Lykopid is a drug of an immunomodulating nature, which is an element of bacterial cell wall, which has the main ability to influence (activate) cells immune system: B- and T-lymphocytes, macrophages.
Lykopid: properties and indications
This drug has very diverse properties that characterize its immunomodulatory nature. Properties of Lykopid:
- activates cells of the monocyte-macrophagan series;
- enhances phagocytosis;
- activates the expression of HLA-DR antigens;
- increases the activity of lysosomal enzymes, which, in turn, leads to the activation of antibodies against tumor cells;
- enhances the differentiation and proliferation of B- and T-lymphocytes;
- accelerates the synthesis of immunoglobulins, macrophages and natural killer cells;
- reduces the intensity of inflammatory processes;
- stimulates antitumor immunity...
Indications of the drug
Likopid 10 mg and 1 mg tablets are used for adults in the following cases:
- for infections of the lower and upper respiratory tract chronic nature;
- for chronic inflammatory diseases skin and soft tissues flowing into acute form(as well as for postoperative complications);
- for eye herpes;
- for tuberculosis;
- for various forms of psoriasis;
- if the cervix is affected by the papilloma virus.
Likopid tablets for children (1 mg) are used in the following cases:
- in case of purulent-inflammatory processes of a chronic nature of soft tissues and skin, occurring in an acute form;
- for infections of a chronic nature of the lower and upper respiratory tract, both in remission and in acute stage course of the disease;
- for hepatitis C and B;
- with herpes virus at any stage and localization.
Contraindications for Lykopid are caused only by individual intolerance to the drug and the period of pregnancy.
Lykopid: instructions for use
The drug for adults is recommended to be taken orally half an hour before meals (10 mg tablets) and sublingually (1 mg tablets).
- During infectious diseases of the lower and upper sections respiratory tract, the drug is used orally at a dose of 5-10 mg daily, 1 time per day. The course of treatment is 10 days.
- For postoperative complications, Likopid is used sublingually as a prophylaxis in an amount of 1-2 mg daily, once a day for 5-10 days.
- For purulent-septic lesions of soft tissues and skin moderate severity the drug is used sublingually at 2 mg two to three times a day for 10 days, and when severe forms- 10 mg once a day. The course of treatment is 10 days.
- For tuberculosis, the drug is administered orally at a dose of 10 mg once a day for 10 days.
- For eye herpes, take 10 mg orally twice a day for 3 days, after a three-day break the course must be repeated.
- For papilloma virus, Lykopid is used orally once daily for 10 days, 10 mg.
- For psoriasis, when the affected area is moderate, the dose of the drug is 10 mg. Take 1-2 times a day for 10 days and then every other day, 10-20 mg for another 10 days. When the affected area is large, take Likopid orally 2 times a day, 10 mg for 20 days.
Lykopid for children at the age of 1 to 16 years it is necessary to use 1 mg tablets.
- At infectious diseases respiratory tract and skin inflammation, the drug should be taken 1 tablet. 1 time per day for 10 days.
- For herpes Likopid, take 1 tablet 3 times a day for 10 days.
- At viral hepatitis C I B take the drug 3 times a day at a dose of 1 mg for 20 days.
- Infants for persistent infections, the drug is prescribed orally 2 times a day at a dose of 500 mcg for 7-10 days.
Side effects of the drug:
IN in some cases it is possible to increase body temperature to 38 degrees. C, which is not a reason to discontinue taking Likopid.
Likopid, which has very favorable reviews from doctors, should still be taken with caution, especially during pregnancy and lactation.
Lykopid: price and sale
This drug is quite popular and therefore it is not difficult to purchase. You can buy Lykopid at any pharmacy, or you can also order it online. There is no problem with this. The main thing here is not to “run into” counterfeit products. That is why we advise you not to buy the drug directly, even from people you know well or in dubious establishments, but only in official medical institutions or from distributors of the manufacturer. When purchasing, be sure to ask the seller for a certificate of product conformity. The price of Lykopid is the same almost everywhere, and if it differs, it is very insignificant.
Lykopid and Transfer factor
(very important note)
The cost of Lykopid is on average about 200 rubles. for 10 tablets, a course of therapy will require about 100 tablets, i.e. a course of treatment with this drug will cost somewhere 2000 rub., and the result is not guaranteed and requires repeated repetition.
Exactly the same functions are performed by Transfer factor, the package of which contains 90 capsules and its cost is about 2000 rub. Only TF has no contraindications and does not cause any side effects, overdose is impossible and has no age restrictions. Among other things, its effect on our body is deeper and more dramatic - it puts in order damaged human DNA, i.e. removes the cause of the disease, rather than treating its consequences.
But if you still decide to take Lykopid, then we advise you to take it with TF in combination, because When taken in such a complex manner, TF neutralizes all its side effects and restores the microflora of the stomach, which is disrupted by Lykopid, and this is one of the key links in our immunity.
you will read about the use of TF for various diseases.
In the composition of the product Lycopid contains active ingredient glucosaminylmuramyl dipeptide (GMDP) .
The drug also contains additional substances, including sucrose and lactose.
Release form
The product is available in the form of flat-cylindrical round tablets. Tablets with bevel, white.
Likopid 10 mg No. 10 is contained in blisters of 10 pieces; there can be one or two blisters in a cardboard package.
pharmachologic effect
Lycopid is a drug that has the properties . It contains the active component glucosaminylmuramyl dipeptide, which, when entering the body, binds to specific centers in the endoplasm of T-lymphocytes and phagocytes. As a result, under the influence of the drug, the phagocytic activity of neutrophils and macrophages is stimulated, and their cytotoxic and bactericidal activity increases.
Likopid increases the proliferation of B- and T-lymphocytes, promotes the active production of specific antibodies. Activates the production of tumor necrosis factor, interferon gamma, interleukin-6, interleukin-1, interleukin-12, and the production of colony-stimulating factors. Under the influence of GMDP, the activity of killer cells increases.
The drug can stimulate antitumor immunity in the body.
Pharmacokinetics and pharmacodynamics
After oral administration, the bioavailability of GMDP is approximately 7-13%. In the blood plasma, the highest concentration is observed within an hour and a half after taking the drug orally. It binds weakly to blood albumin.
The half-life is 4.29 hours. It is mainly excreted from the body in the urine, unchanged.
Indications for use
The drug is prescribed to patients as part of complex treatment for diseases accompanied by secondary . It is used for the following diseases and conditions in adults and children:
- inflammatory purulent diseases skin and soft tissues in acute or chronic form, including those that appear after surgical interventions;
- infectious diseases provoked by a virus (diseases of different localization);
- when chronic course viral hepatitis B and C;
- with (including atrophic form), as well as infections caused by person;
- at pulmonary tuberculosis , infectious diseases lungs;
- in case of chronic infectious diseases of the respiratory tract (upper and lower, during exacerbation or remission).
Contraindications
The use of this remedy is contraindicated in the following cases:
- during manifestations ;
- during pregnancy or breastfeeding;
- in case of exacerbation of autoimmune ;
- for illnesses accompanied by severe fever or elevated temperature body (>38 °C).
Side effects
In general, patients tolerate the drug well. Sometimes in the first days of taking the drug, people may develop hyperthermia. But it is not necessary to cancel glucosaminylmuramyl dipeptide.
Likopid tablets, instructions for use (Method and dosage)
Instructions for use of Licopid indicate that the tablets should be taken orally or sublingually.
To obtain the maximum therapeutic effect, GMDP should be taken half an hour before meals. The exact dosage of the drug and the regimen for its administration are determined by the doctor, taking into account the characteristics of the course of the disease, the use of other drugs and other individual issues.
If surgery is planned, in order to prevent the development of complications, Lykopid should be taken 1 mg per day. For prophylaxis, you need to use the drug for 10 days.
When purulent lesions Likopid should be taken 2 mg 2-3 times a day. If severe lesions are observed, the dose may be increased to 10 mg per day for 10 days.
When chronic infectious diseases lungs, the drug should be taken 1-2 mg per day. If the patient is suffering tuberculosis , the dosage is increased to 10 mg per day, taken for 10 days.
In case of illness caused by infection herpes , it is indicated to take 2 mg of Lykopid 1-2 times a day. In case of severe herpes, you need to take the drug 10 mg 1-2 times a day. Therapy lasts for 6 days. When ophthalmoherpes You need to take 10 mg tablets twice a day for three days. Next, you need to interrupt the course for 3 days, after which taking the tablets in the same dose is repeated again. In general, for the course of treatment of ophthalmoherpes, the dose of Likopid is 120 mg.
If the patient has cervical lesions , Related papillomavirus , then the drug is prescribed at a dose of 10 mg per day, taken for 10 days.
Lykopid from psoriasis Prescribe 10 mg 1-2 times a day, you need to take the tablets for 10 days. Next, you need to take a break for one day and continue taking it at the same dosage. People with severe psoriasis should receive 10 mg of Licopid 2 times a day for 20 days.
Overdose
There is no data on an overdose of the drug Likopid.
Interaction
It is not recommended to prescribe Likopid and sulfonamides or tetracyclines at the same time.
When combined with cephalosporins And fluoroquinolone Lycopid potentiates their influence. Also, the drug has a similar effect when used simultaneously with semisynthetic penicillins, as well as with drugs - polyene derivatives.
When taking Lycopid and antifungal or antiviral funds mutual strengthening of the action is observed.
The absorption of glucosaminylmuramyl dipeptide is reduced when antacids and enterosorbents are taken simultaneously.
If Likopid is taken simultaneously with glucocorticosteroids , then the severity of the action of GMDP decreases.
Terms of sale
Likopid is sold by prescription.
Storage conditions
The product should be stored at a temperature of no more than 25 degrees, protected from moisture and direct sunlight.
Best before date
Likopid can be stored for 5 years.
special instructions
The ability to drive and perform other activities that require attention and concentration is not affected by taking the pills.
When treated with Lykopid in combination, the effectiveness of antibacterial, antifungal, and antiviral treatment increases. Also, taking Likopid allows you to reduce the duration of therapy and the dosage of chemotherapy drugs.
Lykopid's analogues
Level 4 ATX code matches:Exists a large number of agents that are immunomodulators. However, there are no numerous analogues.
The only structural analogue of this remedy is the drug GMDP .
Lykopid for children
Doctors recommend taking Likopid for children from the first days of life. Reviews from doctors indicate the effectiveness and safety of the product. With a prolonged course of infectious diseases, in particular pneumonia, , sepsis, enterocolitis, complications after operations in newborns, the drug is prescribed orally twice a day, 500 mcg. Treatment lasts 7-10 days.
Children under 16 years of age should receive 1 mg. The doctor determines the number of doses per day and duration of treatment depending on the disease.
During pregnancy and lactation
During Likopid should not be taken. During appointed subject to termination natural feeding for the period of taking the drug.
Immunostimulating agent. The tablets can be taken orally or under the tongue. During treatment, there is an acceleration in the production of antibodies and other biochemicals that fight inflammation and infection. It has wide range prescriptions, and can be used in childhood. To obtain the maximum effect, it is recommended to strictly follow the dosage and dosage regimen prescribed by your doctor. The drug has low toxicity and extremely rarely causes side effects.
Dosage form
The drug is available in tablets of 1 and 10 mg, which can be taken orally or sublingually.
Description and composition
The drug is available in round, flat-cylindrical white tablets that are chamfered.
They contain glucosaminylmuramyl dipeptide as an active ingredient. In addition, they contain the following excipients:
- milk sugar;
- E572;
- potato starch;
- sucrose;
- methylcellulose.
Pharmacological group
Lykopid is an immunomodulator that contains a complete synthetic analogue of natural peptidoglycan. It is a biologically active repeating fragment of the cell wall structure of a microorganism. Once inside the body, Lykopid triggers the immune system.
The drug increases the production of specific antibodies, T and B cells, and increases the cytotoxic and antimicrobial activity of phagocytes.
The active substance binds to receptors that are localized in the endoplasm of phagocytes and T cells, due to which the immunostimulating effect of the drug is observed.
In addition, it enhances the synthesis of interleukins, interferons, colony-stimulating factors, and increases the activity of natural killer cells.
Other effects of glucosaminylmuramyl dipeptide are also known, which were discovered during clinical trials: antitumor and antimetastatic.
Research has proven that active substance has an embryotoxic effect, does not cause congenital deformities of the fetus, chromosomal and gene mutations.
The drug has low toxicity. Its semi-lethal dosage exceeds the therapeutic dose by more than 49 thousand times for 10 mg tablets and 106 thousand times for 1 mg tablets. In experiments when the drug was taken orally 100 times higher than the therapeutic dosage, no toxic effects on the central nervous system were detected. nervous system, heart, blood vessels and other vital organs.
The maximum concentration of the drug Likopid is observed 1.5 hours after administration. The drug is excreted primarily in the urine; the elimination period is 4.29 hours.
Indications for use
for adults
Likopid tablets in dosages of 1 and 10 mg are prescribed as part of complex therapy for diseases that are accompanied secondary immunodeficiency, including:
- chronic lung infections;
- acute and chronic purulent-inflammatory diseases of the skin and soft tissues, including those that developed after surgical treatment;
- herpetic infection;
- papillomas;
- chronic viral hepatitis B and C;
- psoriasis;
- pulmonary tuberculosis.
for children
For children, the drug is prescribed in a dosage of 1 mg for the following diseases:
- chronic viral hepatitis B and C;
- herpes of any localization;
- chronic infections of the upper and lower respiratory tract in the phase of exacerbation and remission;
- acute and chronic infections of the skin and soft tissues.
Likopid tablets are not prescribed to pregnant and lactating women, since there is not enough experience in using the drug in this group of patients.
Contraindications
Likopid should not be prescribed if the patient has:
- hypersensitivity to the composition of the drug;
- diseases in which there is an increase in body temperature above 38 degrees;
- Hashimoto's thyroiditis in the acute stage;
- lack of lactose, sucrose, isomaltose, impaired absorption of glucose and galactose, intolerance to fruit sugar, milk sugar, .
With caution, the drug in a dosage of 10 mg should be prescribed to older patients. age group.
Applications and dosages
for adults
The drug should be taken sublingually or orally half an hour before meals.
If you miss the next dose of the drug, if no more than 12 have passed since the moment when you needed to take the pill, you should take the drug as quickly as possible. When more than 12 hours have passed, you must take medicine continue according to the scheme, skipping the “forgotten” pill.
To prevent postoperative complications, Likopid tablets in a dosage of 1 mg should be taken once a day for 10 days.
For the treatment of purulent-septic diseases of soft tissues and skin of moderate severity, the drug is prescribed sublingually 2 mg 2 to 3 times a day. In severe cases, the drug is prescribed 10 mg once a day. Duration of therapy is 10 days.
At chronic infections respiratory tract, the drug is prescribed sublingually in a daily dosage of 1-2 mg, which must be taken at a time, the course of treatment is 10 days.
For pulmonary tuberculosis, the medicine should be prescribed orally at a dose of 10 mg once a day for 10 days.
With herpes occurring in mild form the drug is prescribed sublingually in a dosage of 2 mg, in case of severe infection - sublingual 10 mg, dosage frequency 1-2 times a day for 6 days. For eye herpes, Lykopid should be taken orally 10 mg 2 times a day for 3 days, then you need to take a 3-day break and repeat the course of therapy.
For cervical pallimatosis, the drug should be taken orally in a daily dosage of 10 mg, the course of therapy is 10 days.
For psoriasis, the drug is prescribed orally in a dosage of 10 to 20 mg, 1-2 times a day for 10 days, and then every other day in the same dose also for 10 days. In severe cases of the disease and large areas of damage, 10 mg is prescribed orally 2 times a day, the course of treatment is 10 days.
Patients in the older age group suffering from pathologies of the liver and kidneys do not require adjustment of the treatment regimen.
for children
For patients aged 1-16 years, the drug is prescribed in tablets of 1 mg at chronic diseases respiratory tract and bacterial infections skin once a day, for herpes 3 times a day. The course of treatment is 10 days.
For chronic viral hepatitis B and C, Likopid in a dosage of 1 mg should be taken 3 times a day for 20 days.
With prolonged infections (including inflammation of the lungs, bronchi, intestines, blood poisoning, postoperative complications) for newborns the drug is prescribed 500 mcg 2 times a day. The course of treatment can vary from 7 to 10 days.
for pregnant women and during lactation
The drug is not prescribed during pregnancy and lactation.
Side effects
As a rule, the drug is well tolerated, but in some patients, at the beginning of therapy, the temperature may rise to 37.9 degrees. This phenomenon is short-term and goes away on its own.
Interaction with other drugs
Glucocorticosteroids reduce the effectiveness of the drug Lykopid.
When taken simultaneously with antacids and adsorbents, the bioavailability of the drug is significantly reduced.
Likopid increases the effectiveness of semisynthetic penicillins, cephalosporin and polyene antibiotics, and fluoroquinolones. There is also an increase in the effect in relation to antiviral and antimycotic agents.
It is not advisable to prescribe it in parallel with sulfonamides and tetracyclines.
special instructions
Likopid does not affect the ability to drive a vehicle.
Therapy in elderly patients should begin with half therapeutic dose, and then if the drug is well tolerated and no adverse reactions are observed, you need to increase and take the drug as usual.
If a patient is diagnosed with psoriasis and gout at the same time, the doctor must weigh the pros and cons before starting treatment, since this may result in worsening swelling of the joints and worsening gout attacks. Therapy in such patients should be started with half the dose and only if the medication is well tolerated, it should be increased to a therapeutic dosage.
At the beginning of treatment, exacerbation of chronic and hidden pathologies is possible, which is associated with the main pharmacological effects of the drug.
Overdose
To date, there have not been any cases of overdose with Lykopid.
Storage conditions
Likopid tablets should be stored in a dry, dark place, out of reach of children, at a temperature of maximum 25 degrees. The shelf life of the medication is 5 years, after which the drug must be disposed of.
You can purchase it with a prescription. When purchasing, you need to pay attention to the following: the packaging of the medicine should have the Peptek campaign logo and the name of the medicine should be convex to the touch. This will help you avoid buying a counterfeit drug.
Analogs
Instead of Lycopid, the following drugs can be used:
- is a substitute for Likopid in the clinical and pharmacological group. The drug is available in sublingual tablets, rectal suppositories, powder from which a solution is made for injection into the muscle. The drug in injections and suppositories of 50 mg can be used to increase immunity and relieve inflammation in patients over 6 years of age. is available in tablets that can be used as an immunomodulator in children weighing at least 15 kg. It is not advisable to use it during pregnancy and lactation.
Drug price
The cost of Lykopid is on average 806 rubles. Prices range from 183 to 2366 rubles.
Immunomodulatory medications are designed to strengthen the body's defenses to prevent viral, fungal or bacterial diseases. If an infection does appear, they help to cope with it faster. One of the drugs in this group is Lykopid. Is it used in childhood and is it prescribed for prevention for children?
Composition and release form
The medication is available only in solid form, which is white, flat, round tablets. They are sold in packs of 10 pieces, packed in one blister. Lykopid does not have such forms as syrup, suspension, ointment, capsules or injections.
The active component in such tablets is a compound called “glucosaminylmuramyl peptide”. Its dosage in each tablet is 1 mg. Additionally, the preparation contains lactose monohydrate and methylcellulose, as well as calcium stearate, potato starch and sucrose.
Operating principle
The main component of Lykopid, due to which the medicine has an immunomodulatory effect, has the same structure as that of bacterial cell membranes.
Once in the human body, such a compound activates both acquired and innate immunity, resulting in increased protection against harmful microbes, fungi and viruses. It binds to proteins that are located inside macrophages, neutrophils and other phagocytes, which leads to an increase in the functional activity of such cells. This also activates the formation of B and T lymphocytes, antibodies, interleukins and other factors important for immune defense.
Indications
In childhood, Lykopid is in demand:
- as a means of treatment chronic respiratory tract infections (bronchitis, sinusitis, adenoiditis, laryngitis, etc.), as well as prophylactic, prescribed in the remission stage to prevent relapses of such diseases;
- for furunculosis, pyoderma and other purulent-inflammatory diseases m soft fabrics and skin. The medicine is also used for acute process, and for treatment chronic forms such diseases;
- At herpetic infection, for example, with a sore throat caused by the herpes virus, eye damage or a “cold” on the lips.
For adults, tablets can also be prescribed to prevent infection with ARVI as the season of respiratory diseases approaches. However, in children, according to the instructions for the tablets, such a prophylactic dose is not used.
At what age is it allowed to take it?
Children are prescribed only a drug containing the active ingredient in a dose of 1 mg. He is discharged from the age of 3 years. Tablets in which the active compound is presented in a dosage of 10 mg are not used under 18 years of age.
Contraindications
Likopid should not be given to a child:
- with hypersensitivity to any ingredient of the drug;
- with exacerbation of autoimmune thyroiditis, as well as with other autoimmune pathologies;
- with a temperature above +38 degrees;
- with metabolic disorders, in which lactose and sucrose should not be consumed.
Side effects
The manufacturer calls Likopid a non-toxic drug and assures that such a medication does not harm the central nervous system and cardiovascular system, and also does not provoke mutations or changes in internal organs.
However, some children may experience an increase in body temperature when starting to use the medicine. Often this is a short-term rise to low-grade levels, but sometimes the fever is febrile. In such a situation, the child is prescribed one of the antipyretic drugs, and there is no need to stop Likopid.
Also, in extremely rare cases, taking pills provokes diarrhea.
Instructions for use
The child is asked to keep the tablet under the tongue or swallow it half an hour before meals. Single dose for childhood is one tablet, and the method and mode of administration depends on the disease:
- For chronic infection respiratory tract, the medicine is dissolved under the tongue, one tablet per day for 10 days. To eliminate relapses, the medication is prescribed in three courses with a break of 20 days.
- For inflammatory-purulent skin pathologies or soft tissues, the medicine also needs to be taken only once a day, dissolving the tablet in oral cavity. Duration of treatment – 10 days.
- When infected with herpes, Lykopid can be either kept in the mouth or swallowed. In this case, the medicine is taken three times a day, and the course of treatment lasts 10 days.
It is best to take the medication at the same time. If for some reason the next dose was missed, but less than 12 hours have passed since the time when Lykopid should have been taken, the child is given the missed pill. Then continue to take the medication according to the prescribed regimen.
If a missed dose is detected after 12 hours or later, you do not need to take the missed drug.
In such a situation, the medicine is taken according to the original regimen without missing a dose.
Overdose
Although there have been no cases where exceeding the dose of Lykopid led to a deterioration in the child’s well-being until this time, the manufacturer suggests that after an overdose, the body temperature of a small patient may rise. In such a situation, it is recommended to give the child a sorbent and antipyretic medicine.
Interaction with other medications
- Likopid is often prescribed together with antiviral drugs, antifungals or antibiotics, as it increases the effectiveness of such drugs.
- Simultaneous use sorbents or antacids will reduce the bioavailability of the active compound Lykopid.
- Upon appointment together with glucocorticosteroid drugs, the therapeutic effect of Lykopid is weakened.
Terms of sale
Likopid is an over-the-counter medicine and therefore does not require a prescription to purchase it at a pharmacy. However, it is not advisable to buy these tablets for a child, like any other immunostimulating drugs, without consulting a doctor. The average price of one pack of tablets containing the active ingredient in a dose of 1 mg is 250-280 rubles.
Storage conditions
To medicinal properties tablets have not deteriorated, the manufacturer recommends keeping them in a place hidden from light, where it is not too humid and the temperature does not exceed +25 degrees. In addition, such a place should be inaccessible to children. The shelf life of Lykopid is 5 years. If the date marked on the package has passed, the drug must be thrown away.
Against the background of low immunity, the body is often exposed to various infectious and viral pathologies. As part of the complex treatment of such diseases and various types of secondary immunodeficiency conditions, immunomodulators are usually prescribed.
The drug of this group newest generation is Lykopid, which has a fairly wide range of applications.
Composition, release form, packaging
The active component of Lykopid is GMDP (glucosaminylmuramyl dipeptide). The auxiliary components of the drug are: sucrase and methylcellulose, potato starch, calcium stearate and lactose.
The drug is produced only in tablet form. Depending on the content of the active substance in 1 tablet, the drug is available in two dosages - 1 mg and 10 mg.
Photo (picture) of the drug Likopid 1 mg
Lykopid tablets are white in color and have a characteristic flat-cylindrical shape. Although Lykopid 1 mg and Lykopid 10 mg have one active substance, but only in different quantities, these are still slightly different drugs that differ in the rules and features of use.
For example, a drug at a dosage of 1 mg is used not only for prophylactic purposes, but also in pediatrics for the treatment of children, while tablets at a dosage of 10 mg are prescribed exclusively to adults.
The tablets are placed in blister packs of 10 pcs. in each. The pack contains 1 or 2 such cellular packages, i.e. 10 or 20 tablets.
Manufacturer
Likopid is a domestic Russian-made drug and is manufactured by Peptek CJSC.
Indications for use
Likopid is used in patients of any age, but there are some peculiarities.
Adult patients are prescribed tablets with a dosage of 10 mg and 1 mg in such cases as:
- Chronic pulmonary infection;
- Hepatitis of viral origin type C and B;
- Soft tissue and skin pathologies of a purulent-inflammatory nature, including purulent-septic processes after operations;
- Pulmonary tuberculosis;
For children, Likopid is prescribed only in a dosage of 1 mg in the presence of pathologies such as:
- Viral hepatitis type B or C;
- Purulent-inflammatory soft tissue and skin lesions of acute or chronic course;
- Herpesvirus infections with any location;
- Chronic infectious lesions of the respiratory tract in remission or acute stages.
Contraindications
Lykopid is contraindicated:
- In the presence of a feverish state or hyperthermia above 38°C, as well as in diseases accompanied by these manifestations;
- In case of individual hypersensitivity to the drug and its components;
- With aggravated thyroiditis of autoimmune origin;
- Lactating and pregnant patients.
pharmachologic effect
Likopid is an effective immunomodulator of the latest generation.
When it enters the blood, processes are launched that are identical to immunoregulation, which is normally activated after bacterial or viral agents enter the body.
GMDP binds to immune receptors, triggering a number of specific reactions, such as the active production of substances such as:
- Key cytokines;
- Gamma interferons;
- Colony-stimulating factors.
The main function and direction of action of the drug is the activation of phagocytes (innate immune cells), which are the most effective weapons against foreign bodies. In addition, Lykopid has other very valuable medicinal properties such as antimetastatic and antitumor effects. An invaluable advantage of the drug is the launch of natural immune regulation.
Glucosaminylmuramyl dipeptide is non-foreign to our body, which encounters this substance almost every day, resisting microbial attacks.
On the pharmaceutical market, the number of drugs that can boast of such naturalness is quite small.
In addition, the drug has undergone many tests, its mechanism of action has been thoroughly studied, and therefore is safe and quite predictable. Therefore, the drug is recommended to strengthen children's immunity and treatment of a fragile organism.
Tests of Lykopid showed its absolute non-toxicity, the absence of embryotoxic, teratogenic effects and chromosomal mutations. That is why Likopid is freely used in pediatrics, and a dosage of 1 mg was created specifically for the treatment of pediatric patients.
Instructions for use of Lykopid: dosage
The drug in any dosage should be taken sublingually or orally half an hour before meals on an empty stomach. The pill must be swallowed whole without damaging its integrity.
The drug must be taken every day at the same time.
If it turns out that you did not have time to take the pill on time, being less than 12 hours late, then you can take the missed dose.
If more than 12 hours have passed since the prescribed dose, then the next tablet should be taken at the appointed time, and the missed dose should not be taken. In addition, there is no need to take a double dose due to a missed dose.
1 mg
Admission rules for children and adults are slightly different.
This immunomodulator is prescribed to infants for persistent infections, including pneumonia, bronchitis, enterocolitis, postoperative sepsis and other complications in a dosage of 1/2 tablet twice a day. Duration of treatment is 1-1.5 weeks.
Older children should take Lykopid in a dosage of 1 mg:
- For herpetic infection - 1 pill three times a day, course - 10 days.
- For infectious lesions of the respiratory tract of a chronic course - a tablet sublingually once a day, course - 10 days, in total you need to take 3 courses with a 20-day break.
- For purulent-inflammatory processes on the skin and soft tissue structures - one pill sublingually once a day, course 10 days.
Adult patients should take the drug in a dosage of 1 mg as follows:
- Herpesvirus lesions of any location - 2 pills three times a day, duration of therapy - 10 days;
- Lesions of soft tissues and skin structures of a purulent-inflammatory nature - two or three times a day, 2 tablets, course - 10 days;
- Infectious lesions of the respiratory structures of a chronic course - 2 tablets daily for a 10-day course;
- For preventive purposes, Likopid 1 mg tablets are taken three times a day, one pill for a 10-day course.
10 mg
The immunomodulator Likopid in a dosage of 10 mg is prescribed only to adult patients. Moreover, older people should take half a tablet; if no adverse reactions occur, then they can switch to the full dosage.
- For STIs such as chronic trichomoniasis or HPV– 1 tablet once a day for a 10-day course.
- For psoriasis– one or two pills daily for a 10-day course, then five doses with an interval of 1 day. For severe psoriatic form (including arthritis), taking one pill twice a day is indicated, the course of therapy is 20 days.
- Pulmonary tuberculosis– daily, one tablet, course – 10 days.
- Herpes virus infection– once a day, a pill, course – 6 days. If treatment is aimed at eliminating ophthalmoherpes, then take a tablet twice a day for a 3-day course, then 3 days of rest, then repeat the course.
- Skin and soft tissue lesions of a purulent-inflammatory nature– daily, one tablet for a 10-day course.
Side effects
Doctors consider frequent adverse reactions to the use of the drug to be the occurrence of joint and muscle pain, short-term low-grade fever, etc. Most often, such reactions are observed at increased dosages of the drug 20 mg or more.
Much less often adverse reactions manifested by hyperthermia over 38°C. To eliminate febrile fever, you can take an antipyretic drug, which will not reduce the effectiveness of Lykopid. In isolated cases (less than 0.01%), patients are bothered by diarrhea.
Overdose
During drug trials, no cases of overdose were recorded. But if we theoretically proceed from pharmacological action Licopid, if the dosage is violated, low-grade hyperthermia may occur (max. 37.9 ° C).
Treatment is symptomatic and includes sorbents. No antidotes have been found.
special instructions
Drug interactions
- Likopid is able to increase the effectiveness of antimicrobial drugs, fluoroquinolones, cephalosporins and penicillins of semi-synthetic origin.
- In relation to antifungal and antiviral drugs, Lykopid exhibits synergism, that is, it acts together and mutually enhances the effect.
- When taken in combination with sorbents or antacids, the bioavailability of Lykopid is significantly reduced.
- Drugs from the glucocorticosteroid group have a reducing effect on the effectiveness of the immunomodulator.
Alcohol compatibility
The instructions do not contain data on combination with alcohol. However, the drug is not prescribed to healthy patients, and in the presence of immunodeficiency, alcohol consumption is contraindicated.
Of course, one-time consumption of a small portion of alcohol cannot harm, but if the patient drinks strong drinks throughout the entire course of treatment, then the immunomodulatory effect of the drug is completely neutralized.
