certain age is violated.
In rare cases, there are:
- digestive disorders: bloating, diarrhea;
- skin reactions: urticaria, itching, swelling.
Overdose
special instructions
The drug can be used in complex therapy together with other drugs, subject to the rules of separate administration.
Drug interactions
Due to the fact that the lignin contained in the drug binds some substances, it can reduce the effect of certain medications, so Lactofiltrum must be used together with other medications, observing an hourly interval.
Tablets are dark brown with white-gray inclusions, flat-cylindrical in shape, with a chamfer and a score.
Compound
Hydrolyzed lignin 355 mg
Lactulose 120 mg
Excipients: croscarmellose sodium, magnesium stearate.
Pharmacodynamics
The pharmacological effect of the drug Lactofiltrum® is due to the properties of its active components - lignin and lactulose.
Hydrolytic lignin is a natural enterosorbent, consisting of hydrolysis products of wood components, has high sorbing activity and a nonspecific detoxification effect. Binds in the intestines and removes from the body pathogenic bacteria and bacterial toxins, medications, heavy metal salts, alcohol, allergens, as well as an excess of certain metabolic products, incl. bilirubin, cholesterol, histamine, serotonin, urea, other metabolites responsible for the development of endogenous toxicosis.
Lactulose is a synthetic disaccharide, the molecule of which consists of galactose and fructose residues. In the colon, lactulose as a substrate is fermented by normal intestinal microflora, stimulating the growth of bifidobacteria and lactobacilli. As a result of the hydrolysis of lactulose in the large intestine, organic acids are formed - lactic, acetic and formic, which suppress the growth of pathogenic microorganisms and, as a result, reduce the production of nitrogen-containing substances. toxic substances. The described process leads to an increase in osmotic pressure in the lumen of the large intestine and stimulation of peristalsis.
The complex effect of the drug is aimed at normalizing the microbiocenosis of the large intestine and reducing the intensity of endogenous toxic conditions.
Pharmacokinetics
Hydrolytic lignin is not absorbed and is completely eliminated from the intestine within 24 hours.
Lactulose is not absorbed or hydrolyzed in the stomach and upper intestines. Hydrolysis of lactulose occurs in the colon.
Side effects
From the digestive system: rarely - flatulence, diarrhea.
Other: allergic reactions.
Selling Features
Available without a prescription
Special conditions
The drug can be used in complex therapy together with other drugs, subject to the rules of separate administration.
Indications
Disturbances of intestinal microflora, incl. as a result of antibiotic therapy;
Irritable bowel syndrome (as part of complex therapy);
Hepatitis and cirrhosis of the liver (as part of complex therapy);
Allergic diseases (atopic dermatitis, urticaria) - as part of complex therapy.
Contraindications
Intestinal obstruction;
Gastrointestinal bleeding;
Galactosemia;
Hypersensitivity to the drug.
The drug should be used with caution during exacerbation of gastric and duodenal ulcers and intestinal atony.
Drug interactions
The therapeutic effect of some drugs taken orally may be reduced.
Lactofiltrum is a drug for the treatment of intestinal dysbiosis. The product can be purchased at a pharmacy without a prescription, and is used mainly to improve digestion, constipation, diarrhea and other bowel disorders. But sometimes it is prescribed in the complex treatment of acne.
How it works
Lactofiltrum tablets contain lactulose, a natural intestinal sorbent. When the drug enters the intestines, it adsorbs on its surface various substances, including toxic ones.
Taking Lactofiltrum allows you to eliminate from the intestines substances that negatively affect digestion, causing flatulence and diarrhea.
The drug also creates conditions for the growth and development of intestinal microflora, which also helps normalize digestion.
Due to the fact that lactulose is a disaccharide, which includes fructose and galactose, it is not only a sorbent, but also a nutrient medium for lactobacilli that live in the intestines.
The tablets themselves do not contain bacterial bodies, so their effect on dysbacteriosis takes a long time to occur. In this case, Lactofiltrum can be combined with preparations that contain bacterial mass.
Dysbacteriosis
The exact cause-and-effect relationship between intestinal dysbiosis and acne has not been established. However, there is a relationship between these two pathologies - disruption of the intestinal microflora is one of the reasons that negatively affects the condition of the skin.
Normally, the basis of the intestinal microflora is lactic acid bacteria, and to a lesser extent – bacteria of other species, including pathogenic ones, which are present in small quantities.
Lactobacilli fill ecological niche, and also participate in the digestion of food, although their importance in this regard is small.
With dysbacteriosis, the number of “useful” lactic acid bacteria decreases, and their place is taken by other organisms.
At the same time, the processes of fermentation and decay are activated in the intestines.
The resulting gas causes bloating, flatulence, and complicates peristalsis. Which in turn stimulates bacterial decomposition of food. The pathological process develops in a circle, while digestive disorders worsen. All pathological processes occurring during dysbacteriosis interfere with normal absorption nutrients
from the intestines. The body begins to experience a deficiency of important substances, and the skin also suffers from this. Functioning is impaired sebaceous glands
, in sebum the content of substances useful for the epidermis decreases, but its amount increases.
As a result, the skin becomes oilier, but at the same time more susceptible to adverse environmental factors.
If an infection gets into the blocked duct, which happens due to improper skin care and violation of personal hygiene rules, the pimple becomes inflamed and a purulent pimple is formed.
Squeezing such pimples can contribute to the spread of infection and the appearance of new pustules on the skin, which makes the course of acne persistent.
How to take Lactofiltrum (instructions for use for acne)
For acne, taking Lactofiltrum tablets helps normalize digestion. It improves absorption useful substances from food, reduces the formation and entry into the blood of harmful substances formed as a result of putrefactive and fermentation processes.
There is no need to expect a quick effect, but not only the patient’s well-being gradually improves, but also his appearance. Sebum production returns to normal, its consistency becomes less thick, and the risk of blockage is reduced.
In such circumstances, new pimples do not appear, and existing ones are easier to eliminate. The product is used in complex therapy to achieve the greatest effect.
The tablets are taken orally one hour before meals. Concomitant use with food may reduce the effectiveness of Lactofiltrum. Dosage for adults and adolescents – 2-3 tablets three times a day.
The duration of treatment is up to 3 weeks. You can take other medications in parallel with Laktofiltrum, but you must observe an hour interval between taking medications, otherwise the effectiveness of both drugs will decrease.
Children under 12 years of age require a lower dose and must take the drug after consultation with a pediatrician.
Video: Review of an effective drug
When not to
Lactulose is a disaccharide consisting of fructose and galactose molecules. Therefore, Lactofiltrum should not be taken in cases where there is intolerance to these carbohydrates - galactosemia, lactase deficiency, fructose metabolism disorders.
At the same time diabetes mellitus You can take Lactofiltrum, but be sure to monitor your glucose levels.
Intestinal bleeding, intestinal obstruction and other serious pathologies are a clear contraindication to taking the medicine.
You should also refrain from taking the medicine if there is a suspicion of any serious intestinal pathology - severe pain in the abdomen, absence of stool for more than 2 days or blood in the stool (black stool).In this case, the underlying pathology should be addressed, and taking Lactofiltrum will not have any beneficial effect.
You should refrain from taking Lactofiltrum in case of exacerbation of duodenal or gastric ulcer and intestinal atony of any origin.
In this case, there may be no harm from taking the drug, but there will be no benefit from taking it in this situation. Among the side effects that Lactofiltrum can cause are allergic reactions, constipation, and loss of appetite. Very rarely, it can cause flatulence or diarrhea - if taken with normal composition
microflora. If side effects become so pronounced that they worsen the patient’s well-being, you should immediately stop taking medicinal product
and consult a doctor. Overdose phenomena are rare.
Complex therapy for acne
The instructions for using Lactofiltrum for acne indicate that it should be taken as part of complex therapy - this way its effectiveness is higher.
A comprehensive approach includes skin care, medication and lifestyle changes. In order to achieve the desired effect, you should follow all the doctor’s recommendations - this will solve the problem. Impact on digestive system
- includes several components:
- Normalization of nutrition.
- Treatment of intestinal pathologies.
Eliminate toxins. Normalizing your diet is the first thing to do.
You should pay attention to what exactly and how much the patient consumes. It is important to review your diet in favor of easily digestible low-fat foods, vegetable oilscontaining vitamins A and E, fruits, dairy products and vegetable salads. This will increase the supply of substances necessary for the skin, as well as improve their availability. Should be limited fatty foods , as well as dishes that stimulate rotting and fermentation - White bread
, legumes, cabbage. Treatment intestinal diseases
is a gastroenterologist. Elimination of toxins produced during pathological processes in the intestines, necessary to maintain normal work
digestive tract.
Lactofiltrum and other intestinal sorbents are used precisely for this purpose. Reviews indicate their fairly high effectiveness. It is also necessary to properly care for your face - use nourishing and moisturizing creams, wash with special foams and gels (preferably those designed for problem skin
). To avoid infection, you should treat your skin with antiseptics. If the reason is serious general illness
Photo: Before and after
Lactofiltrum is a medicine that can solve a number of digestive problems. You need to take it on the recommendation of a doctor so that it is more effective and healthy.
